Protein Alignment CysRS and CysRS-m

DIOPT Version :9

• Sequence 1: NP_611087.1
• Gene: CysRS / 36784
• FlyBaseID: FBgn0027091
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: NP_001286405.1
• Gene: CysRS-m / 36563
• FlyBaseID: FBgn0033900
• Length: 558
• Species: Drosophila melanogaster
• Alignment Length: 671
• Identity: 209/671 - (31%)
• Similarity: 316/671 - (47%)
• Gaps: 162/671 - (24%)

  Fly     3 KRGQP-AWQAPEAVDRPKLKLFNSLTRQKEDFVPLDGNNVTWYSCGPTVYDASHMGHARSYISFD 66
            |:..| .|:.|.. ....:.::|...|||...:..:...||||:|||||||::|:|||.:|:..|
  Fly    31 KQDSPFKWRKPIG-QHTGINIYNHGLRQKVPLILRNPQMVTWYTCGPTVYDSAHLGHASTYVKVD 94

  Fly    67 ILRRILSDYFGYNIHYVMNITDIDDKIIRRARQNHLFDEYAAEAQKLPLDELLGQQKEVLQRFQD 131
            ||:|||.|||..|:...|||||:|||||:||                   :|.|
  Fly    95 ILQRILRDYFKINLVTAMNITDVDDKIIKRA-------------------QLAG----------- 129

  Fly   132 TCAKNTDPDKKIMLDKTLQRMNDAVEALTKAVGKGDEREISEKRLLYLNEAKDPISDWLDSLKGA 196
                                                                   .||
  Fly   130 -------------------------------------------------------LDW------- 132

  Fly   197 QINDNAVFEALPRYWEDQFHNDMKSLNILPPDVLTRVSEYVPQIVTFIQKIIDNGLAYAA-NNSV 260
                    :.:.|.:|.:|..||..||:..|||.:.|:..:|.|:.|||::||...||.. :|||
  Fly   133 --------QKMARAYEAEFRQDMLRLNVQAPDVRSHVTTTMPVIIQFIQQLIDGKQAYVTPDNSV 189

  Fly   261 YFDVNGFDKREKHHYAKLVPEAYGDTKSLQEGEGDLSIAEDRLSE-KRSANDFALWKASKAG-EP 323
            ||||:     :..:|.||               .:|.::||:|.. ||:..|||||||.|:| ||
  Fly   190 YFDVS-----KSKNYGKL---------------QNLGLSEDKLDPIKRNTADFALWKARKSGSEP 234

  Fly   324 WWDSPW-GKGRPGWHIECSAMASDIFGPTFDIHTGGVDLKFPHHDNELAQSEAAFNESEWVKYFL 387
            .|.:|| |:|||||||||||:|...||...|||.||:||:||||:||.||..|.:...:||.|::
  Fly   235 TWAAPWGGEGRPGWHIECSAIAGLFFGRQLDIHAGGLDLRFPHHENEEAQCCARYKTDQWVNYWV 299

  Fly   388 HTGHLTIAGC--KMSKSLKNFVTIQEALKKHSATQLRLAFLLHSWKDTLDYSENTMEMATQ-YEK 449
            |||.|.:.|.  ||||||.|.:::.|.|||::|.:.|:|.||.::::.:.||:..|..|.| .::
  Fly   300 HTGQLHMVGDREKMSKSLGNTISVSELLKKYTADEFRMACLLSNYRNAMPYSDQLMVTARQTLQR 364

  Fly   450 FLNEFFLNVKDLTRHVLSEEPRRQFDAWTEVEAALQKKFSNAQVQVHASLCDNIDTRSALDA-IR 513
            |.|    ...||:.:....:|....|     |.||:.:.::...:....|.|:.||..|:.. |.
  Fly   365 FRN----FQADLSAYTQFLKPVHLLD-----EGALKAQLTHTVTEFDNCLRDDFDTARAISVLID 420

  Fly   514 ELVSVSNVYIRDNKTRLNSLLLRNVATYITDLLHVFGAISGPRGGIGFPVS---GGSGAQAAGAD 575
            ::.|:|...   |:.::::   :....|..|||...|.... |..:.|.:|   .....|...:.
  Fly   421 QMSSISRCI---NEQQVDA---QEEPAYCIDLLLAAGNFIN-RAIVTFGLSELQDKESLQEKVSF 478

  Fly   576 LETTVLP--YVQSLAEFRYLVREQAKT--LKAFDILKLCDDLRDNVLPNLGVRLEDKDIGK---Y 633
            .:.::.|  .|..:...|..:||:|.:  :|...:|..||:|| ::|...|:::.|...|.   :
  Fly   479 TDHSIDPNLLVNDVINVRGRMRERATSGNVKNPQLLAACDELR-SLLQQHGIQVRDHKQGSSWVF 542

  Fly   634 AVKLVDRDSLLREREAKLAAE 654
            ||....:|.     ::|.:||
  Fly   543 AVSCEKQDD-----KSKSSAE 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CysRS	NP_611087.1	PTZ00399	2..737	CDD:240402	209/671 (31%)
		CysRS_core	21..437	CDD:173899	151/421 (36%)
CysRS-m	NP_001286405.1	CysRS_core	49..351	CDD:173899	151/421 (36%)
		CysS	50..540	CDD:223293	199/626 (32%)
		DALR_2	400..454	CDD:214848	14/59 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45448285
Domainoid	1	1.000	253	1.000	Domainoid score	I63
eggNOG	1	0.900	-	-		E1_COG0215
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D480663at33208
OrthoFinder	1	1.000	-	-		FOG0000992
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100332
Panther	1	1.100	-	-	P	PTHR10890
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.750