Protein Alignment: CG8435 and YJU2

• Sequence 1: NP_611092.2
• Gene: CG8435
• FlyBaseID: FBgn0034084
• Length: 333
• Species: Drosophila melanogaster
• Sequence 2: NP_060544.2
• Gene: YJU2
• HGNCID: 25518
• Length: 323
• Species: Homo sapiens
• Alignment Length: 347
• Identity: 177/348 (51%)
• Similarity: 220/348 (63%)
• Gaps: 41/348 (12%)

  Fly     1 MSERKVLNKYYPPDFDPSKIPRMKLAKNRQYTVRLMAPFNMRCKTCGEYIYKGKKFNARKEDVEN 65
            |||||||||||||||||||||::||.|:|||.|||||||||||||||||||||||||||||.|:|
Human     1 MSERKVLNKYYPPDFDPSKIPKLKLPKDRQYVVRLMAPFNMRCKTCGEYIYKGKKFNARKETVQN 65

  Fly    66 ETYLGIRIYRFYIKCTRCLQEISFKTDPQNTDYEIEAGATRNFMALKLAEEQARREEQELRDEEA 130
            |.|||:.|:||||||||||.||:|||||:||||.:|.||||||.|.||.||:.:|.::|..|||.
Human    66 EVYLGLPIFRFYIKCTRCLAEITFKTDPENTDYTMEHGATRNFQAEKLLEEEEKRVQKEREDEEL 130

  Fly   131 NNPMKLLENRTQQSRNEIETIESLEELRDLNRRQQTVDYNTLLQQYNTVETERERQEREEREDED 195
            |||||:|||||:.|:.|:|.:|:|:||:|||:||..||:..:|:|:...|.||.||::||.|.|
Human   131 NNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQE- 194

  Fly   196 FIKSVNFKNKPEGSSRVVAEE-----IIEEIKDEPLDTPSAPPPAKQAKPSTISLSATSSSK--- 252
                          :..:.||     ::|:...|....||...||.:..|:.|...|....:
Human   195 --------------TAALLEEARKRRLLEDSDSEDEAAPSPLQPALRPNPTAILDEAPKPKRKVE 245

  Fly   253 --ASAAQSMVKRK--TPLVLVKPKATAVAKPTVATGTTQVESKPAATTPSVVSAPAETKATNQPA 313
              ..:..|:..|.  :.||:||   .|.|.|..:.|..|     ||.||   .||...|..|...
Human   246 VWEQSVGSLGSRPPLSRLVVVK---KAKADPDCSNGQPQ-----AAPTP---GAPQNRKEANPTP 299

  Fly   314 AAP--AGLSLLAAYSDSSEDSN 333
            ..|  :.||.|.||.| |:|||
Human   300 LTPGASSLSQLGAYLD-SDDSN 320

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8435	NP_611092.2	COG5134	7..>170	CDD:227463	119/163 (73%)
		DUF572	8..>177	CDD:282371	120/169 (71%)
YJU2	NP_060544.2	DUF572	8..274	CDD:309584	149/284 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C225873715
eggNOG	1	0.900				E1_COG5134
Hieranoid	1	1.000
Homologene	1	1.000				H6350
Inparanoid	1	1.050	305	1.000	Inparanoid score	I2607
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010				D1583452at2759
OrthoFinder	1	1.000				FOG0004440
OrthoInspector	1	1.000				T1072945
orthoMCL	1	0.900				OOG5_128644
Panther	1	1.100			LDO	PTHR12111
Phylome	1	0.910		0.667	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R2441
TreeFam	1	0.960
User_Submission	0	0.000	Not matched by this tool.
	13	12.790