Protein Alignment CysRS and Cars1

DIOPT Version :10

• Sequence 1: NP_611087.1
• Gene: CysRS / 36784
• FlyBaseID: FBgn0027091
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: NP_001425105.1
• Gene: Cars1 / 293638
• RGDID: 1310747
• Length: 831
• Species: Rattus norvegicus
• Alignment Length: 746
• Identity: 440/746 - (58%)
• Similarity: 541/746 - (72%)
• Gaps: 19/746 - (2%)

  Fly     3 KRGQPAWQAPEAVDRPKLKLFNSLTRQKEDFVPLDGNNVTWYSCGPTVYDASHMGHARSYISFDI 67
            :|.||.|..|...:..:|:|:|||||.|:.|:|.||..||||.||||||||||||||||||||||
  Rat    95 RRVQPQWSPPAGTEPCRLRLYNSLTRNKDVFIPQDGKKVTWYCCGPTVYDASHMGHARSYISFDI 159

  Fly    68 LRRILSDYFGYNIHYVMNITDIDDKIIRRARQNHLFDEYAAEAQKLPLDELLGQQKEVLQRFQDT 132
            |||:|.|||.|::.|.|||||||||||||||||:||::|  ..||....:||....:.::.|...
  Rat   160 LRRVLRDYFQYDVFYCMNITDIDDKIIRRARQNYLFEQY--REQKPSAAQLLKDVGDAMKPFSVK 222

  Fly   133 CAKNTDPDKKIMLDKTLQRMNDAVEALTKAVGKGDEREISEKRL-LYLNEAKDPISDWLDSLKGA 196
            .::.|||||:.||::....:..|.|.|.:||......|..:.|: :.|.||||.:||||||..|:
  Rat   223 LSETTDPDKRQMLERIQNSVKLATEPLEQAVHSNPSGEEVDSRVQVLLEEAKDLLSDWLDSTGGS 287

  Fly   197 QINDNAVFEALPRYWEDQFHNDMKSLNILPPDVLTRVSEYVPQIVTFIQKIIDNGLAYAANNSVY 261
            ::.||::|..||::||::||.||::||:||||||||||||||:||.|:|||:|||..||:|.|||
  Rat   288 EVTDNSIFSKLPKFWEEEFHKDMEALNVLPPDVLTRVSEYVPEIVNFVQKIVDNGYGYASNGSVY 352

  Fly   262 FDVNGFDKREKHHYAKLVPEAYGDTKSLQEGEGDLSIAEDRLSEKRSANDFALWKASKAGEPWWD 326
            ||...|...|||.|.||||||.||.|:||||||||||:.||||||||.||||||||||.|||.|.
  Rat   353 FDTAKFAASEKHSYGKLVPEAVGDQKALQEGEGDLSISADRLSEKRSPNDFALWKASKPGEPSWP 417

  Fly   327 SPWGKGRPGWHIECSAMASDIFGPTFDIHTGGVDLKFPHHDNELAQSEAAFNESEWVKYFLHTGH 391
            .|||||||||||||||||..:.|.:.|||.||.||:|||||||||||||.|....||:|||||||
  Rat   418 CPWGKGRPGWHIECSAMAGSLLGASMDIHGGGFDLRFPHHDNELAQSEAYFENDCWVRYFLHTGH 482

  Fly   392 LTIAGCKMSKSLKNFVTIQEALKKHSATQLRLAFLLHSWKDTLDYSENTMEMATQYEKFLNEFFL 456
            |||||||||||||||:||::|||||||.|||||||:||||||||||.||||.|.|||||:|||||
  Rat   483 LTIAGCKMSKSLKNFITIKDALKKHSARQLRLAFLMHSWKDTLDYSSNTMESALQYEKFMNEFFL 547

  Fly   457 NVKDLTRHVLSEEPRRQFDAWTEVEAALQKKFSNAQVQVHASLCDNIDTRSALDAIRELVSVSNV 521
            ||||:.|..:  :...||:.|...|..|.|.|.:.:..||.:||||||||:.::.:|.|||..|:
  Rat   548 NVKDILRAPV--DITGQFEKWEAEEVELNKNFYDKKTAVHEALCDNIDTRTVMEEMRALVSQCNL 610

  Fly   522 YIRDNKT---RLNSLLLRNVATYITDLLHVFGAISGPRGGIGFPVSGGSGAQAAGADLETTVLPY 583
            |:...|.   |.|..||.|:|.|:|.:|.:||||. ....:|||| ||.|   ...:||:||:||
  Rat   611 YMAARKAARRRPNRALLENIAMYLTHMLKIFGAIE-EENPLGFPV-GGPG---TNLNLESTVMPY 670

  Fly   584 VQSLAEFRYLVREQAKTLKAFDILKLCDDLRDNVLPNLGVRLEDKDIGKYAVKLVDRDSLLRERE 648
            :|.|:|||..||:.|:..|..::|:|.|.|||::||.||||.||.:.....|||||||:||:|:|
  Rat   671 LQVLSEFREGVRKIAREKKVLEVLQLSDALRDDILPELGVRFEDHEGLPTVVKLVDRDTLLKEKE 735

  Fly   649 AKLAAEAEKAAEKE---RKKQAAAEAAAAKEAQRRVNPKEMFLAETEKYSAFDENGLPTHDKEGK 710
            .|..||.||..:||   ||||   |..|||.|:.:..|.|||.:||:|||.||||||||||.|||
  Rat   736 EKKRAEEEKRRKKEEAARKKQ---EQEAAKLAKMKTPPSEMFRSETDKYSKFDENGLPTHDTEGK 797

  Fly   711 EVSKGQIKKLQKLQQQQEQRYNEYLASIEKA 741
            |:||||.|||:||.:.||:.|.|||..::.:
  Rat   798 ELSKGQTKKLKKLFEAQEKVYKEYLQQLQNS 828

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CysRS	NP_611087.1	PTZ00399	2..737	CDD:240402	440/740 (59%)
Cars1	NP_001425105.1	None