Protein Alignment caly and bap1

DIOPT Version :10

• Sequence 1: NP_611096.1
• Gene: caly / 36794
• FlyBaseID: FBgn0262166
• Length: 471
• Species: Drosophila melanogaster
• Sequence 2: NP_001157309.1
• Gene: bap1 / 558885
• ZFINID: ZDB-GENE-050208-492
• Length: 755
• Species: Danio rerio
• Alignment Length: 794
• Identity: 217/794 - (27%)
• Similarity: 291/794 - (36%)
• Gaps: 409/794 - (51%)

  Fly    45 GWLELESDPGLFTLLLKDFGCHDVQVEEVYDLQKPIESP-YGFIFLFRWIEERRARRKIVETTAE 108
            |||||||||||||||::|||...|||||:||||...:|| |||||||:||||||:|||:.....|
Zfish     4 GWLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQSPVYGFIFLFKWIEERRSRRKVSTLVDE 68

  Fly   109 IFVKDEEAISSIFFAQQVVPNSCATHALLSVLLNCNENNLQLGDTLSRLKTHTKGMSPENKGLAI 173
            ..|.|::.::.:|||.|::||||||||||||||||  :.::||.||||:|..|||.:||:||.||
Zfish    69 TSVIDDDIVNDMFFAHQLIPNSCATHALLSVLLNC--SGVELGMTLSRMKAFTKGFNPESKGYAI 131

  Fly   174 GNTPELACAHNSHAMPQARRRLERTGAGVSSCRFTGEAFHFVSFVPINGQLFELDGLKPYPMNHG 238
            ||.||||.||||||.|:.|...|:.. |:|:.| |.|||||||:|||..:||||||||.||::||
Zfish   132 GNAPELAKAHNSHARPEPRHLPEKQN-GISAVR-TMEAFHFVSYVPIKDRLFELDGLKAYPIDHG 194

  Fly   239 GWEDSEDWTDKFRRVMAERLGIAT-GE--QDIRFNLMAVVPDRRIAITHKLKMLRTNQAIVSGTL 300
            .|.:.|:||||.|||:.||:|:|| ||  .|||||||||||||||....||.:|:.|:.|:...|
Zfish   195 PWGEDEEWTDKARRVIMERIGLATAGEPYHDIRFNLMAVVPDRRIKYESKLDILKRNRQIILEGL 259

  Fly   301 QKL-------------------------------------------------------------- 303
            |::
Zfish   260 QQIREKKVIRMTQQESGQDRKQQDSSSSEDTPPVVKKEEVQETPIPSGAEQATPTETQEGAASLP 324

  Fly   304 ----------------------------------------------------------------- 303
                                                                             
Zfish   325 SPAGKVRSMAKPALPAGGAPPPAPLPAPSTNTIVQRLPAFLDNHNYAKSPMQEEEDLAAGVGRSR 389

  Fly   304 ----------------------------------------------------------------- 303
                                                                             
Zfish   390 PPQPPYSDDEDDYDDEEEECSTAGVTNSRVRRKLGLRTRTMSRTAVGGVAAMEGQLALSVLAEKL 454

  Fly   304 ----------------------------------------------------------------- 303
                                                                             
Zfish   455 KKEVQRKDALATTGSTPLNVRTEGRTGGISITSACQPSPTPSNESTDTASEIGSAFNSPLRSPAR 519

  Fly   304 ----------------------------------------------------------------- 303
                                                                             
Zfish   520 SQATTRPSSPVASHVGRVLFGEEEGLPRLDARHNRAVRDLGVLVSSTQLQLQEDGVIFALPPTEA 584

  Fly   304 ----------------------------------LKADEQGESGNGDSQRPDTPTTLLEPSA--- 331
                                              :||::..||.:...::.:.|||.:|.|.
Zfish   585 LEGLKKVGGVDKKKKEEASGPGGEEEVKEGPSVEMKAEDVKESVDVKPEKENLPTTDVENSTKPP 649

  Fly   332 ---FTARDLQSLLKNLDTEIAINEQHLADENDRRHMFKVDASRRTHNYDKFICTFLSMLAHQGVL 393
               :|.::|.:|||.::.:||..|.:|.:|.::|..:|:|..|||||||:|||||:||||.:|:|
Zfish   650 GEKYTPKELLALLKYVEADIANYEVYLKEEVEKRKKYKIDDQRRTHNYDEFICTFISMLAQEGML 714

  Fly   394 GELVSQHLLPSKKVSGQGAA-NRISKQSTTASAGGSTAAGTASTPKTQQQQAAAAKNGKSPSKTP 457
            ..||.|::...::   ||.: .|:.||                                   :.|
Zfish   715 ASLVEQNISVRRR---QGVSIGRLHKQ-----------------------------------RKP 741

  Fly   458 GRRRKGRNKCRKRK 471
            .||::.|....||:
Zfish   742 DRRKRSRPYKAKRQ 755

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
caly	NP_611096.1	Peptidase_C12_UCH37_BAP1	46..274	CDD:187738	147/231 (64%)
		UCH_C	348..393	CDD:465622	25/44 (57%)
bap1	NP_001157309.1	Peptidase_C12_UCH37_BAP1	5..233	CDD:187738	147/231 (64%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	270..354		0/83 (0%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	368..415		0/46 (0%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	469..535		0/65 (0%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	593..652		9/58 (16%)
		UCH_C	669..714	CDD:465622	25/44 (57%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	729..755		9/60 (15%)
		Nuclear localization signal. /evidence=ECO:0000250|UniProtKB:Q92560	743..748		2/4 (50%)