DRSC/TRiP Functional Genomics Resources

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Protein Alignment: CG8435 and CCDC130

Sequence 1:NP_611092.2 Gene:CG8435 FlyBaseID:FBgn0034084 Length:333 Species:Drosophila melanogaster
Sequence 2:NP_001307490.1 Gene:CCDC130 HGNCID:28118 Length:396 Species:Homo sapiens

Alignment Length:411 Identity:109/412 (26%)
Similarity:167/412 (41%) Gaps:95/412 (23%)


  Fly     1 MSERKVLNKYYPPDFDPSKIPRMKLAKNRQYT-----------------VRLMAPFNMRCKTCGE 48
            |.|||.:||||||||:|.|...:    ||.:.                 :|...|:|:.|..|..
Human     1 MGERKGVNKYYPPDFNPEKHGSL----NRYHNSHPLRERARKLSQGILIIRFEMPYNIWCDGCKN 61

  Fly    49 YIYKGKKFNARKEDVENETYLGIRIYRFYIKCTRCLQEISFKTDPQNTDYEIEAGATRNFMALKL 113
            :|..|.::||.|:.|.|  |....||||.:||..|:..|..:|||.|.||.|.:||.|......:
Human    62 HIGMGVRYNAEKKKVGN--YYTTPIYRFRMKCHLCVNYIEMQTDPANCDYVIVSGAQRKEERWDM 124

  Fly   114 AE-EQARREEQELRDEEANNPMKLLEN-RTQQS--RNEIETIESLEELRDLNRRQQTVDYNTLLQ 174
            |: ||....|.|.:.:...:.|..||: ...:|  :..:.|:..::|.:  :..:.....|::|:
Human   125 ADNEQVLTTEHEKKQKLETDAMFRLEHGEADRSTLKKALPTLSHIQEAQ--SAWKDDFALNSMLR 187

  Fly   175 QYNTVETERERQEREEREDEDFIK-SVNFKNKPEGSSRVVAEEIIEEIKDEPLDT---------- 228
            : ...|.::..||.|||:.....| |:.....||...   ..::...:|...||:          
Human   188 R-RFREKKKAIQEEEERDQALQAKASLTIPLVPETED---DRKLAALLKFHTLDSYEDKQKLKRT 248

  Fly   229 --------PSAPPPAKQAKPSTISLSATSSSKASAAQS--------MVKRKTPLVLVKPKATAVA 277
                    ||||..|..:|.|.:......|.:.:.|.|        :|:|::..|   |::...|
Human   249 EIISRSWFPSAPGSASSSKVSGVLKKLAQSRRTALATSPITVGDLGIVRRRSRDV---PESPQHA 310

  Fly   278 KPTVATGTTQVESKPAATTP-SVVSAPAETKAT-----------------------NQPAA---- 314
            ..|..:|..:|..:.|...| |....|.||..|                       :|.||    
Human   311 ADTPKSGEPRVPEEAAQDRPMSPGDCPPETTETPKCSSPRGQEGSRQDKPLSPAGSSQEAADTPD 375

  Fly   315 ----APAGLSLLAAYSDSSED 331
                ...|.||:|.||||..:
Human   376 TRHPCSLGSSLVADYSDSESE 396

Known Domains:


GeneSequenceDomainRegion External IDIdentity
CG8435NP_611092.2 COG5134 7..>170 CDD:227463 54/184 (29%)
DUF572 8..>177 CDD:282371 56/190 (29%)
CCDC130NP_001307490.1 DUF572 8..221 CDD:309584 66/222 (30%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
eggNOG 1 0.900 E1_COG5134
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 1 1.010
OrthoDB 1 1.010 D1583452at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 1 1.030 avgDist Average_Evolutionary_Distance R2441
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
43.950

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