Protein Alignment CysRS and cars2

DIOPT Version :10

• Sequence 1: NP_611087.1
• Gene: CysRS / 36784
• FlyBaseID: FBgn0027091
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: XP_002933053.1
• Gene: cars2 / 100498149
• XenbaseID: XB-GENE-976543
• Length: 572
• Species: Xenopus tropicalis
• Alignment Length: 669
• Identity: 219/669 - (32%)
• Similarity: 312/669 - (46%)
• Gaps: 176/669 - (26%)

  Fly     7 PA--WQAPEAVDRPKLKLFNSLTRQKEDFVPLDGNNVTWYSCGPTVYDASHMGHARSYISFDILR 69
            ||  |..|...| ..:|::|||||:|:..:..|....|||||||||||.:|:|||.||:.|||:|
 Frog    41 PAGCWAPPSGHD-TGIKVYNSLTRRKDPLILADPTVATWYSCGPTVYDHAHLGHACSYVRFDIIR 104

  Fly    70 RILSDYFGYNIHYVMNITDIDDKIIRRARQNHLFDEYAAEAQKLPLDELLGQQKEVLQRFQDTCA 134
            |||...||.:...||.:||||||||:||::.::
 Frog   105 RILLKVFGIDTVVVMVVTDIDDKIIKRAKELNI-------------------------------- 137

  Fly   135 KNTDPDKKIMLDKTLQRMNDAVEALTKAVGKGDEREISEKRLLYLNEAKDPISDWLDSLKGAQIN 199
                                                             .|:
 Frog   138 -------------------------------------------------SPV------------- 140

  Fly   200 DNAVFEALPRYWEDQFHNDMKSLNILPPDVLTRVSEYVPQIVTFIQKIIDNGLAYA-ANNSVYFD 263
                  ||.|.:|..|..||.:|.:|||.|..||:|.:|||::||:.||.||.||| :..:||||
 Frog   141 ------ALARTYEQDFKQDMTALKVLPPTVYMRVTENIPQIISFIEHIIANGYAYATSQGNVYFD 199

  Fly   264 VNGFDKREKHHYAKLVPEAYGDTKSLQEGEGDLSIAEDRLSEKRSANDFALWKASKAGEPWWDSP 328
            |....:|    |.|. .:::.||.|           |....:||...||||||.||..||:|.||
 Frog   200 VQSIGER----YGKF-NDSFSDTAS-----------ESASQDKRHIRDFALWKTSKPEEPYWASP 248

  Fly   329 WGKGRPGWHIECSAMASDIFGPTFDIHTGGVDLKFPHHDNELAQSEAAFNESEWVKYFLHTGHLT 393
            |||||||||||||.:||.:||...||||||:||.||||:||:||.||....::|..||||||||.
 Frog   249 WGKGRPGWHIECSTIASSVFGKHLDIHTGGIDLAFPHHENEIAQCEAYHQSTQWGNYFLHTGHLH 313

  Fly   394 IAGC--KMSKSLKNFVTIQEALKKHSATQLRLAFLLHSWKDTLDYSENTMEMATQYEKFLNEFFL 456
            :.|.  ||||||:|:||::|.||..|..|.|:..|...:|..::||..:|..|......::.|..
 Frog   314 LKGNEEKMSKSLRNYVTVKEFLKSFSPDQFRMFCLRSKYKSAVEYSNGSMHDAVNTLHTISSFVD 378

  Fly   457 NVKDLTRHVLSEEPRRQFDAWTEVEAALQKKFSNAQVQVHASLCDNIDTRSALDAIRELVSVSNV 521
            :.|...:..|..:|.:        ||.|.::.:..:|.|.|:..|:.||..|:||:.:|:...|.
 Frog   379 DAKAYMKGQLICQPVQ--------EALLWQRLNETKVNVKAAFSDDFDTPRAVDAVMDLIHHGNR 435

  Fly   522 YI----RDNKTRLNSLLLRNVATYITDLLHVFGAISGPRGGIGFPVSGGSGAQAAGADLETTVL- 581
            .:    :::.:..:|::...:.:||...|.:.|.             ..|..|.|..|..:.||
 Frog   436 QLKAVSKESNSPRSSVVYGAMISYIEQFLEILGI-------------SLSQNQVAAEDRHSAVLF 487

  Fly   582 PYVQSLAEFRYLVREQAKT------------------------LKAFDILKLCDDLRDNVLPNLG 622
            ..|:.:..||..||..|..                        |:...:|:.||.:|.: |...|
 Frog   488 NVVEEMISFRSKVRNYALAADESPNAIGQEEKQQYKERRRQLLLEREPLLQACDIMRQH-LAVYG 551

  Fly   623 VRLEDKDIGKYAV-KLVDR 640
            :.::|:  |..:. :|:||
 Frog   552 INVKDR--GNTSTWELLDR 568

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CysRS	NP_611087.1	PTZ00399	2..737	CDD:240402	219/669 (33%)
cars2	XP_002933053.1	PTZ00399	23..570	CDD:240402	219/669 (33%)