Protein Alignment Tsf3 and Meltf

DIOPT Version :10

• Sequence 1: NP_523759.1
• Gene: Tsf3 / 36800
• FlyBaseID: FBgn0034094
• Length: 714
• Species: Drosophila melanogaster
• Sequence 2: XP_006522295.1
• Gene: Meltf / 30060
• MGIID: 1353421
• Length: 758
• Species: Mus musculus
• Alignment Length: 752
• Identity: 164/752 - (21%)
• Similarity: 273/752 - (36%)
• Gaps: 184/752 - (24%)

  Fly    34 VCVVESRGVYRKTPKFCPLLEA-----------------KSNIECVIGVDRLDCVRRIHKGTAHF 81
            |||:|        .::|.:.:|                 :.::.||.|.....||:.|.:..|..
Mouse    18 VCVME--------VQWCTISDAEQQKCKDMSEAFQGAGIRPSLLCVQGNSADHCVQLIKEQKADA 74

  Fly    82 GVLTSEDLVAARWASVEILVASELRSHESHFEYEIVAVVDNHANIHTVHDLRGARLCHPGYGLGN 146
            ..|....:..|........|..|:...:....|..||||..::|: |::.|:|.:.||.|.....
Mouse    75 ITLDGGAIYEAGKEHGLKPVVGEVYDQDIGTSYYAVAVVRRNSNV-TINTLKGVKSCHTGINRTV 138

  Fly   147 HWTEVLANYFEAAMVS--------------KTCDPEMTVTEDRIASTAKYFGPSCKAGPWVPDPK 197
            .|...:....|:..:|              :.|.|..:... |..:...|||.||..|.......
Mouse   139 GWNVPVGYLVESGHLSVMGCDVLKALCSVPQPCAPSHSPVL-RPTAVGDYFGGSCVPGTGETSHS 202

  Fly   198 QDRILKNRYPSLCEMCYEPDS----CDQT--DKHWGRRGALYCLTSGGGNVAWARLDDVRSHFGF 256
            :         |||.:|....|    ||::  ::::...||..||..|.|:||:.:...|..:...
Mouse   203 E---------SLCRLCRGDSSGHNVCDKSPLERYYDYSGAFRCLAEGAGDVAFVKHSTVLENTDG 258

  Fly   257 SGIPAQSN---PSDFSYLCPDGHLQPLNASQPCVWVAKPWPVVAARRSHAAQVQRLVTG------ 312
            :.:|:...   ..||..||.||....:...:.|.....|        :||..|:..:.|
Mouse   259 NTLPSWGKSLMSEDFQLLCRDGSRADITEWRRCHLAKVP--------AHAVVVRGDMDGGLIFQL 315

  Fly   313 -------LNHDEPD---------SWQNALL--SLLETYHVFTVPLDNVIAIDDY---LDQATAFQ 356
                   .:|::..         |.:|.|.  |.||     .||    ||..:|   |.|  .:.
Mouse   316 LNEGQLLFSHEDSSFQMFSSKAYSQKNLLFKDSTLE-----LVP----IATQNYEAWLGQ--EYL 369

  Fly   357 SAYSFPECNP---PRSIVFCTTSIIQHIKCSWLQEASQVYGVQPNIQCVRTMDEQQCLDNTKFKE 418
            .|.....|:|   |..:.:|..|..:..||..:..|.....::|.||||.....:.|::..:...
Mouse   370 QAMKGLLCDPNRLPHYLRWCVLSAPEIQKCGDMAVAFSRQNLKPEIQCVSAESPEHCMEQIQAGH 434

  Fly   419 TDVVLVDQEMRVKAQRDYNLVPLLYEFAA--DMHDRYVTIALVHKDAKFE-SFRDLKGARACLPS 480
            ||.|.:..|...:|.:.|.|||...|..|  |..:.|..:|:..:|:.:. :..:|:|.|:|.|.
Mouse   435 TDAVTLRGEDIYRAGKVYGLVPAAGELYAEEDRSNSYFVVAVARRDSSYSFTLDELRGKRSCHPY 499

  Fly   481 FEGAAHLSVQETIVNATGKVQ--------SLHSYFHRDS----------------CLWNLQSGRK 521
            ....|...|....:...|.::        ::..:|:...                |:.:.:...|
Mouse   500 LGSPAGWEVPIGSLIQRGFIRPKDCDVLTAVSQFFNASCVPVNNPKNYPSALCALCVGDEKGRNK 564

  Fly   522 C----PLHYQGDEGALRCLSEGA-DVAFLSSDVYKKYVVGNLTSNWLTPGNHKDFRVLCPYGGIE 581
            |    ...|.|..||.|||.|.| ||||:......:...|:....|.:....:|:.:|||.|...
Mouse   565 CVGSSQERYYGYSGAFRCLVEHAGDVAFVKHTTVFENTNGHNPEPWASHLRWQDYELLCPNGARA 629

  Fly   582 KRSNFEYCYLHWTTRGHLMTHNSSLTRRNEIYNSLRDMDQLFGRKYKSETRPFTLYGIFDKRNNV 646
            :...|:.|.|     ..:.:|...:                     :.:|..||:||:.||..:
Mouse   630 EVDQFQACNL-----AQMPSHAVMV---------------------RPDTNIFTVYGLLDKAQD- 667

  Fly   647 LFRDDTDGLLGLQELHRDNAKRVMEHIYDRYANTQYY 683
            ||.||          |..|.       :..:.:::|:
Mouse   668 LFGDD----------HNKNG-------FQMFDSSKYH 687

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsf3	NP_523759.1	PBP2_transferrin	33..368	CDD:270247	87/403 (22%)
		PBP2_transferrin	369..681	CDD:270247	75/343 (22%)
Meltf	XP_006522295.1	Transferrin	23..377	CDD:395328	81/383 (21%)
		TR_FER	387..724	CDD:214514	76/345 (22%)