Protein Alignment CysRS and Cars2

DIOPT Version :9

• Sequence 1: NP_611087.1
• Gene: CysRS / 36784
• FlyBaseID: FBgn0027091
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: XP_006253522.3
• Gene: Cars2 / 361184
• RGDID: 1311612
• Length: 687
• Species: Rattus norvegicus
• Alignment Length: 665
• Identity: 216/665 - (32%)
• Similarity: 308/665 - (46%)
• Gaps: 192/665 - (28%)

  Fly     1 MSKRGQPAWQAPEAVDRPKLKLFNSLTRQKEDFVPLDGNNVTWYSCGPTVYDASHMGHARSYISF 65
            :.:||: |||.|:..| ..:::.||||.:||..:....:.|:||||||||||.:|:|||.||:.|
  Rat   154 LGRRGR-AWQRPQGQD-TGVQVHNSLTGKKEPLIVGRSDAVSWYSCGPTVYDHAHLGHACSYVRF 216

  Fly    66 DILRRILSDYFGYNIHYVMNITDIDDKIIRRARQNHLFDEYAAEAQKLPLDELLGQQKEVLQRFQ 130
            ||:||||:..||.|:...|:|||:|||||:||.:
  Rat   217 DIIRRILTSVFGCNVVMAMSITDVDDKIIKRANE------------------------------- 250

  Fly   131 DTCAKNTDPDKKIMLDKTLQRMNDAVEALTKAVGKGDEREISEKRLLYLNEAKDPISDWLDSLKG 195
                .|..|
  Rat   251 ----MNVSP-------------------------------------------------------- 255

  Fly   196 AQINDNAVFEALPRYWEDQFHNDMKSLNILPPDVLTRVSEYVPQIVTFIQKIIDNGLAYA-ANNS 259
                     .:|...:|::|..||.:|.:|||.|..||:|.:|||::|||.||.:|.||| |..|
  Rat   256 ---------ASLASLFEEEFKQDMAALKVLPPTVYLRVTENIPQIISFIQGIIAHGHAYATATGS 311

  Fly   260 VYFDVNGFDKREKHHYAKL---VPEAYGDTKSLQEGEGDLSIAEDRLSEKRSANDFALWKASKAG 321
            ||||:..  :.:|  |.||   ||.|..:.            |.|  |:||.::||||||.:|..
  Rat   312 VYFDLRA--RGDK--YGKLVNTVPSATAEP------------AVD--SDKRHSSDFALWKGAKPQ 358

  Fly   322 EPWWDSPWGKGRPGWHIECSAMASDIFGPTFDIHTGGVDLKFPHHDNELAQSEAAFNESEWVKYF 386
            |.:|.||||.||||||||||||||::||...||||||:||.||||:||:||||......:|..||
  Rat   359 EVFWASPWGDGRPGWHIECSAMASEVFGSQLDIHTGGIDLAFPHHENEIAQSEVFHQCQQWGNYF 423

  Fly   387 LHTGHLTIAGC--KMSKSLKNFVTIQEALKKHSATQLRLAFLLHSWKDTLDYSENTMEMATQYEK 449
            ||:|||.:.|.  ||||||||::||::.|:..|....||..|..:::..:|||::|:|.|.....
  Rat   424 LHSGHLHVKGKEEKMSKSLKNYITIKDFLQTFSPDVFRLFCLRTNYRSAIDYSDSTLEEARHLLL 488

  Fly   450 FLNEFFLNVKDLTRHVLSEEPRRQFDAWTEVEAALQKKFSNAQVQVHASLCDNIDTRSALDAIRE 514
            .|..|   |:|...:|     :.|.......|..|.::.::.:..|.|:|.::.||..|:::|.:
  Rat   489 GLASF---VEDARAYV-----KGQLICGPVGEDVLWERLASTKKAVKAALANDFDTPRAVNSILD 545

  Fly   515 LVSVSNVYIRDNKTRLNSLLLRNVATYITDLLHVFGAISGPRGGIGFPVSGG------------- 566
            ||..:|..:|                          |:|...||...|...|
  Rat   546 LVHHANRQLR--------------------------AVSKEAGGPRSPTVFGAIVAYVEQFFETV 584

  Fly   567 ----SGAQAAGADLETTVLP-YVQSLAEFRYLVREQA-------------KTLKAFDILKLCDDL 613
                :..|....|..|..|. .|..|..||..||:.|             :..:...:|:.||.|
  Rat   585 GISLAKRQCVSGDSSTVALHCVVDELVRFRLKVRQYALATPGATGEARKQQLQERQPLLEACDAL 649

  Fly   614 RDNVLPN-LGVRLED 627
            |.:::.: :.|::.|
  Rat   650 RQDLMTHGINVKVSD 664

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CysRS	NP_611087.1	PTZ00399	2..737	CDD:240402	216/664 (33%)
Cars2	XP_006253522.3	PTZ00399	157..664	CDD:240402	215/660 (33%)