Protein Alignment lbk and igfals

DIOPT Version :10

• Sequence 1: NP_611091.2
• Gene: lbk / 36788
• FlyBaseID: FBgn0034083
• Length: 1252
• Species: Drosophila melanogaster
• Sequence 2: XP_003198203.1
• Gene: igfals / 570758
• ZFINID: ZDB-GENE-061009-25
• Length: 614
• Species: Danio rerio
• Alignment Length: 586
• Identity: 151/586 - (25%)
• Similarity: 253/586 - (43%)
• Gaps: 122/586 - (20%)

  Fly   265 CPKDCKC--------LNVLFDCDKLHLERVPV-LPSYVQTLHLANNKLNDTTVLEIRNLLNLTKV 320
            |.|.|.|        |||.  |...:..:||. :|...::|.|..|..::........|.||..:
Zfish    49 CAKGCTCLQDDYSLELNVY--CSTRNFTQVPSDIPLSTRSLWLDGNLFSNLPAGAFEKLTNLEFL 111

  Fly   321 SLKRNLLEVIP--KFIGLSGLKHLVLANNHITSISSESLAALPLLRTLDLSRNKLHTIELNSFPK 383
            :|:.:||..:.  .|.||:.|.||.|..|::.|:|.........|.||.|:.|::..|:...|..
Zfish   112 NLQSSLLVSLDAHAFRGLNSLAHLHLERNNLRSLSGLVFQGTSNLATLSLNNNQMFRIDDRLFAG 176

  Fly   384 SNNLVHLILSFNEITNVNEHSFATLNNLTDLELSNNRLSTLPIRVFKNLNQLKKLALNFNQLEIN 448
            .:::..|.|.:|.::.:.|..|..|:.|.:|.|:.|||:.|..::|:.||:||:|.|..|.|::
Zfish   177 MSHMWLLNLGWNLLSVLPETGFQDLHGLRELILAGNRLAYLQPQLFQGLNELKELDLTGNYLKV- 240

  Fly   449 WSTFRGLESMKNLQLKSNKIRALQDGVFYVMHKIETIDLAMNQISSLSRQGLFNLTKLRHLNLSF 513
                          :|:|        ||..:.|::.:.|..|||.:::.:....:..||.|:||.
Zfish   241 --------------IKAN--------VFLKLPKLQKLYLGQNQIVTVAPRAFVGMKSLRWLDLSR 283

  Fly   514 NAISRIEVDTWEFTQSLEVLDLSNNAINEFKPQHLDCLHRLKTLNLAHNRLQYLQENTFDCVKNL 578
            |.::.:..:|:...|||.||.||||:||..:|.....|..|:.|.|.||:::.|....|:.:.:|
Zfish   284 NRLTVLHDETFIGLQSLHVLRLSNNSINSLRPGTFRDLQYLEELCLYHNQIRALGVRVFEGLGHL 348

  Fly   579 EELNLRRNRLS-----------------------WIIEDQSAAAPFKGLRKLRRLDLHGNNLKQI 620
            |.|||..|||.                       ..:.||    .||||.||..:.|..:.|.::
Zfish   349 EVLNLENNRLQEARMGTFMGLNHLAVMKLTGSCFHSLPDQ----VFKGLSKLHSIHLDRSCLTKV 409

  Fly   621 STKAMSGLNNLEILNLGSNALASIQVNAFEHM-------LRLNKLVFKSLNF---ICDCDLVWFQ 675
            |:::.|||..|..|.|..|.::.::..:|..:       ||.|||...:.|.   :.:.|.:...
Zfish   410 SSQSFSGLTGLRRLFLQHNNISLVERQSFVELQRLQQLDLRFNKLTTITSNTFYGLKNLDYLLLS 474

  Fly   676 QWLKNRFPQQA----EH------------AVCGYPEHLLDRHLKSLSSSELVCVDSP-------- 716
            ..|.:..|.:|    :|            .:.....::|.| |:.|:..:.:.|:.|
Zfish   475 GNLLHNLPAEALLPLQHLSWLDLSGNKLELILNATIYMLPR-LRYLNLKDNILVNLPVSIPESLD 538

  Fly   717 ------------------------KPRVEQEPDDMLAVNAANITLECIASSPTAASLAAADELKI 757
                                    ||:|.....:||.......||..:.::.|.||.::|..|.:
Zfish   539 QLWLSGNNWKCDCSAKPFRDFILQKPQVVPLQVEMLGEGEEPHTLITVYNNVTCASPSSASGLDL 603

  Fly   758 K 758
            :
Zfish   604 R 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbk	NP_611091.2	LRR	<293..642	CDD:443914	110/373 (29%)
		leucine-rich repeat	293..316	CDD:275380	4/22 (18%)
		leucine-rich repeat	317..338	CDD:275380	7/22 (32%)
		leucine-rich repeat	339..362	CDD:275380	7/22 (32%)
		leucine-rich repeat	363..386	CDD:275380	7/22 (32%)
		leucine-rich repeat	387..410	CDD:275380	6/22 (27%)
		leucine-rich repeat	411..434	CDD:275380	9/22 (41%)
		leucine-rich repeat	435..457	CDD:275380	6/21 (29%)
		leucine-rich repeat	458..481	CDD:275380	4/22 (18%)
		leucine-rich repeat	482..505	CDD:275380	4/22 (18%)
		leucine-rich repeat	506..529	CDD:275380	7/22 (32%)
		leucine-rich repeat	530..553	CDD:275380	11/22 (50%)
		leucine-rich repeat	554..577	CDD:275380	7/22 (32%)
		leucine-rich repeat	578..604	CDD:275380	12/48 (25%)
		leucine-rich repeat	607..630	CDD:275380	7/22 (32%)
		leucine-rich repeat	631..652	CDD:275380	5/20 (25%)
		LRRCT	665..712	CDD:214507	9/65 (14%)
		Ig_3	717..816	CDD:464046	12/42 (29%)
		Ig	835..924	CDD:472250
		Ig strand B	851..855	CDD:409353
		Ig strand C	864..868	CDD:409353
		Ig strand E	890..894	CDD:409353
		Ig strand F	904..909	CDD:409353
		Ig strand G	917..920	CDD:409353
		Ig_3	927..1013	CDD:464046
igfals	XP_003198203.1	LRRNT	48..81	CDD:396168	10/33 (30%)
		leucine-rich repeat	65..83	CDD:275380	6/19 (32%)
		leucine-rich repeat	84..107	CDD:275380	4/22 (18%)
		LRR_8	85..142	CDD:404697	17/56 (30%)
		leucine-rich repeat	108..131	CDD:275380	7/22 (32%)
		LRR_8	131..214	CDD:404697	24/82 (29%)
		leucine-rich repeat	132..155	CDD:275380	7/22 (32%)
		leucine-rich repeat	156..203	CDD:275380	13/46 (28%)
		LRR	<196..507	CDD:443914	92/337 (27%)
		leucine-rich repeat	204..227	CDD:275380	9/22 (41%)
		leucine-rich repeat	228..251	CDD:275380	10/45 (22%)
		leucine-rich repeat	252..275	CDD:275380	4/22 (18%)
		leucine-rich repeat	276..299	CDD:275380	7/22 (32%)
		leucine-rich repeat	300..323	CDD:275380	11/22 (50%)
		leucine-rich repeat	324..347	CDD:275380	7/22 (32%)
		leucine-rich repeat	348..369	CDD:275380	8/20 (40%)
		leucine-rich repeat	396..419	CDD:275380	7/22 (32%)
		leucine-rich repeat	420..443	CDD:275380	5/22 (23%)
		leucine-rich repeat	444..467	CDD:275380	6/22 (27%)
		leucine-rich repeat	468..486	CDD:275380	3/17 (18%)
		leucine-rich repeat	492..515	CDD:275380	1/22 (5%)
		leucine-rich repeat	516..540	CDD:275380	4/23 (17%)