Protein Alignment CngA and cnga2b

DIOPT Version :10

• Sequence 1: NP_001188960.1
• Gene: CngA / 36806
• FlyBaseID: FBgn0261612
• Length: 840
• Species: Drosophila melanogaster
• Sequence 2: XP_073805825.1
• Gene: cnga2b / 103911065
• ZFINID: ZDB-GENE-050307-2
• Length: 682
• Species: Danio rerio
• Alignment Length: 666
• Identity: 327/666 - (49%)
• Similarity: 425/666 - (63%)
• Gaps: 54/666 - (8%)

  Fly   136 EQDEDEEEDDDDVDEDDDDEFGASVCEDNPEEAIARADHDTQQKQHYQPNASDSSYVENGRKLIQ 200
            :..|||::..:.|.....     |.|:|...|        .|:....:|..:.|.....||..:
Zfish    28 QTQEDEQDRAESVLSRSQ-----SACDDTSSE--------LQRVAALEPQDAPSRNSFRGRGAL- 78

  Fly   201 EPSKRSKPSALRRTLQ--ALRQRLTKRNRPKPPDWFLEKF---------SNTTNTDKIGKGCPAM 254
                 |:...|..||:  |.|..:.:..|   ||.|||:|         |..:|......|
Zfish    79 -----SRLVTLVVTLREWAHRSLVEEEER---PDSFLERFRGPEVRAPPSRRSNNQPDANG---- 131

  Fly   255 EDAALSSEIRGSSVLCNRLSVDPTLQSHYRWLAIVSLAVLYNIIFVVGRAVFWEINKSAPAFWYT 319
            ....::.:...:.::.   |.|.|   :|.||..::.|||||.:.:|.||.|.::....|..|..
Zfish   132 NTKGITKKQWETFIVA---SSDDT---YYYWLFFIAAAVLYNWVLLVARACFDQLQSETPIVWLV 190

  Fly   320 LDYLCDFIYLLDTLVHMHEGFLDQGLLVRDAFRLRRHYFHTKGWYLDVLSMLPTDLAYIWWPPET 384
            |||:|||:|:||:.:.:..|:|:|||||:|..:||..|.||..:.|||||:||||||||
Zfish   191 LDYICDFVYILDSCIRLRTGYLEQGLLVKDLAKLRDSYIHTFQFKLDVLSILPTDLAYI------ 249

  Fly   385 CSSLYLPCPVIVRLNRLLRINRLWEWFDRTETATGYPNAFRICKVVLAILVLIHWNACMYFAISY 449
            .:.:..|   .:|.|||||.:|::|:|:||||.|.|||.|||..:||.|||:||||||:::|||.
Zfish   250 ITGINTP---QLRFNRLLRFSRMFEFFNRTETRTNYPNIFRIWNLVLYILVIIHWNACIFYAISK 311

  Fly   450 EIGFSSDSWVY-NLNGTRNNTLQRQYIYSFYWSTLTLTTIGETPTPENDVEYLFVVADFLAGVLI 513
            .:||.||.||| |::.|....|:|.|||.|||||||||||||.|.|..|.||:|||.|||.||||
Zfish   312 SLGFGSDEWVYPNISSTEEGALRRSYIYCFYWSTLTLTTIGEMPPPVRDEEYVFVVFDFLVGVLI 376

  Fly   514 FATIVGNIGSMISNMNVARVEFQNRMDGVKQYMAFRRVGHELEARVIRWFAYTWSQSGALDEERV 578
            |||||||:||||||||..|.|||.|:|.:|.||.||:|...||.|||:||.|.|:...|:||:.|
Zfish   377 FATIVGNVGSMISNMNATRAEFQARIDAIKHYMHFRKVSRHLETRVIKWFDYLWTNQKAVDEQEV 441

  Fly   579 LAALPDKLKAEIAIQVHMDTLKQVRIFHDTEPGLLEALVLKLKLQVFSPGDYICRKGDVGKEMYI 643
            |..|||||:|||||.||:.|||:||||.|.|.|||..|||||:.||:|||||||||||:||||||
Zfish   442 LKNLPDKLRAEIAINVHLTTLKKVRIFQDCEAGLLVELVLKLRPQVYSPGDYICRKGDIGKEMYI 506

  Fly   644 VKRGKLSVVGDDGITVLATLGAGSVFGEVSVLEIAGNRTGNRRTANVRSLGYSDLFCLAKRDLWE 708
            :|.|||:||.|||:|..|.|.||..|||:|:|.|.|::.|||||||:||:||||||||:|.||.|
Zfish   507 IKEGKLAVVADDGVTQFALLTAGGCFGEISILNIQGSKMGNRRTANIRSIGYSDLFCLSKDDLME 571

  Fly   709 TLSDYPEARSTLTQRGCQLLRKDGLLDEQIFADSQRVHDSIEGGIEKLELSVENLNMRLARLLAE 773
            .:.:||:|:..|.:||.::|||.|||||.|......|.|:.| .:|:||.|::.|..|.||||.|
Zfish   572 AVIEYPDAQRVLEERGREILRKQGLLDEGIAQGGLLVMDTDE-KVERLEGSLDILQARFARLLGE 635

  Fly   774 YTASQAKIKQRLAKLE 789
            :||:|.|:|||:..||
Zfish   636 FTATQRKLKQRITALE 651

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CngA	NP_001188960.1	Ion_trans	282..529	CDD:459842	139/247 (56%)
		CAP_ED	604..717	CDD:237999	75/112 (67%)
		CLZ	720..790	CDD:465160	35/70 (50%)
cnga2b	XP_073805825.1	None