Protein Alignment CG8435 and YJU2

DIOPT Version :9

• Sequence 1: NP_611092.2
• Gene: CG8435 / 36789
• FlyBaseID: FBgn0034084
• Length: 333
• Species: Drosophila melanogaster
• Sequence 2: NP_060544.2
• Gene: YJU2 / 55702
• HGNCID: 25518
• Length: 323
• Species: Homo sapiens
• Alignment Length: 347
• Identity: 177/347 - (51%)
• Similarity: 220/347 - (63%)
• Gaps: 41/347 - (11%)

  Fly     1 MSERKVLNKYYPPDFDPSKIPRMKLAKNRQYTVRLMAPFNMRCKTCGEYIYKGKKFNARKEDVEN 65
            |||||||||||||||||||||::||.|:|||.|||||||||||||||||||||||||||||.|:|
Human     1 MSERKVLNKYYPPDFDPSKIPKLKLPKDRQYVVRLMAPFNMRCKTCGEYIYKGKKFNARKETVQN 65

  Fly    66 ETYLGIRIYRFYIKCTRCLQEISFKTDPQNTDYEIEAGATRNFMALKLAEEQARREEQELRDEEA 130
            |.|||:.|:||||||||||.||:|||||:||||.:|.||||||.|.||.||:.:|.::|..|||.
Human    66 EVYLGLPIFRFYIKCTRCLAEITFKTDPENTDYTMEHGATRNFQAEKLLEEEEKRVQKEREDEEL 130

  Fly   131 NNPMKLLENRTQQSRNEIETIESLEELRDLNRRQQTVDYNTLLQQYNTVETERERQEREEREDED 195
            |||||:|||||:.|:.|:|.:|:|:||:|||:||..||:..:|:|:...|.||.||::||.|.|
Human   131 NNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQE- 194

  Fly   196 FIKSVNFKNKPEGSSRVVAEE-----IIEEIKDEPLDTPSAPPPAKQAKPSTISLSATSSSK--- 252
                          :..:.||     ::|:...|....||...||.:..|:.|...|....:
Human   195 --------------TAALLEEARKRRLLEDSDSEDEAAPSPLQPALRPNPTAILDEAPKPKRKVE 245

  Fly   253 --ASAAQSMVKRK--TPLVLVKPKATAVAKPTVATGTTQVESKPAATTPSVVSAPAETKATNQPA 313
              ..:..|:..|.  :.||:||   .|.|.|..:.|..|     ||.||   .||...|..|...
Human   246 VWEQSVGSLGSRPPLSRLVVVK---KAKADPDCSNGQPQ-----AAPTP---GAPQNRKEANPTP 299

  Fly   314 AAP--AGLSLLAAYSDSSEDSN 333
            ..|  :.||.|.||.| |:|||
Human   300 LTPGASSLSQLGAYLD-SDDSN 320

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8435	NP_611092.2	COG5134	7..>170	CDD:227463	119/162 (73%)
		DUF572	8..>177	CDD:282371	120/168 (71%)
YJU2	NP_060544.2	DUF572	9..318	CDD:398281	166/335 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	207..323		39/126 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149358
Domainoid	1	1.000	289	1.000	Domainoid score	I1576
eggNOG	1	0.900	-	-		E1_COG5134
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6350
Inparanoid	1	1.050	304	1.000	Inparanoid score	I2656
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1583452at2759
OrthoFinder	1	1.000	-	-		FOG0002595
OrthoInspector	1	1.000	-	-		oto91622
orthoMCL	1	0.900	-	-		OOG6_102870
Panther	1	1.100	-	-	LDO	PTHR12111
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2441
SonicParanoid	1	1.000	-	-		X1951
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.790