Protein Alignment Tsf3 and Tf

DIOPT Version :10

• Sequence 1: NP_523759.1
• Gene: Tsf3 / 36800
• FlyBaseID: FBgn0034094
• Length: 714
• Species: Drosophila melanogaster
• Sequence 2: NP_001013128.1
• Gene: Tf / 24825
• RGDID: 3845
• Length: 698
• Species: Rattus norvegicus
• Alignment Length: 788
• Identity: 174/788 - (22%)
• Similarity: 280/788 - (35%)
• Gaps: 232/788 - (29%)

  Fly     9 VGLFASFLSISMCVAVQPPDDGKLRVCVVESRGVYRKTPKFCPLLEAKSNIECVIGVDRL----- 68
            ||...:..::.:|:||  ||                ||.|:|.:.| ..|.:|:...|.:
  Rat     5 VGALLACAALGLCLAV--PD----------------KTVKWCAVSE-HENTKCISFRDHMKTVLP 50

  Fly    69 ---------------DCVRRIHKGTA----------HFGVLTSEDL--VAARWASVEILVASELR 106
                           ||::.|..|.|          :...||..:|  |||.:       ...|.
  Rat    51 ADGPRLACVKKTSYQDCIKAISGGEADAITLDGGWVYDAGLTPNNLKPVAAEF-------YGSLE 108

  Fly   107 SHESHFEYEIVAVVDNHANIHTVHDLRGARLCHPGYGLGNHWTEVLANYFEAAMVSKTCD-PEMT 170
            ..::|  |..||||....:.. ::.|:|.:.||.|.|....|...:...|        |: ||..
  Rat   109 HPQTH--YLAVAVVKKGTDFQ-LNQLQGKKSCHTGLGRSAGWIIPIGLLF--------CNLPEPR 162

  Fly   171 VTEDRIASTAKYFGPSCKAGPWVP--DPKQDRILKNRYPSLCEMCYEPD-SCDQTDKHWGRRGAL 232
            ...::  :.|.:|..||     ||  ||.       .:|.||::|  |. .|..|...:|..||.
  Rat   163 KPLEK--AVASFFSGSC-----VPCADPV-------AFPQLCQLC--PGCGCSPTQPFFGYVGAF 211

  Fly   233 YCLTSGGGNVAWARLDDVRSHFGFSGIPAQSNPSDFSYLCPDGHLQPLNASQPCVWVAKPWPVVA 297
            .||..|||:||:.:...:     |..:|.:::...:..||.|...:|::..:.|.....|...|.
  Rat   212 KCLRDGGGDVAFVKHTTI-----FEVLPQKADRDQYELLCLDNTRKPVDQYEDCYLARIPSHAVV 271

  Fly   298 ARRSHAAQVQRLVTGLNHDEPDSWQNALLSLLET------------YHVFTVPLDNVIAIDDYLD 350
            ||..                 |..::.:..:|:.            :.:|..||...:...|
  Rat   272 ARNG-----------------DGKEDLIWEILKVAQEHFGKGKSKDFQLFGSPLGKDLLFKD--- 316

  Fly   351 QATAFQSAYSFPECNPPR-------------------------------SIVFCTTSIIQHIKC- 383
                  ||:..... |||                               .:.:|..|..:..||
  Rat   317 ------SAFGLLRV-PPRMDYRLYLGHSYVTAIRNQREGVCPEGSIDSAPVKWCALSHQERAKCD 374

  Fly   384 SWLQEASQVYGVQPN--IQCVRTMDEQQCLDNTKFKETDVVLVDQEMRVKAQRDYNLVPLL---Y 443
            .|        .|..|  |:|......:.|:|.....|.|.:.:|......|.: ..|||::   |
  Rat   375 EW--------SVSSNGQIECESAESTEDCIDKIVNGEADAMSLDGGHAYIAGQ-CGLVPVMAENY 430

  Fly   444 EFA------ADMHDR-YVTIALVHKDAKFESFRDLKGARACLPSFEGAAHLSVQETI-------- 493
            :.:      :|:..: |..:|:|.......::.:|||.::|        |..|..|.
  Rat   431 DISSCTNPQSDVFPKGYYAVAVVKASDSSINWNNLKGKKSC--------HTGVDRTAGWNIPMGL 487

  Fly   494 ----VNATGKVQSLHSY-----FHRDSCLWNLQSG-RKCPLH----YQGDEGALRCLSEGADVAF 544
                :|.. |.....|.     :.::|.|.:|..| .||..:    |.|..||.:||.|..||||
  Rat   488 LFSRINHC-KFDEFFSQGCAPGYKKNSTLCDLCIGPAKCAPNNREGYNGYTGAFQCLVEKGDVAF 551

  Fly   545 LSSDVYKKYVVGNLTSNWLTPGNHKDFRVLCPYGGIEKRSNFEYCYLHWTTRGHLMTHNSSLTRR 609
            :......:...|..|:.|......:||::|||.|..:..:.|..|:|.......:::......|.
  Rat   552 VKHQTVLENTNGKNTAAWAKDLKQEDFQLLCPDGTKKPVTEFATCHLAQAPNHVVVSRKEKAARV 616

  Fly   610 NEIYNSLRDMDQLFGRKYKSETRPFTLYGIFDKRNNVLFRDDTDGLLGLQELHRDNAKRVMEHIY 674
            :.:..:.:|   ||.:..|..|..|.|:....|  ::||||||..|..|.|          ...|
  Rat   617 STVLTAQKD---LFWKGDKDCTGNFCLFRSSTK--DLLFRDDTKCLTKLPE----------GTTY 666

  Fly   675 DRYANTQY 682
            :.|...:|
  Rat   667 EEYLGAEY 674

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsf3	NP_523759.1	PBP2_transferrin	33..368	CDD:270247	82/382 (21%)
		PBP2_transferrin	369..681	CDD:270247	82/346 (24%)
Tf	NP_001013128.1	PBP2_transferrin_N	24..346	CDD:270336	83/388 (21%)
		PBP2_transferrin_C	357..682	CDD:270335	83/351 (24%)