DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8435 and cwf16

DIOPT Version :9

Sequence 1:	NP_611092.2	Gene:	CG8435 / 36789	FlyBaseID:	FBgn0034084	Length:	333	Species:	Drosophila melanogaster
Sequence 2:	NP_001342912.1	Gene:	cwf16 / 3361543	PomBaseID:	SPAC9.13c	Length:	270	Species:	Schizosaccharomyces pombe

Alignment Length:	262	Identity:	110/262 - (41%)
Similarity:	150/262 - (57%)	Gaps:	25/262 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSERKVLNKYYPPDFDPSKIPRMKLAK-----NRQYTVRLMAPFNMRCKTCGEYIYKGKKFNARK 60
            ||||||||||.|||:|||..|..|..|     ..:.|||||.||:|||.||||||||||||||||
pombe     1 MSERKVLNKYIPPDYDPSIRPPKKKKKFQGPNGGKLTVRLMTPFSMRCHTCGEYIYKGKKFNARK 65

  Fly    61 EDVENETYLGIRIYRFYIKCTRCLQEISFKTDPQNTDYEIEAGATRNFMAL--KLAEEQARREEQ 123
            |.. .|.|..|.|.||||:||||..||:|.|||::.||..|:||:||:...  |..:|....|..
pombe    66 EKT-GEKYFSIDILRFYIRCTRCAAEITFITDPKHADYAAESGASRNYEPWHEKRLQEYEENELA 129

  Fly   124 ELRDEEANNPMKLLENRTQQSRNEIETIESLEELRDLNRRQQTV---DYNTLLQQ--YNTVETER 183
            |..|....:.|:.||.:|..::.:::..::|:|||:.:.|:..|   |...||::  |.::|.|.
pombe   130 ERNDIPEEDEMEKLEQKTLDTKRQMQISDALDELREKSARRSRVNIDDAIALLKEDAYGSIEEEE 194

  Fly   184 ERQER-EEREDEDFIKSVNFKNKPEGSSRVVAEEIIEEIKDEPLD----------TPSAPPPAKQ 237
            .::.: ||.|.:...||:......|...|:.||..:|:...:|:|          .|:..|| |.
pombe   195 SKKRKFEEEEIDREAKSLFSSQDGEIIRRLNAETTVEKELPKPIDLVSEKLATSNIPNFQPP-KY 258

  Fly   238 AK 239
            ||
pombe   259 AK 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8435	NP_611092.2	COG5134	7..>170	CDD:227463	81/172 (47%)
CG8435	NP_611092.2	DUF572	8..>177	CDD:282371	82/180 (46%)
cwf16	NP_001342912.1	DUF572	8..250	CDD:309584	97/242 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	159	1.000	Domainoid score	I1002
eggNOG	1	0.900	-	-		E1_COG5134
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	174	1.000	Inparanoid score	I1169
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002595
OrthoInspector	1	1.000	-	-		oto102070
orthoMCL	1	0.900	-	-		OOG6_102870
Panther	1	1.100	-	-	LDO	PTHR12111
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2441
SonicParanoid	1	1.000	-	-		X1951
TreeFam	1	0.960	-	-
	12	11.850