DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG44243 and lipt1

DIOPT Version :9

Sequence 1:	NP_001188958.1	Gene:	CG44243 / 36795	FlyBaseID:	FBgn0265178	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	NP_001068570.1	Gene:	lipt1 / 334494	ZFINID:	ZDB-GENE-060929-112	Length:	372	Species:	Danio rerio

Alignment Length:	392	Identity:	140/392 - (35%)
Similarity:	207/392 - (52%)	Gaps:	77/392 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 MLLRRN------SSQLRLLLSSAAQATRLASSGVEPPSAGQQEIKKQRRQPPPVVPDSEIKKSVF 61
            |:||.:      |..:||..:.|:....|..||:                             :.
Zfish     1 MILRLSSRACVLSGSVRLKSTLASFFDDLGKSGI-----------------------------IL 36

  Fly    62 ISQSSDVFTNLALEDWLYKNFDFSRHHVLLLWANDPCVVIGRHQNPFTEANVSQLVERGITLARR 126
            .|.||.:|.|||||||::.:.|.....:||||.|.|.|||||||||:.|.|:......||.||||
Zfish    37 KSASSGIFENLALEDWIHDHVDLQNRSLLLLWRNSPVVVIGRHQNPWQECNLPATRRLGIPLARR 101

  Fly   127 NSGGGAVYHDLGNLNCTFFSPRERYDRKYNLNIVTRALFREWAIKAEIN----ERDDIVVM-NKK 186
            .||||.|:||.||:|.|||:.:::|||..||.:||.||   .|::..::    :|.||::. :.|
Zfish   102 RSGGGTVFHDFGNINMTFFTSKKKYDRHRNLKVVTSAL---KALRPNLDVAATDRFDILLNGHYK 163

  Fly   187 ISGTAAKLGHPNSYHHCTILASANKLHLGESLVREPANYI-SKATASVPSPIRNLVDVNRTVNVA 250
            |||||||||..::|||||:|.|.::..|...|....|..| |.||.|||||::||::|:.|.:.:
Zfish   164 ISGTAAKLGRSSAYHHCTLLCSVDRSVLSSVLKSNTAEVIKSNATPSVPSPVKNLLEVDPTFDSS 228

  Fly   251 QLRSAVGYEYLRTAATTLEDGGSTQTMQQRGFQ----LVNPT-EKWFPGIEELRSNYSSWDWVIG 310
            .:..|:..:|                ..:.||.    .|:|| |...|||.::..:..:|:|:.|
Zfish   229 TIMEAIASQY----------------NSEFGFDSPVITVDPTHEALMPGIHKMAHDLQTWEWIYG 277

  Fly   311 KTPKFTVQKELEVKGDEQDMKLKLSVEVEAGLMKEIGIQLPQSDQLVP-----VVTPLQGKPY-- 368
            |||||:|...|.|    .|:.:||.::|..|.::...:::| :|.|.|     :::.|:|..|
Zfish   278 KTPKFSVCTALVV----DDVNIKLDMDVRNGTVERCALEIP-ADWLSPEIVNELISTLKGSRYCP 337

  Fly   369 NE 370
            ||
Zfish   338 NE 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG44243	NP_001188958.1	LplA	63..311	CDD:223173	107/258 (41%)
CG44243	NP_001188958.1	lipoyltrans	60..380	CDD:161920	130/329 (40%)
lipt1	NP_001068570.1	lipoyltrans	33..335	CDD:161920	128/354 (36%)
lipt1	NP_001068570.1	LplA	44..278	CDD:223173	104/252 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580791
Domainoid	1	1.000	216	1.000	Domainoid score	I2640
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H50569
Inparanoid	1	1.050	217	1.000	Inparanoid score	I3583
OMA	1	1.010	-	-		QHG54427
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003725
OrthoInspector	1	1.000	-	-		oto39050
orthoMCL	1	0.900	-	-		OOG6_101366
Panther	1	1.100	-	-	LDO	PTHR12561
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R663
SonicParanoid	1	1.000	-	-		X3085
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	12.930