Protein Alignment Tsf3 and Ltf

DIOPT Version :10

• Sequence 1: NP_523759.1
• Gene: Tsf3 / 36800
• FlyBaseID: FBgn0034094
• Length: 714
• Species: Drosophila melanogaster
• Sequence 2: NP_032548.2
• Gene: Ltf / 17002
• MGIID: 96837
• Length: 707
• Species: Mus musculus
• Alignment Length: 751
• Identity: 167/751 - (22%)
• Similarity: 274/751 - (36%)
• Gaps: 181/751 - (24%)

  Fly    32 LRVCVVESRGVYRKTPKFCPLLEAKSNIE---CV--------IGVDRLDCVRRIHKGTAHFGVLT 85
            |.:|:.::     .|.::|    |.||.|   |:        :|...|.||::.........::|
Mouse    14 LGLCLAKA-----TTVQWC----AVSNSEEEKCLRWQNEMRKVGGPPLSCVKKSSTRQCIQAIVT 69

  Fly    86 SE-DLVA---------------ARWASVEILVASEL-RSHESHFEYEIVAVVDNHANIHTVHDLR 133
            :. |.:.               .|..:.|:....|. |:|     |..||||.|.:|.| ::.|:
Mouse    70 NRADAMTLDGGTMFDAGKPPYKLRPVAAEVYGTKEQPRTH-----YYAVAVVKNSSNFH-LNQLQ 128

  Fly   134 GARLCHPGYGLGNHW---TEVLANYFEAAMVSKTCDPEMTVTEDRIASTAKYFGPSCKAGPWVPD 195
            |.|.||.|.|....|   ...|..|.      ....|..::.|    :.:|:|..||     ||.
Mouse   129 GLRSCHTGIGRSAGWKIPIGTLRPYL------NWNGPPASLEE----AVSKFFSKSC-----VPG 178

  Fly   196 PKQDRILKNRYPSLCEMC--YEPDSCDQT--DKHWGRRGALYCLTSGGGNVAWARLDDVRSHFGF 256
            .::|     |:|:||..|  ...:.|..:  :.:.|..|||.||....|:||:.|...|     |
Mouse   179 AQKD-----RFPNLCSSCAGTGANKCASSPEEPYSGYAGALRCLRDNAGDVAFTRGSTV-----F 233

  Fly   257 SGIPAQSNPSDFSYLCPDGHLQPLNASQPCVWVAKPWPVVAARRSHAAQV--------------Q 307
            ..:|.::....:..||||...:|:...:.|.....|...|.:|.::..:.              :
Mouse   234 EELPNKAERDQYKLLCPDNTWKPVTEYKECHLAQVPSHAVVSRSTNDKEEAIWELLRQSQEKFGK 298

  Fly   308 RLVTGLNHDEPDSWQNALLSLLETYHVFTVPLDNVIAIDDYLDQATAFQSAYSFPECNPPRS--- 369
            :..:|.......|.|..||..........||  ..:.:..||    .|....|....|..:.
Mouse   299 KQASGFQLFASPSGQKDLLFKESAIGFVRVP--QKVDVGLYL----TFSYTTSIQNLNKKQQDVI 357

  Fly   370 -----IVFCTTSIIQHIKCSWLQEASQVYGVQPNIQCVRTMDEQQCLDNTKFKETDVVLVDQEMR 429
                 :.:|.....:..||.....||     :..:.|:.....:.|:......:.|.:.:|....
Mouse   358 ASKARVTWCAVGSEEKRKCDQWNRAS-----RGRVTCISFPTTEDCIVAIMKGDADAMSLDGGYI 417

  Fly   430 VKAQRDYNLVPLLYE-------FAADMHDR----YVTIALVHK-DAKFESFRDLKGARACLPSFE 482
            ..|.: ..|||:|.|       ...|..:|    |:.:|.|.: ||.| ::..|:|.::|
Mouse   418 YTAGK-CGLVPVLAENQKSSKSNGLDCVNRPVEGYLAVAAVRREDAGF-TWSSLRGKKSC----- 475

  Fly   483 GAAHLSVQET---------IVNATGKVQSLHSYFHRDS-------------CLWNLQSGRKCPLH 525
               |.:|..|         :.|.|...: .:.:|.:..             |:.:.:...||..:
Mouse   476 ---HTAVDRTAGWNIPMGLLANQTRSCK-FNEFFSQSCAPGADPKSNLCALCIGDEKGENKCAPN 536

  Fly   526 ----YQGDEGALRCLSEGA-DVAFLSSDVYKKYVVGNLTSNWLTPGNHKDFRVLCPYGGIEKRSN 585
                |||..||||||:|.| :||||......:...|..|..|......|||.:||.....:..:.
Mouse   537 SKERYQGYTGALRCLAEKAGNVAFLKDSTVLQNTDGKNTEEWARNLKLKDFELLCLDDTRKPVTE 601

  Fly   586 FEYCYLHWTTRGHLMTHNSSLTRRNE----IYNSLRDMDQLFGRKYKSETRPFTLYGIFDKRNNV 646
            .:.|:|       .:..|.::..|.:    :...|.|....|||..:.....|.|:.  .|..|:
Mouse   602 AKNCHL-------AIAPNHAVVSRTDKVEVLQQVLLDQQVQFGRNGQRCPGEFCLFQ--SKTKNL 657

  Fly   647 LFRDDTDGLLGLQELHRDNAKRVMEHIYDRYANTQY 682
            ||.|:|:.|          ||...:...::|...:|
Mouse   658 LFNDNTECL----------AKIPGKTTSEKYLGKEY 683

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsf3	NP_523759.1	PBP2_transferrin	33..368	CDD:270247	86/383 (22%)
		PBP2_transferrin	369..681	CDD:270247	79/362 (22%)
Ltf	NP_032548.2	Transferrin	24..351	CDD:395328	83/367 (23%)
		PBP2_transferrin_C	361..691	CDD:270335	80/358 (22%)