Protein Alignment Tsf3 and Meltf

DIOPT Version :10

• Sequence 1: NP_523759.1
• Gene: Tsf3 / 36800
• FlyBaseID: FBgn0034094
• Length: 714
• Species: Drosophila melanogaster
• Sequence 2: NP_001099342.1
• Gene: Meltf / 288038
• RGDID: 1308155
• Length: 738
• Species: Rattus norvegicus
• Alignment Length: 758
• Identity: 162/758 - (21%)
• Similarity: 266/758 - (35%)
• Gaps: 188/758 - (24%)

  Fly     1 MQWLTLILVGLFASFLSISMCVAVQPPDDGKLRVCVVESRGVYRKTPKFCPLLEAKSNIECV--I 63
            |||.|                  :..|:..|.:......:|...:....|  ::..|...||  |
  Rat    23 MQWCT------------------ISDPEQQKCKDMSKAFQGAGIQPSLLC--VQGTSTDHCVQLI 67

  Fly    64 GVDRLDCVR----RIHKGTAHFGVLTSEDLVAARWASVEILVASELRSHESHFEYEIVAVVDNHA 124
            ...:.|.:.    .|::....:|:..               |..|:...:....|..||||..::
  Rat    68 KDQKADAITLDGGAIYQAGKEYGLKP---------------VVGEVYDQDIGTSYYAVAVVRRNS 117

  Fly   125 NIHTVHDLRGARLCHPGYGLGNHWTEVLANYFEAAMVS-KTCDPEMTVTEDRIASTAKYFGPSCK 188
            |: |::.|:|.:.||.|......|...:....|...:| ..||.        :.:...|||.||.
  Rat   118 NV-TINTLKGVKSCHTGINRTVGWNVPVGYLVETGHLSVMGCDV--------LKAVGDYFGGSCV 173

  Fly   189 AGPWVPDPKQDRILKNRYPSLCEMCYEPDS----CDQT--DKHWGRRGALYCLTSGGGNVAWARL 247
            .|.......:         |||.:|....|    ||::  ::::...||..||..|.|:||:.:.
  Rat   174 PGAGETSHSE---------SLCRLCRGDSSGHNVCDKSPLERYYDYSGAFRCLAEGAGDVAFVKH 229

  Fly   248 DDVRSHFGFSGIPAQSN---PSDFSYLCPDGHLQPLNASQPCVWVAKPWPVVAARRSHAAQVQRL 309
            ..|..:.....:|:...   ..||..||.||....:...:.|.....|        :||..|:..
  Rat   230 STVLENTDGKTLPSWGKALMSQDFQLLCRDGSRADITEWRRCHLAKVP--------AHAVVVRDD 286

  Fly   310 VTG------LNH------DEPDSWQ----------NALL--SLLETYHVFTVPLDNVIAIDDYLD 350
            :.|      ||.      .|..|:|          |.|.  |.||...:.|...::.:. .:||.
  Rat   287 MDGGLIFRLLNEGQLLFSHEDSSFQMFSSKAYGQKNLLFKDSTLELVPIATQNYESWLG-QEYLH 350

  Fly   351 QATAFQSAYSFPECNP---PRSIVFCTTSIIQHIKCSWLQEASQVYGVQPNIQCVRTMDEQQCLD 412
            ......       |:|   |..:.:|..|:.:..||..:..|.....::|.||||.....:.|:.
  Rat   351 AMKGLL-------CDPNRLPHYLRWCVLSVPEIQKCGDMAVAFSRQSLKPEIQCVSAESPEHCMQ 408

  Fly   413 NTKFKETDVVLVDQEMRVKAQRDYNLVPLLYEFAA--DMHDRYVTIALVHKDAKFE-SFRDLKGA 474
            ..:....|.|.:..|...:|.:.|.|||...|..|  |..:.|..:|:|.:|:.:. :..:|:..
  Rat   409 QIQAGHIDAVTLRGEDIYRAGKAYGLVPAAGELYAEEDRSNSYFVVAVVRRDSSYSFTLDELRSK 473

  Fly   475 RACLPSFEGAAHLSVQETIVNATGKVQ--------SLHSYFHRDS----------------CLWN 515
            |:|.|.....|...|....:...|.::        ::..:|:...                |:.:
  Rat   474 RSCHPGLGSPAGWEVPIGSLIQRGFIRPKDCDVLTAVSEFFNASCVPVNNPKNYPSSLCALCVGD 538

  Fly   516 LQSGRKC----PLHYQGDEGALRCLSEGA-DVAFLSSDVYKKYVVGNLTSNWLTPGNHKDFRVLC 575
            .:...||    ...|.|..||.|||.|.| |||||......:...|:....|.:....:|:.:||
  Rat   539 EKGRNKCVGSSQERYYGYSGAFRCLVENAGDVAFLKHTTVFENTNGHNPEPWASHLRWQDYELLC 603

  Fly   576 PYGGIEKRSNFEYCYLHWTTRGHLMTHNSSLTRRNEIYNSLRDMDQLFGRKYKSETRPFTLYGIF 640
            |.|...:...|:.|.|.......:|.|                          .:|..||:||:.
  Rat   604 PNGARAEVDQFQACNLAQMPSHAVMVH--------------------------PDTNIFTVYGLL 642

  Fly   641 DKRNNVLFRDDTDGLLGLQELHRDNAKRVMEHIYDRYANTQYY 683
            ||..: ||.||          |..|.       :..:.:::|:
  Rat   643 DKAQD-LFGDD----------HNKNG-------FQMFDSSKYH 667

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsf3	NP_523759.1	PBP2_transferrin	33..368	CDD:270247	78/377 (21%)
		PBP2_transferrin	369..681	CDD:270247	76/343 (22%)
Meltf	NP_001099342.1	Transferrin	24..357	CDD:395328	81/401 (20%)
		TR_FER	367..704	CDD:214514	77/345 (22%)