Protein Alignment Jhe and Aadac

DIOPT Version :10

• Sequence 1: NP_523758.3
• Gene: Jhe / 36780
• FlyBaseID: FBgn0010052
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_065413.1
• Gene: Aadac / 57300
• RGDID: 631440
• Length: 398
• Species: Rattus norvegicus
• Alignment Length: 420
• Identity: 95/420 - (22%)
• Similarity: 158/420 - (37%)
• Gaps: 132/420 - (31%)

  Fly    81 KLLGMYDASAPKMDCIQ---KNYLLP------TPVVYGDEDCLYLNVYRPEIRKSAL-PVMVYIH 135
            :|||:...    ||.:|   :..::|      ..|:..|.:.:.:.:|.|:.:.:.| ..:.:||
  Rat    50 ELLGLNHF----MDTVQLFMRFQVVPPTSDENVTVMETDFNSVPVRIYIPKRKSTTLRRGLFFIH 110

  Fly   136 GGGFFGGSAGPGVTGPEYFMDSGEVILVTMAYRLGPFGFLSTQDA-VMSGNFGL----------K 189
            |||:..|||.       |||  .:.:....|:||         || |:|.::||          :
  Rat   111 GGGWCLGSAA-------YFM--YDTLSRRTAHRL---------DAVVVSTDYGLAPKYHFPKQFE 157

  Fly   190 DQNLALRW-VQRNI-RFFGGDPQRVTIFGQSAGG---VAAHMHLLSPRSHGLFHRVISMSGTANV 249
            |...:||| :|.:| ..:|.||:||.:.|.||||   .|....:|.               ..:|
  Rat   158 DVYHSLRWFLQEDILEKYGVDPRRVGVSGDSAGGNLTAAVTQQILQ---------------DPDV 207

  Fly   250 PFAIAEQPLEQARLLAEFADVPDAR-NLSTVKLTKALRRINATKLLNAGDGLKYWDVDHMTNFRP 313
            ...:..|.|....|.|...:||..: |.....||::|.             :::|. ::.|
  Rat   208 KIKLKVQALIYPALQALDMNVPSQQENSQYPLLTRSLL-------------IRFWS-EYFT---- 254

  Fly   314 VVEEGLEVDAFLNAH-PMD------------MLAQ--------GMPTSIPL-LLGTVPGEGAVRV 356
             .:..||....||.| |::            :|.|        ..||...| |....||...|:.
  Rat   255 -TDRDLEKAMLLNQHVPVEFSHLLQFVNWSSLLPQRYKKGYFYKTPTPGSLELAQKYPGFTDVKA 318

  Fly   357 VNILGNETLRQSFNL------RFDELLQELLEFPASFSQDRREKMMDLLVEVYFQGQHEVNELTV 415
            ..:|.|:::.....:      ::|.|               |:..:..:..:...|.|..:....
  Rat   319 CPLLANDSILHHLPMTYIITCQYDVL---------------RDDGLMYVKRLQNTGVHVTHHHIE 368

  Fly   416 QGFMNLISDRGFK-----QPLY-NTIHKNV 439
            .||...::..|.|     |..| |.:|||:
  Rat   369 DGFHGALTLPGLKITYRMQNQYLNWLHKNL 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhe	NP_523758.3	alpha/beta hydrolases	38..527	CDD:473884	95/420 (23%)
Aadac	NP_065413.1	Abhydrolase_3	106..373	CDD:400284	75/333 (23%)
		Involved in the stabilization of the negatively charged intermediate by the formation of the oxyanion hole. /evidence=ECO:0000250|UniProtKB:Q5NUF3	110..112		1/1 (100%)