Protein Alignment Tsf3 and Inhca

DIOPT Version :10

• Sequence 1: NP_523759.1
• Gene: Tsf3 / 36800
• FlyBaseID: FBgn0034094
• Length: 714
• Species: Drosophila melanogaster
• Sequence 2: NP_082194.1
• Gene: Inhca / 71775
• MGIID: 1919025
• Length: 700
• Species: Mus musculus
• Alignment Length: 780
• Identity: 176/780 - (22%)
• Similarity: 281/780 - (36%)
• Gaps: 198/780 - (25%)

  Fly    17 SISMCVAVQPPDDGKLRVCVVESR-----GVYRKTPKFCPLLEAKS-NIECVIGVDRLDCVRRIH 75
            ::.:|:|:   .:..:|.|||...     ..:|...|  .:|.|.. .:.||..:...:|:|.|
Mouse    13 TLGLCLAL---PEKTIRWCVVSDHEATKCSSFRDNMK--KVLPAGGPAVTCVRKMSHPECIRDI- 71

  Fly    76 KGTAHFGVLTSEDLVAARWASVEILVASELRSH----------------ESHFEYEIVAVVDNHA 124
                      |.:.|.|......::..::|..|                ::|  |.:||:.....
Mouse    72 ----------SANKVDAVTVDGALVAEADLPHHSLKPIMAEYYGSKDDPKTH--YYVVAMAKKGT 124

  Fly   125 NIHTVHDLRGARLCHPGYGLGNHWTEVLANYFEAAMVSKTCDPEMTVTEDRIASTAKYFGPSCKA 189
            ... ::.|||.:.||.|.|....|...|:....:.              .|..:.|.:|..||
Mouse   125 GFQ-LNQLRGKKSCHTGLGWSAGWYVPLSTLLPSG--------------SRETAAATFFSSSC-- 172

  Fly   190 GPWVP--DPKQDRILKNRYPSLCEMC----YEPDSCDQTDKHWGRRGALYCLTSGGGNVAWARLD 248
               ||  |.|.       :||||::|    .:..:|...:.::|..|||.||..|..:|::.:..
Mouse   173 ---VPCADGKM-------FPSLCQLCAGKGTDKCACSSREPYFGSWGALKCLQDGTADVSFVKHL 227

  Fly   249 DVRSHFGFSGIPAQSNPSDFSYLCPDGHLQPLNASQPCVWVAKPWPVVAARRSHAAQ--VQRLVT 311
            .|     |..:|.:::...:..||.|...:|:...:.|.....|..||.||.....:  :|.|:.
Mouse   228 TV-----FEAMPTKADRDQYELLCMDNTRRPVEEYEQCYLARVPSHVVVARSVDGKEDSIQELLR 287

  Fly   312 -----------------GLNHDEPDSWQNALLSLLETYHVFTVPLDNVIAIDDYLDQATAFQSAY 359
                             |..|.|...:.:|...||.      ||  ..|.|..||  ...|.||:
Mouse   288 VAQEHFGKDKSSPFQLFGSPHGEDLLFTDAAHGLLR------VP--RKIDISLYL--GYEFLSAF 342

  Fly   360 SFPECNPPRS------IVFCTTSIIQHIKC-SWLQEASQVYGVQPNIQCVRTMDEQQCLDNTKFK 417
            .    |..|.      :.:|.....:..|| .|    |.|.|  ..:.|......:.|:..|...
Mouse   343 R----NLKRGLEDSQRVKWCAVGQQERTKCDQW----SAVSG--GALACATEETPEDCIAATMKG 397

  Fly   418 ETDVVLVDQEMRVKAQRDYNLVPLLYEFAADMH--------------DRYVTIALVHKDAKFESF 468
            |.|.:.:|......|.. ..|||:|.|.....|              :.|..:|:|.|.....::
Mouse   398 EADAMSLDGGFAYVAGH-CGLVPVLAENYLSTHSSGRLGSKCVNAPLEGYYVVAVVKKSDVGITW 461

  Fly   469 RDLKGARACLPSFEGAAHLSVQET---------IVNATGKVQSLHSYFHR--------DSCLWNL 516
            :.|:|.::|        |.:|..:         |.|.||..: ..::|.|        ||.|..|
Mouse   462 KSLQGKKSC--------HTAVGTSEGWNVPMGLIYNQTGSCK-FDAFFSRSCAPGSDPDSPLCAL 517

  Fly   517 QSGRKCPLH---------YQGDEGALRCLSEGADVAFLSSDVYKKYVVGNLTSNWLTPGNHKDFR 572
            ..|...|.|         |.|..||||||.|..||||:......:...|.....|.....|:||.
Mouse   518 CVGGNNPAHMCAANNAEGYHGSSGALRCLVEKGDVAFMKHPTVLQNTDGKNPEPWAKGLKHEDFE 582

  Fly   573 VLCPYGGIEKRSNFEYCYLHWTTRGHLMTHNSSLTRRNE---IYNSLRDMDQLFGRKYKSETRPF 634
            :||..|..:..:..:.|:|      ..:.:.:..:|:::   :...|.:..:||||    ....:
Mouse   583 LLCLDGTRKPVTEAQSCHL------ARVPNRAVFSRKDKADFVRRILFNQQELFGR----NGFEY 637

  Fly   635 TLYGIFD-KRNNVLFRDDTDGLLGLQELHRDNAKRVMEHIYDRYANTQYYRNFDESGAMKSSHNL 698
            .::.:|: ...::||.|||:.|..||.          :..|..|...||....|......||..|
Mouse   638 MMFQMFESSAKDLLFSDDTECLSNLQN----------KTTYKTYLGPQYLTLMDNFRQCLSSELL 692

  Fly   699  698
            Mouse   693  692

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsf3	NP_523759.1	PBP2_transferrin	33..368	CDD:270247	85/381 (22%)
		PBP2_transferrin	369..681	CDD:270247	82/362 (23%)
Inhca	NP_082194.1	PBP2_transferrin_N	24..346	CDD:270336	85/382 (22%)
		PBP2_transferrin_C	352..684	CDD:270335	85/367 (23%)