Protein Alignment CysRS and cars1

DIOPT Version :10

• Sequence 1: NP_611087.1
• Gene: CysRS / 36784
• FlyBaseID: FBgn0027091
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: NP_001011365.1
• Gene: cars1 / 496832
• XenbaseID: XB-GENE-5825933
• Length: 747
• Species: Xenopus tropicalis
• Alignment Length: 740
• Identity: 435/740 - (58%)
• Similarity: 531/740 - (71%)
• Gaps: 19/740 - (2%)

  Fly     3 KRGQPAWQAPEAVDRPKLKLFNSLTRQKEDFVPLDGNNVTWYSCGPTVYDASHMGHARSYISFDI 67
            :|.||.|.||....:|.|:|:|||||.||.|||.|||.||||.||||||||||||||||||||||
 Frog    11 RRTQPPWSAPNTQAQPGLRLYNSLTRSKELFVPQDGNKVTWYCCGPTVYDASHMGHARSYISFDI 75

  Fly    68 LRRILSDYFGYNIHYVMNITDIDDKIIRRARQNHLFDEYAAEAQKLPLDELLGQQKEVLQRFQDT 132
            |||:|.|||.|::.|.|||||||||||:||||.|||.:| .|....|.| ||......|..|...
 Frog    76 LRRVLRDYFKYDVFYCMNITDIDDKIIKRARQRHLFQQY-RERNPRPSD-LLQDVSAALTPFLQR 138

  Fly   133 CAKNTDPDKKIMLDKTLQRMNDAVEALTKAVGKGDEREISEKRLLYLNEAK-DPISDWLDSLKGA 196
            .::..||||:.||::....::.|:..|..||......|..|:....|.||. |.:|||||...||
 Frog   139 ISEANDPDKRQMLERIHGSVSAALLPLQDAVSSNARAEELERLSQELMEAAVDLLSDWLDEKHGA 203

  Fly   197 QINDNAVFEALPRYWEDQFHNDMKSLNILPPDVLTRVSEYVPQIVTFIQKIIDNGLAYAANNSVY 261
            ||.||::|..||::||.::|.||::||:||||||||||||||:||.|:|:|:|||..|.:|.|||
 Frog   204 QITDNSIFSQLPKHWESEYHRDMEALNVLPPDVLTRVSEYVPEIVAFVQRIVDNGYGYVSNGSVY 268

  Fly   262 FDVNGFDKREKHHYAKLVPEAYGDTKSLQEGEGDLSIAEDRLSEKRSANDFALWKASKAGEPWWD 326
            |....|...|||:||||||||.||.|:||||||||||:.||||||:|.||||||||||.|||.|:
 Frog   269 FSTAKFHASEKHYYAKLVPEAVGDQKALQEGEGDLSISADRLSEKQSPNDFALWKASKPGEPSWE 333

  Fly   327 SPWGKGRPGWHIECSAMASDIFGPTFDIHTGGVDLKFPHHDNELAQSEAAFNESEWVKYFLHTGH 391
            ||||||||||||||||||..|.|.:.|||.||.||:|||||||||||||.|:...||:|||||||
 Frog   334 SPWGKGRPGWHIECSAMAGSILGESMDIHGGGFDLRFPHHDNELAQSEAYFDNDHWVRYFLHTGH 398

  Fly   392 LTIAGCKMSKSLKNFVTIQEALKKHSATQLRLAFLLHSWKDTLDYSENTMEMATQYEKFLNEFFL 456
            |||||||||||||||:||::||:|::|.|||||||:|:||||||||.||||.|.|||||:|||||
 Frog   399 LTIAGCKMSKSLKNFITIKDALQKNTARQLRLAFLMHAWKDTLDYSSNTMESAVQYEKFMNEFFL 463

  Fly   457 NVKDLTRHVLSEEPRRQFDAWTEVEAALQKKFSNAQVQVHASLCDNIDTRSALDAIRELVSVSNV 521
            |||||.|  ...:...||..|...|..|...|.:.:..||.:||||||||:.::.:|.|||..|.
 Frog   464 NVKDLLR--APTDVTGQFVKWEVPELELNSCFYSKKAAVHEALCDNIDTRTVMEEMRSLVSQCNS 526

  Fly   522 YIRDNKTRL---NSLLLRNVATYITDLLHVFGAISGPRGGIGFPVSGGSGAQAAGADLETTVLPY 583
            ||...|...   |.||||:|::|:|.:|.|||||.|.. .||||:.|...:.    :||:||:||
 Frog   527 YIASRKAAKQPPNRLLLRSVSSYLTAMLKVFGAIEGEE-VIGFPIGGSDNSM----NLESTVMPY 586

  Fly   584 VQSLAEFRYLVREQAKTLKAFDILKLCDDLRDNVLPNLGVRLEDKDIGKYAVKLVDRDSLLRERE 648
            :|.|::||..||:.|:..|..::|:|.|.|||:|||.|||||||.:.....||||||::||:|:|
 Frog   587 LQVLSQFREGVRQIARQHKVTEVLQLSDLLRDDVLPELGVRLEDHEGLPTVVKLVDRETLLKEKE 651

  Fly   649 AKLAAEAEKAAEKE---RKKQAAAEAAAAKEAQRRVNPKEMFLAETEKYSAFDENGLPTHDKEGK 710
            .|..||.||..:||   ||||   :..|||..:.:|:|.:||..||:|||.|||:|.||||.|||
 Frog   652 EKRKAEEEKQRKKEEAARKKQ---QQEAAKLEKMKVSPSQMFQLETDKYSQFDESGFPTHDTEGK 713

  Fly   711 EVSKGQIKKLQKLQQQQEQRYNEYL 735
            |:||||.|||:||.:.||:.:.|||
 Frog   714 ELSKGQSKKLRKLYEAQEKLHKEYL 738

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CysRS	NP_611087.1	PTZ00399	2..737	CDD:240402	435/740 (59%)
cars1	NP_001011365.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..25		6/13 (46%)
		PTZ00399	11..738	CDD:240402	433/738 (59%)
		'HIGH' region	56..66		9/9 (100%)
		'KIIK' region	100..103		2/2 (100%)
		'KMSKS' region	405..409		3/3 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	651..722		40/73 (55%)