DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7786 and TEF

DIOPT Version :9

Sequence 1:	NP_611101.1	Gene:	CG7786 / 36802	FlyBaseID:	FBgn0034096	Length:	192	Species:	Drosophila melanogaster
Sequence 2:	NP_003207.1	Gene:	TEF / 7008	HGNCID:	11722	Length:	303	Species:	Homo sapiens

Alignment Length:	206	Identity:	65/206 - (31%)
Similarity:	91/206 - (44%)	Gaps:	43/206 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 PILDVT---ETVSMHSE---LDAELESKNNPSYSISIPQNLRLTGLGFPGMIGAKRSSETLPAFE 66
            ||.|.|   :..|.|.|   ||..|.....|:....:..||.|......|...|..|:.:.|:..
Human    81 PIWDKTIPYDGESFHLEYMDLDEFLLENGIPASPTHLAHNLLLPVAELEGKESASSSTASPPSSS 145

  Fly    67 -YIAPPSHALQALEFPL-------------------------MELNRVGVIGGGMFPGFVHRRVR 105
             .|..||..:.:.|..|                         .:|....|.||.:|....|:...
Human   146 TAIFQPSETVSSTESSLEKERETPSPIDPNCVEVDVNFNPDPADLVLSSVPGGELFNPRKHKFAE 210

  Fly   106 GEKRP-----------IPEAQKDAKYFERRKRNNEAAKRSRDARKIREDRIAFRAALLEQENSIL 159
            .:.:|           :|:.|||.||:.|||:||.|||||||||:::|::|..|||.||:||:.|
Human   211 EDLKPQPMIKKAKKVFVPDEQKDEKYWTRRKKNNVAAKRSRDARRLKENQITIRAAFLEKENTAL 275

  Fly   160 RAQVLALRDEL 170
            |.:|..||.|:
Human   276 RTEVAELRKEV 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7786	NP_611101.1	bZIP_HLF	116..175	CDD:269843	33/55 (60%)
CG7786	NP_611101.1	coiled coil	117..175	CDD:269843	32/54 (59%)
TEF	NP_003207.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..63
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	132..176		8/43 (19%)
		bZIP_HLF	232..290	CDD:269843	33/55 (60%)
		Basic motif. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00978	235..255		15/19 (79%)
		coiled coil	236..287	CDD:269843	30/51 (59%)
		Leucine-zipper. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00978	256..263		2/6 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151883
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000980
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	6	5.700