DRSC/TRiP Functional Genomics Resources

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Protein Alignment CysRS and cars2

DIOPT Version :10

Sequence 1:NP_611087.1 Gene:CysRS / 36784 FlyBaseID:FBgn0027091 Length:741 Species:Drosophila melanogaster
Sequence 2:XP_682732.5 Gene:cars2 / 555187 ZFINID:ZDB-GENE-030131-5564 Length:566 Species:Danio rerio


Alignment Length:655 Identity:218/655 - (33%)
Similarity:311/655 - (47%) Gaps:172/655 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 RGQPAWQAPEAVDRPKLKLFNSLTRQKEDFVPLDGNNVTWYSCGPTVYDASHMGHARSYISFDIL 68
            |.:..|..|...| ..:..:||||::||..:.......|||||||||||.:|:|||.||:.||||
Zfish    39 RTERGWVKPVGFD-TGVTAYNSLTKKKEPLILSQEKIATWYSCGPTVYDHAHLGHACSYVRFDIL 102

  Fly    69 RRILSDYFGYNIHYVMNITDIDDKIIRRARQNHLFDEYAAEAQKLPLDELLGQQKEVLQRFQDTC 133
            :||||..||.|:.:||.|||||||||:|:                                    
Zfish   103 QRILSRLFGINVIHVMVITDIDDKIIQRS------------------------------------ 131

  Fly   134 AKNTDPDKKIMLDKTLQRMNDAVEALTKAVGKGDEREISEKRLLYLNEAKDPISDWLDSLKGAQI 198
                                                         |.|...||:           
Zfish   132 ---------------------------------------------LEENISPIT----------- 140

  Fly   199 NDNAVFEALPRYWEDQFHNDMKSLNILPPDVLTRVSEYVPQIVTFIQKIIDNGLAY-AANNSVYF 262
                    |.|..|::|..||.:|.:|||.|..||:|.:|||:.||::||.||.|| .:..:|||
Zfish   141 --------LARMHEEEFKKDMLALRVLPPVVYMRVTENIPQIIAFIERIIGNGHAYVTSQGNVYF 197

  Fly   263 DVNGFDKREKHHYAKLVPEAYGDTKSLQEGEGDLSIAEDRLSEKRSANDFALWKASKAGEPWWDS 327
            :.    |...|.|.|||        :|....|     |..:.:|.::.|||||||||..||:|:|
Zfish   198 NT----KSISHRYGKLV--------NLGGNAG-----EQGVQDKENSRDFALWKASKPFEPYWES 245

  Fly   328 PWGKGRPGWHIECSAMASDIFGPTFDIHTGGVDLKFPHHDNELAQSEAAFNESEWVKYFLHTGHL 392
            |||:||||||||||.:||.:||...|||:||:||.||||:||:|||||.....:|..||||:|||
Zfish   246 PWGQGRPGWHIECSTIASSVFGHQLDIHSGGIDLAFPHHENEIAQSEAYHQCEQWGNYFLHSGHL 310

  Fly   393 TIAGC--KMSKSLKNFVTIQEALKKHSATQLRLAFLLHSWKDTLDYSENTMEMATQYEKFLNEFF 455
            .:.|.  ||||||||:|||::.|..::|.:.||..||..::..:|||:.:|..|......::.||
Zfish   311 HLKGSVEKMSKSLKNYVTIKDFLASYTANEFRLFCLLTKYRSAIDYSDASMNEAQSTLSTISAFF 375

  Fly   456 LNVKDLTRHVLSEEPRRQFDAWTEVEAALQKKFSNAQVQVHASLCDNIDTRSALDAIRELVSVSN 520
            .|.:...:..:..:|..:...|        ::.||.|..||..|.|:.||..|:|||..|:...|
Zfish   376 HNAQAYMQGHMQCQPVEEGFLW--------ERLSNTQTSVHKMLADDFDTPKAVDAIMSLIYHGN 432

  Fly   521 VYIRDNKTRLNS----LLLRNVATYITDLLHVFGAISGPRGGIGFPVSGGSGAQAAGADLETTVL 581
            ..::. .|:::.    .:...:.:|:.:::.|||.          .:|..:..|.:...|...  
Zfish   433 CQLQP-ATKVDGPRSPAVFGAIMSYVMEIMSVFGV----------DLSDKTEVQVSSGVLNNV-- 484

  Fly   582 PYVQSLAEFRYLVREQAKTLK-----------------------AFDILKLCDDLRDNVLPNLGV 623
              |:.|..||..||:.|.:::                       ...:||.||.||:|:.| |||
Zfish   485 --VEELVHFRSEVRKFALSVEDQAPQESQTGNKNQKRHHQPDRLHLRLLKACDALRNNLAP-LGV 546

  Fly   624 RLEDK 628
            .::|:
Zfish   547 HIKDR 551

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CysRSNP_611087.1 PTZ00399 2..737 CDD:240402 218/655 (33%)
cars2XP_682732.5 None

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