Protein Alignment CngA and cnga1a

DIOPT Version :10

• Sequence 1: NP_001188960.1
• Gene: CngA / 36806
• FlyBaseID: FBgn0261612
• Length: 840
• Species: Drosophila melanogaster
• Sequence 2: NP_001139095.1
• Gene: cnga1a / 100001558
• ZFINID: ZDB-GENE-090312-66
• Length: 697
• Species: Danio rerio
• Alignment Length: 656
• Identity: 284/656 - (43%)
• Similarity: 398/656 - (60%)
• Gaps: 52/656 - (7%)

  Fly   147 DVDEDDDDE---------FGASVCEDNPEEAIARADHDTQQKQHYQPNASDSSYVENGRKLIQEP 202
            :|:||.::.         |..:...:|.||...:.....::|:..:.........:|.:...|:.
Zfish    21 EVEEDSENPISAPTPGRVFNVNNSNNNEEEEKKKKKEKKEKKEKKEKKEKKEKKEKNQKNEKQKD 85

  Fly   203 SKRSKPSALRRTLQALRQRLTKRNRPKPPDWFLEKFSNTTNTDKIGKGCPAMEDAALSSEIRGSS 267
            :::.|.....:..:..:::..::.:.|      ||........|.|           ..|:
Zfish    86 NEKEKEKEKEKEKEKEKEKEKEKEKEK------EKEKEKEKEKKEG-----------PKEV---- 129

  Fly   268 VLCNRLSVDPTLQSHYRWLAIVSLAVLYNIIFVVGRAVFWEINKSAPAFWYTLDYLCDFIYLLDT 332
                 ..::|....:|:||.|::..|:||...::.||.|.|:.......|:.|||..|.:||.|.
Zfish   130 -----FVINPAGLLYYQWLLIITFPVMYNWTVIIARACFEELQHEYLLTWFLLDYTSDLLYLADM 189

  Fly   333 LVHMHEGFLDQGLLVRDAFRLRRHYFHTKGWYLDVLSMLPTDLAYIWWPPETCSSLYLPCPVIVR 397
            ......|:|:|||||:|...|.:.|..:..:.|||:||||||:.|.        .|.|..|.| |
Zfish   190 AFRARTGYLEQGLLVKDEKLLLKRYTDSLQFRLDVISMLPTDIFYF--------ILGLDYPEI-R 245

  Fly   398 LNRLLRINRLWEWFDRTETATGYPNAFRICKVVLAILVLIHWNACMYFAISYEIGFSSDSWVY-N 461
            :|:|||:||::|:|..:||.|.|||.||||.:|:.|:::||||||:||:.|..|||.||:||| .
Zfish   246 INKLLRLNRMFEFFKISETMTNYPNIFRICTLVMYIIIIIHWNACLYFSFSKSIGFGSDAWVYPA 310

  Fly   462 LNGTRNNTLQRQYIYSFYWSTLTLTTIGETPTPENDVEYLFVVADFLAGVLIFATIVGNIGSMIS 526
            |.......|.|:|.:|.||||||||||||||:||.|.|:.|.|.|||.||||||||||||.:|||
Zfish   311 LTEPEFGELMRKYSFSLYWSTLTLTTIGETPSPELDSEFFFHVVDFLVGVLIFATIVGNIATMIS 375

  Fly   527 NMNVARVEFQNRMDGVKQYMAFRRVGHELEARVIRWFAYTWSQSGALDEERVLAALPDKLKAEIA 591
            |||.|:.:||.|:|.:||||..|.|..|||.|||:||.|.|:...|.||..||..|||||:|||.
Zfish   376 NMNAAQAQFQARIDNIKQYMHARHVSKELEDRVIKWFDYLWTNKKAQDEREVLRYLPDKLRAEIG 440

  Fly   592 IQVHMDTLKQVRIFHDTEPGLLEALVLKLKLQVFSPGDYICRKGDVGKEMYIVKRGKLSVVGDDG 656
            :.||:||||:||||.|.|.|||..|||||:.||||||||||||||:|:||||:|.|||:||.|||
Zfish   441 MNVHLDTLKKVRIFADCEAGLLIELVLKLRPQVFSPGDYICRKGDIGREMYIIKDGKLAVVADDG 505

  Fly   657 ITVLATLGAGSVFGEVSVLEIAGNRTGNRRTANVRSLGYSDLFCLAKRDLWETLSDYPEARSTLT 721
            :|....||.||.|||:|:|.|.|::.|||||||:||:||||||||:|.||.|.|::||:|::.|.
Zfish   506 VTQFVVLGDGSYFGEISILNIKGSKAGNRRTANIRSIGYSDLFCLSKDDLMEALTEYPDAKAMLE 570

  Fly   722 QRGCQLLRKDGLLD---EQIFADSQRVHDSIEGGIEKLELSVENLNMRLARLLAEYTASQAKIKQ 783
            ::|.|:|.|||||:   .::..|.:.:.|.:......|:|....:|    :|||:...::..|::
Zfish   571 EKGRQILLKDGLLELDPSKLKPDERDLEDRVNRMYSTLQLMQTKVN----KLLAQQEETRKSIRR 631

  Fly   784 RLAKLE 789
            |:.::|
Zfish   632 RIIEIE 637

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CngA	NP_001188960.1	Ion_trans	282..529	CDD:459842	125/247 (51%)
		CAP_ED	604..717	CDD:237999	76/112 (68%)
		CLZ	720..790	CDD:465160	20/73 (27%)
cnga1a	NP_001139095.1	Ion_trans	139..381	CDD:459842	127/250 (51%)
		CAP_ED	453..569	CDD:237999	77/115 (67%)
		CLZ	569..627	CDD:465160	17/61 (28%)