DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tsf3 and otomp

DIOPT Version :9

Sequence 1:	NP_523759.1	Gene:	Tsf3 / 36800	FlyBaseID:	FBgn0034094	Length:	714	Species:	Drosophila melanogaster
Sequence 2:	NP_001038552.1	Gene:	otomp / 565818	ZFINID:	ZDB-GENE-040709-1	Length:	371	Species:	Danio rerio

Alignment Length:	314	Identity:	70/314 - (22%)
Similarity:	123/314 - (39%)	Gaps:	53/314 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 KSNIECVIGVDRLDCVRRIHKGTAHFGVLTSEDLVAARWA-SVEILVASELRSHESHFEYEIVAV 119
            :..:.||.|....||:::|..|||....:.::::..|.:. .:::.|.......:. ..|.:||:
Zfish    53 RGQLVCVRGQSPTDCMKQIKNGTADASTMYADEIYTAGFCYGLDVAVGESYNGVDG-INYYVVAL 116

  Fly   120 VDNHANIHTVHDLRGARLCHPGYGLGNHWTEVLANYFEAAMVSKTCDPEMTVTEDRIASTAKYFG 184
            ....::..::.::.....||||......||..:......:.:|  .|.:.....    :...:||
Zfish   117 ARTSSSDLSLLEMHERSSCHPGMRTTVGWTVPIGFLVNTSQIS--VDVQCNFPH----AVGDFFG 175

  Fly   185 PSCKAGPWVPDPKQDRILKNRYP-SLCEMCYEPDS----C--DQTDKHWGRRGALYCLTSGGGNV 242
            .||.  |.|.||:.|.  |...| :|||.|...::    |  :..::|:|..|||.|:....|:|
Zfish   176 YSCV--PGVKDPEHDP--KGNNPRNLCEACIGDENDRHICANNPRERHFGEAGALRCVAENLGDV 236

  Fly   243 AWARLDDVRSHFGFSGIPAQSNPS--------DFSYLCPDGHLQPLNASQPCVWVAKPWPVVAAR 299
            |:.:...|     |..:..::..|        |...|||||....|...:.|.....|...|..|
Zfish   237 AFVKHTTV-----FDNMQGKNQESWALDLELEDLKLLCPDGSEANLFQHESCHLAVVPTNAVVVR 296

  Fly   300 RSHAAQVQR-----------------LVTGLNHDEPD----SWQNALLSLLETY 332
            .....:|.:                 |.:.:|:.:||    .....||.::.||
Zfish   297 LEDKCRVYKFLERVQNAFGNTTEGFSLFSSVNYGQPDVLFSDSTKKLLRVMGTY 350

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tsf3	NP_523759.1	PBP2_transferrin	33..368	CDD:270247	70/314 (22%)
		PBP2_transferrin	369..681	CDD:270247
		TR_FER	370..656	CDD:214514
otomp	NP_001038552.1	TR_FER	27..363	CDD:214514	70/314 (22%)
otomp	NP_001038552.1	PBP2_transferrin	27..363	CDD:270247	70/314 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28KI0
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D125278at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11485
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11944
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	6	5.880