Protein Alignment CysRS and cars1

DIOPT Version :10

• Sequence 1: NP_611087.1
• Gene: CysRS / 36784
• FlyBaseID: FBgn0027091
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: NP_001112372.1
• Gene: cars1 / 368284
• ZFINID: ZDB-GENE-030328-29
• Length: 824
• Species: Danio rerio
• Alignment Length: 755
• Identity: 443/755 - (58%)
• Similarity: 544/755 - (72%)
• Gaps: 41/755 - (5%)

  Fly     3 KRGQPAWQAPEAVDRPKLKLFNSLTRQKEDFVPLDGNNVTWYSCGPTVYDASHMGHARSYISFDI 67
            ||.||.|..||..|..||:|:|||||.||.|||..||.|.||.||||||||||||||||||||||
Zfish    90 KRVQPPWSPPEGTDISKLRLYNSLTRTKEVFVPQKGNRVLWYCCGPTVYDASHMGHARSYISFDI 154

  Fly    68 LRRILSDYFGYNIHYVMNITDIDDKIIRRARQNHLFDEYAAEAQKLPLDELLGQQKEVLQ----- 127
            |||||.:||.|::.|.|||||||||||:|||||:|.::|   .:|.|      ...::||
Zfish   155 LRRILKNYFKYDVFYCMNITDIDDKIIKRARQNYLLEQY---REKKP------SAAQILQDVLTA 210

  Fly   128 --RFQDTCAKNTDPDKKIMLDKTLQRMNDAVEA----LTKAV-GKGDEREISEKRLLYLNEAKDP 185
              .|:...|:.||||||.|    |:|::.||:|    |..|| .|..:..|.::..:.|.||||.
Zfish   211 RTPFKAKLAETTDPDKKQM----LERLDSAVDAALGPLQVAVQSKAAQDSIQKQAQVLLEEAKDL 271

  Fly   186 ISDWLDSLKGAQINDNAVFEALPRYWEDQFHNDMKSLNILPPDVLTRVSEYVPQIVTFIQKIIDN 250
            :||||||..|:|:.:|::|..||:|||.::|.||::||:||||||||||||||:||.|::||:||
Zfish   272 LSDWLDSQFGSQVTENSIFSLLPKYWEGEYHKDMEALNVLPPDVLTRVSEYVPEIVEFVKKIVDN 336

  Fly   251 GLAYAANNSVYFDVNGFDKREKHHYAKLVPEAYGDTKSLQEGEGDLSIAEDRLSEKRSANDFALW 315
            |..|.:|.|||||...||....|.||||||||.||.|:||||||||||:.||||||||.||||||
Zfish   337 GYGYESNGSVYFDTAKFDSCPAHSYAKLVPEAVGDQKALQEGEGDLSISADRLSEKRSQNDFALW 401

  Fly   316 KASKAGEPWWDSPWGKGRPGWHIECSAMASDIFGPTFDIHTGGVDLKFPHHDNELAQSEAAFNES 380
            ||||.|||.||||||.|||||||||||||..|.|.:.|||.||.||:|||||||||||||.|...
Zfish   402 KASKPGEPSWDSPWGMGRPGWHIECSAMAGSILGESMDIHGGGFDLRFPHHDNELAQSEAYFEND 466

  Fly   381 EWVKYFLHTGHLTIAGCKMSKSLKNFVTIQEALKKHSATQLRLAFLLHSWKDTLDYSENTMEMAT 445
            .||:||||||||||||||||||||||:||::||.||:|.|||||||:||||||||||.||||.|.
Zfish   467 YWVRYFLHTGHLTIAGCKMSKSLKNFITIKDALAKHTARQLRLAFLMHSWKDTLDYSNNTMESAI 531

  Fly   446 QYEKFLNEFFLNVKDLTRHVLSEEPRRQFDAWTEVEAALQKKFSNAQVQVHASLCDNIDTRSALD 510
            |||:|:|||||||||:.|.  ..:...|::.|...|..|.|.|.:.:..||.:|||||||||||:
Zfish   532 QYERFINEFFLNVKDILRS--PTDITGQYEKWEAEEIELNKCFYDKKTSVHGALCDNIDTRSALE 594

  Fly   511 AIRELVSVSNVYI---RDNKTRLNSLLLRNVATYITDLLHVFGAISGPRGGIGFPVSGGSGAQAA 572
            .:|.||..||.|:   |..|...|.:||:::|.|:||:|..||||.| ...||||| ||:|   .
Zfish   595 EMRALVGQSNTYMAARRSAKLPPNRMLLQSIALYLTDMLKTFGAIEG-TDPIGFPV-GGNG---Q 654

  Fly   573 GADLETTVLPYVQSLAEFRYLVREQAKTLKAFDILKLCDDLRDNVLPNLGVRLEDKDIGKYAVKL 637
            .||||:||:||:..|::||..||:.|:..|..::|:|||.|||:.||.|||||||:|....:|||
Zfish   655 SADLESTVMPYLSVLSDFREDVRKIAREKKVTELLQLCDQLRDDTLPELGVRLEDRDGLPTSVKL 719

  Fly   638 VDRDSLLREREAKLAAEAEKAAEKE---RKKQAAAEAAAAKEAQRRVNPKEMFLAETEKYSAFDE 699
            ||:::||:|:|.|...:.:|..:||   ||||   |...||.|:.::.|.|||.:||:|||:|||
Zfish   720 VDKETLLKEKEEKKKLKDDKRKKKEEAARKKQ---EQEMAKLAKMKLKPSEMFRSETDKYSSFDE 781

  Fly   700 NGLPTHDKEGKEVSKGQIKKLQKLQQQQEQRYNEYLASIE 739
            .|.||||.||||:|||..|||:||.:.||:.:||||.|.:
Zfish   782 TGFPTHDAEGKELSKGLTKKLRKLYETQEKLHNEYLQSTQ 821

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CysRS	NP_611087.1	PTZ00399	2..737	CDD:240402	442/751 (59%)
cars1	NP_001112372.1	GST_C_CysRS_N	2..74	CDD:198343
		PTZ00399	85..822	CDD:240402	443/755 (59%)