DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7786 and Tef

DIOPT Version :9

Sequence 1:	NP_611101.1	Gene:	CG7786 / 36802	FlyBaseID:	FBgn0034096	Length:	192	Species:	Drosophila melanogaster
Sequence 2:	NP_062067.2	Gene:	Tef / 29362	RGDID:	3841	Length:	301	Species:	Rattus norvegicus

Alignment Length:	206	Identity:	66/206 - (32%)
Similarity:	92/206 - (44%)	Gaps:	43/206 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 PILDVT---ETVSMHSE---LDAELESKNNPSYSISIPQNLRLTGLGFPGMIGAKRSSETLPAFE 66
            ||.|.|   :..|.|.|   ||..|.....|:....:.|||.|......|...|..|:.:.|:..
  Rat    79 PIWDKTIPYDGESFHLEYMDLDEFLLENGIPASPTHLAQNLLLPVAELEGKESASSSTASPPSSS 143

  Fly    67 -YIAPPSHALQALEFPL-------------------------MELNRVGVIGGGMFPGFVHRRVR 105
             .|..||..:.:.|..|                         .:|....|.||.:|....|:...
  Rat   144 TAIFQPSETVSSTESSLEKERETPSPIDPNCVEVDVNFNPDPADLVLSSVPGGELFNPRKHKFAE 208

  Fly   106 GEKRP-----------IPEAQKDAKYFERRKRNNEAAKRSRDARKIREDRIAFRAALLEQENSIL 159
            .:.:|           :|:.|||.||:.|||:||.|||||||||:::|::|..|||.||:||:.|
  Rat   209 EDLKPQPMIKKAKKVFVPDEQKDEKYWTRRKKNNVAAKRSRDARRLKENQITIRAAFLEKENTAL 273

  Fly   160 RAQVLALRDEL 170
            |.:|..||.|:
  Rat   274 RTEVAELRKEV 284

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7786	NP_611101.1	bZIP_HLF	116..175	CDD:269843	33/55 (60%)
CG7786	NP_611101.1	coiled coil	117..175	CDD:269843	32/54 (59%)
Tef	NP_062067.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..70
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	130..174		8/43 (19%)
		bZIP_HLF	230..288	CDD:269843	33/55 (60%)
		Basic motif. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00978	233..253		15/19 (79%)
		Leucine-zipper. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00978	254..261		2/6 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166345402
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000980
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	6	5.700