Protein Alignment Jhe and Ces2f

DIOPT Version :10

• Sequence 1: NP_523758.3
• Gene: Jhe / 36780
• FlyBaseID: FBgn0010052
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_001073334.2
• Gene: Ces2f / 71903
• MGIID: 1919153
• Length: 561
• Species: Mus musculus
• Alignment Length: 559
• Identity: 163/559 - (29%)
• Similarity: 242/559 - (43%)
• Gaps: 108/559 - (19%)

  Fly    58 FMGIPYALPPIGDLRFSNPKVMPKLLGMYDASAPKMDCIQKNYL----------LPTPVVYGDED 112
            |:|||:|.||:|.|||:.|:......|:.|.::....|:|.:.:          :..|.....||
Mouse    60 FLGIPFAKPPVGPLRFAPPEAPEPWSGVRDGTSQPAMCLQNDDIVNLEGLKIIKMILPPFSMSED 124

  Fly   113 CLYLNVYRPEIRK--SALPVMVYIHGGGFFGGSA----GPGVTGPEYFMDSGEVILVTMAYRLGP 171
            |||||:|.|...:  |.|||||::||||...|.|    |..:...|      :|::|...||||.
Mouse   125 CLYLNIYTPAHAQEGSNLPVMVWLHGGGLVAGMASMYDGSVLAATE------DVVVVVTQYRLGI 183

  Fly   172 FGFLSTQDAVMSGNFGLKDQNLALRWVQRNIRFFGGDPQRVTIFGQSAGGVAAHMHLLSPRSHGL 236
            .||.||.|....||:|..||..||.|||:||..|||:|..||:|||||||.:...|:|||.|.||
Mouse   184 PGFYSTGDEQARGNWGFLDQTAALHWVQQNIANFGGNPDSVTLFGQSAGGTSVSFHVLSPVSQGL 248

  Fly   237 FHRVISMSGTANVPFAIAEQPLEQARLLAEFADVPDARNLSTVKLTKALRRINATKLLNAGDGLK 301
            |||.|..||.|.:|..|.:.|   ..:..:.|::......::..|.:.||..:..::|......:
Mouse   249 FHRAIMESGVALLPTIIPDSP---EMIFTKVANLSGCETSNSEALVRCLRGKSEAEILAMSKAFR 310

  Fly   302 YWDVDHMTNFRPVVEEGLEVDAFLNAHPMDMLAQGMPTSIPLLLGTVPGEGAVRVVNILGNETLR 366
                     |.|.|.:|    .||..||..:||......:|.::|          ||
Mouse   311 ---------FMPAVVDG----KFLPRHPKKLLASADFHPVPSIIG----------VN-------- 344

  Fly   367 QSFNLRFDELLQELLEFPASFSQDRR-----------EKMM------DLLVEVYFQGQHEVNELT 414
               |..:..::.::.:|..:..:..|           |:||      |||:|.|.:...:...|.
Mouse   345 ---NDEYGWIIPKIFKFSQTIRKINRNNLKAIMKITTEQMMLPSECGDLLIEEYLRDTEDPWTLQ 406

  Fly   415 VQGFMNLISDRGFKQPLYNTIHKNVCHTPNPVYLYSFNYQGPL--SYASAYTSANVTGKYGVVHC 477
            :| |..:|.|.....|..........|.  |||.|.|.::..|  .:...:..|:        |.
Mouse   407 MQ-FREMIGDFLIIIPALQVARFQRSHA--PVYFYEFQHRSSLLKYFRPWHVKAD--------HG 460

  Fly   478 DDLLYLFRSPLLFPDFQRNSTEAKVIHSFVDYFVHFAKFGKPRNSESLTPCSIEVLQSRPDGICD 542
            |:|..:|.|......|...:.|..:....:.|:.:||::|.| |||.|                .
Mouse   461 DELYLIFGSFFWGLKFSFTAEEKLLSRKMMKYWANFARYGNP-NSEDL----------------P 508

  Fly   543 YHEFANAPDAYQGFEVH--VASEFQTDRVNLWSHILNEK 579
            |...:|..|.|...::|  |....:..|:..|:..|.:|
Mouse   509 YWPASNQDDLYLQLDIHPSVGHALKARRLPFWTKTLPQK 547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhe	NP_523758.3	alpha/beta hydrolases	38..527	CDD:473884	153/503 (30%)
Ces2f	NP_001073334.2	COesterase	32..540	CDD:395084	160/550 (29%)