Protein Alignment CysRS and cars2

DIOPT Version :9

• Sequence 1: NP_611087.1
• Gene: CysRS / 36784
• FlyBaseID: FBgn0027091
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: XP_682732.4
• Gene: cars2 / 555187
• ZFINID: ZDB-GENE-030131-5564
• Length: 566
• Species: Danio rerio
• Alignment Length: 655
• Identity: 218/655 - (33%)
• Similarity: 311/655 - (47%)
• Gaps: 172/655 - (26%)

  Fly     4 RGQPAWQAPEAVDRPKLKLFNSLTRQKEDFVPLDGNNVTWYSCGPTVYDASHMGHARSYISFDIL 68
            |.:..|..|...| ..:..:||||::||..:.......|||||||||||.:|:|||.||:.||||
Zfish    39 RTERGWVKPVGFD-TGVTAYNSLTKKKEPLILSQEKIATWYSCGPTVYDHAHLGHACSYVRFDIL 102

  Fly    69 RRILSDYFGYNIHYVMNITDIDDKIIRRARQNHLFDEYAAEAQKLPLDELLGQQKEVLQRFQDTC 133
            :||||..||.|:.:||.|||||||||:|:
Zfish   103 QRILSRLFGINVIHVMVITDIDDKIIQRS------------------------------------ 131

  Fly   134 AKNTDPDKKIMLDKTLQRMNDAVEALTKAVGKGDEREISEKRLLYLNEAKDPISDWLDSLKGAQI 198
                                                         |.|...||:
Zfish   132 ---------------------------------------------LEENISPIT----------- 140

  Fly   199 NDNAVFEALPRYWEDQFHNDMKSLNILPPDVLTRVSEYVPQIVTFIQKIIDNGLAY-AANNSVYF 262
                    |.|..|::|..||.:|.:|||.|..||:|.:|||:.||::||.||.|| .:..:|||
Zfish   141 --------LARMHEEEFKKDMLALRVLPPVVYMRVTENIPQIIAFIERIIGNGHAYVTSQGNVYF 197

  Fly   263 DVNGFDKREKHHYAKLVPEAYGDTKSLQEGEGDLSIAEDRLSEKRSANDFALWKASKAGEPWWDS 327
            :.    |...|.|.|||        :|....|     |..:.:|.::.|||||||||..||:|:|
Zfish   198 NT----KSISHRYGKLV--------NLGGNAG-----EQGVQDKENSRDFALWKASKPFEPYWES 245

  Fly   328 PWGKGRPGWHIECSAMASDIFGPTFDIHTGGVDLKFPHHDNELAQSEAAFNESEWVKYFLHTGHL 392
            |||:||||||||||.:||.:||...|||:||:||.||||:||:|||||.....:|..||||:|||
Zfish   246 PWGQGRPGWHIECSTIASSVFGHQLDIHSGGIDLAFPHHENEIAQSEAYHQCEQWGNYFLHSGHL 310

  Fly   393 TIAGC--KMSKSLKNFVTIQEALKKHSATQLRLAFLLHSWKDTLDYSENTMEMATQYEKFLNEFF 455
            .:.|.  ||||||||:|||::.|..::|.:.||..||..::..:|||:.:|..|......::.||
Zfish   311 HLKGSVEKMSKSLKNYVTIKDFLASYTANEFRLFCLLTKYRSAIDYSDASMNEAQSTLSTISAFF 375

  Fly   456 LNVKDLTRHVLSEEPRRQFDAWTEVEAALQKKFSNAQVQVHASLCDNIDTRSALDAIRELVSVSN 520
            .|.:...:..:..:|..:...|        ::.||.|..||..|.|:.||..|:|||..|:...|
Zfish   376 HNAQAYMQGHMQCQPVEEGFLW--------ERLSNTQTSVHKMLADDFDTPKAVDAIMSLIYHGN 432

  Fly   521 VYIRDNKTRLNS----LLLRNVATYITDLLHVFGAISGPRGGIGFPVSGGSGAQAAGADLETTVL 581
            ..::. .|:::.    .:...:.:|:.:::.|||.          .:|..:..|.:...|...
Zfish   433 CQLQP-ATKVDGPRSPAVFGAIMSYVMEIMSVFGV----------DLSDKTEVQVSSGVLNNV-- 484

  Fly   582 PYVQSLAEFRYLVREQAKTLK-----------------------AFDILKLCDDLRDNVLPNLGV 623
              |:.|..||..||:.|.:::                       ...:||.||.||:|:.| |||
Zfish   485 --VEELVHFRSEVRKFALSVEDQAPQESQTGNKNQKRHHQPDRLHLSLLKACDALRNNLAP-LGV 546

  Fly   624 RLEDK 628
            .::|:
Zfish   547 HIKDR 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CysRS	NP_611087.1	PTZ00399	2..737	CDD:240402	218/655 (33%)
		CysRS_core	21..437	CDD:173899	163/418 (39%)
cars2	XP_682732.4	CysS	57..559	CDD:223293	214/636 (34%)
		CysRS_core	57..357	CDD:173899	163/416 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0215
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54140
OrthoDB	1	1.010	-	-		D480663at33208
OrthoFinder	1	1.000	-	-		FOG0000992
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100332
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.730