Protein Alignment CG8435 and YJU2

DIOPT Version :10

• Sequence 1: NP_611092.2
• Gene: CG8435 / 36789
• FlyBaseID: FBgn0034084
• Length: 333
• Species: Drosophila melanogaster
• Sequence 2: NP_060544.2
• Gene: YJU2 / 55702
• HGNCID: 25518
• Length: 323
• Species: Homo sapiens
• Alignment Length: 347
• Identity: 177/347 - (51%)
• Similarity: 220/347 - (63%)
• Gaps: 41/347 - (11%)

  Fly     1 MSERKVLNKYYPPDFDPSKIPRMKLAKNRQYTVRLMAPFNMRCKTCGEYIYKGKKFNARKEDVEN 65
            |||||||||||||||||||||::||.|:|||.|||||||||||||||||||||||||||||.|:|
Human     1 MSERKVLNKYYPPDFDPSKIPKLKLPKDRQYVVRLMAPFNMRCKTCGEYIYKGKKFNARKETVQN 65

  Fly    66 ETYLGIRIYRFYIKCTRCLQEISFKTDPQNTDYEIEAGATRNFMALKLAEEQARREEQELRDEEA 130
            |.|||:.|:||||||||||.||:|||||:||||.:|.||||||.|.||.||:.:|.::|..|||.
Human    66 EVYLGLPIFRFYIKCTRCLAEITFKTDPENTDYTMEHGATRNFQAEKLLEEEEKRVQKEREDEEL 130

  Fly   131 NNPMKLLENRTQQSRNEIETIESLEELRDLNRRQQTVDYNTLLQQYNTVETERERQEREEREDED 195
            |||||:|||||:.|:.|:|.:|:|:||:|||:||..||:..:|:|:...|.||.||::||.|.|
Human   131 NNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQE- 194

  Fly   196 FIKSVNFKNKPEGSSRVVAEE-----IIEEIKDEPLDTPSAPPPAKQAKPSTISLSATSSSK--- 252
                          :..:.||     ::|:...|....||...||.:..|:.|...|....:
Human   195 --------------TAALLEEARKRRLLEDSDSEDEAAPSPLQPALRPNPTAILDEAPKPKRKVE 245

  Fly   253 --ASAAQSMVKRK--TPLVLVKPKATAVAKPTVATGTTQVESKPAATTPSVVSAPAETKATNQPA 313
              ..:..|:..|.  :.||:||   .|.|.|..:.|..|     ||.||   .||...|..|...
Human   246 VWEQSVGSLGSRPPLSRLVVVK---KAKADPDCSNGQPQ-----AAPTP---GAPQNRKEANPTP 299

  Fly   314 AAP--AGLSLLAAYSDSSEDSN 333
            ..|  :.||.|.||.| |:|||
Human   300 LTPGASSLSQLGAYLD-SDDSN 320

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8435	NP_611092.2	Saf4_Yju2	9..330	CDD:461333	165/334 (49%)
YJU2	NP_060544.2	Saf4_Yju2	9..318	CDD:461333	166/335 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	207..323		39/126 (31%)