DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tsf3 and LOC100498607

DIOPT Version :9

Sequence 1:	NP_523759.1	Gene:	Tsf3 / 36800	FlyBaseID:	FBgn0034094	Length:	714	Species:	Drosophila melanogaster
Sequence 2:	XP_031748086.1	Gene:	LOC100498607 / 100498607	-ID:	-	Length:	749	Species:	Xenopus tropicalis

Alignment Length:	825	Identity:	183/825 - (22%)
Similarity:	285/825 - (34%)	Gaps:	225/825 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MQWLTLILVGLFASFLSISMCVAVQPPDDGKLRVCV---VESR---GVYRKTPKFCPLLEAKSNI 59
            :.:.||:...:|  ||   :.:....|...|.|.|.   :|.|   .:.|......|...|.|.:
Frog     3 LAFCTLLSTNVF--FL---LFMLPHTPSGKKFRWCTLSDLEQRKCSHLARTLQTILPASHAFSRV 62

  Fly    60 ECVIGVDRLDCVRRIHKGTAHFGVLTSEDLVAARWASVEILVASELRSHESHFEYEIVAVVDNHA 124
            .||......||:.:|....|....|.:.|:..| ....::.|.::.|..:....|.:........
Frog    63 SCVRAHTTQDCMSKIRGNKADAVSLDAGDVYTA-IKQYDLAVVAKERHSDGSCVYAVAVARRGTL 126

  Fly   125 NIHTVHDLRGARLCHPGYGLGNHW--------TEVLANYFEAAMVSKTCDPEMTVTEDRIASTAK 181
            ||   |.|...|.||.|....:.|        ::.|.::.|...:||.              .:.
Frog   127 NI---HKLNRTRSCHNGARWTSGWNIPFGFFLSKNLLHWDEEQPLSKV--------------VSA 174

  Fly   182 YFGPSCKAGPWVPDPKQDRILKNRYPSLCEMCYEPDS--------CD--QTDKHWGRRGALYCLT 236
            ||..||..|..:..           |:|||:|....|        |:  ..:......||..||.
Frog   175 YFNASCIPGIGIAS-----------PNLCELCQGSKSYVRDRNNFCEISSNEPFADSDGAFRCLK 228

  Fly   237 SGGGNVAWARLDDVRSHFGFSGIPAQSNPSDFSYLCPDGHLQPLNASQPCVWVAKPWPVVAARRS 301
            :|||:||:      ..|.... .|.:|...:|..|||||....|::.|.|.....|...:.. |.
Frog   229 NGGGDVAF------MDHLAIM-TPTESEMQEFELLCPDGSTANLSSFQYCNLGQGPGKAIVT-RG 285

  Fly   302 HAAQVQR--LVT-----GLNHDE----------PDSWQNALLSLLETYHVFTVPL---------D 340
            |..:|.:  ||.     ||...|          |...||.:      :|..|:.|         .
Frog   286 HLHRVTKRFLVLIQDLFGLKRKEKRRFSLFSSLPFGGQNLM------FHDSTLELQILGNEADVS 344

  Fly   341 NVIAIDDYLDQATAFQSAYSFPECNPPRSIV-FCTTSIIQHIKC-SWLQEASQVYGVQPNIQCVR 403
            :|:.: ||:    |..........:...|:: :|..|..:..|| .|......    .| :.|:.
Frog   345 SVLGM-DYV----ALLKGLGHEGISLDHSVIRWCCISTAELQKCEDWAMNVKS----DP-LVCIL 399

  Fly   404 TMDEQQCLDNTKFKETDVVLVDQEMRVKAQRDYNLVPLLYEFAADMH----DRY----------- 453
            |.....|::..|..|.|.|.:|......|.: ..|.|...|:...:.    |.|
Frog   400 TTSLTGCIEMIKRNEADAVSLDATHAYIAAK-CGLQPAAVEYWGHVSECPTDPYQMPLNITEKGF 463

  Fly   454 ---VTIALVHKDAKFESFRDLKGARAC---LPSFEGAAHLSVQETI-----------VNATGKVQ 501
               ..:|:..|..:..|...:...|:|   :.|..|...|| :.|:           :|:..|
Frog   464 PTLFALAVTKKSNRAVSLSGMSSRRSCHGNIYSVAGWLLLS-KYTVRGNKNDTWDCDINSAYK-- 525

  Fly   502 SLHSYFHRDSCL-------------W---NLQSGRKCPLH---YQGDEGALRCL---SEG---AD 541
               :||.: .|:             |   :...||....|   |.|:.||||||   .||   .|
Frog   526 ---NYFWK-GCMPGAEHNLCKVCIGWEEGDRLMGRCTANHKERYYGNPGALRCLVGDPEGRSFGD 586

  Fly   542 VAFLSSDVYKKYVVGNLTSNWLTPGNHKDFRVLCPYGGIEKRSNFEYCYLHWTTRGHLMTHNSSL 606
            ||||......:.:....:|.|....:..||.:|||.......:::..|.|.......:|| ...:
Frog   587 VAFLEHHSLLENIENLESSGWAHGFSASDFELLCPDESRAALTDWHNCNLGTVPPNVVMT-RPII 650

  Fly   607 TRRNEIYN-SLRDMD----------QLF-GRKYKSETRPFTLYGIFDKRNNVLFRDDTDGL---- 655
            |.:  ||: .::..|          ||| .||         :||    ..::||:|.|..|
Frog   651 TAK--IYDFIIKSQDGLRPEKGSDFQLFQSRK---------IYG----EGDLLFKDSTTCLLPAS 700

  Fly   656 -LGLQELHRDNAKRVMEHIY-----------------DRYANTQY 682
             |.||||..::..::.:.::                 |...:|||
Frog   701 HLRLQELLGESFIQLADSVFKCTQSAILDFCKTDICADPINSTQY 745

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tsf3	NP_523759.1	PBP2_transferrin	33..368	CDD:270247	85/384 (22%)
		PBP2_transferrin	369..681	CDD:270247	88/404 (22%)
		TR_FER	370..656	CDD:214514	81/361 (22%)
LOC100498607	XP_031748086.1	TR_FER	30..358	CDD:214514	85/375 (23%)
LOC100498607	XP_031748086.1	TR_FER	370..713	CDD:214514	86/371 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D125278at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010