Protein Alignment Jhe and ces2a

DIOPT Version :10

• Sequence 1: NP_523758.3
• Gene: Jhe / 36780
• FlyBaseID: FBgn0010052
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_001070720.1
• Gene: ces2a / 566132
• ZFINID: ZDB-GENE-061013-99
• Length: 555
• Species: Danio rerio
• Alignment Length: 556
• Identity: 156/556 - (28%)
• Similarity: 236/556 - (42%)
• Gaps: 120/556 - (21%)

  Fly    23 CAALATVDQLTVCPPS--VGCLKGTNLQG-YQSER-----FEAFMGIPYALPPIGDLRFSNPKVM 79
            |..||.|....|...|  |..||..:::| |...:     .|.::|||:|.||:|..|.:.|:.:
Zfish    10 CLTLAPVWSAPVQEDSGPVAVLKHGSVRGQYVKAKGSPAVVEQYLGIPFAQPPVGPHRLAAPQPV 74

  Fly    80 PKLLGMYDASAPKMDCIQKNYLLP---------TPVVYGDEDCLYLNVYRPEIRKSA--LPVMVY 133
            ....|:.:|:...:.|:|...:||         ...:...|||||||||.|..|..:  ||||::
Zfish    75 QGWEGIRNATEHPLMCLQNPDILPAIAKAIDLEVTAIGVSEDCLYLNVYTPSQRAESEKLPVMIW 139

  Fly   134 IHGGGFFGGSA----------GPGVTGPEYFMDSGEVILVTMAYRLGPFGFLSTQDAVMSGNFGL 188
            |||||...|.|          |..:...|      :|::|.:.||||..|:.||.|....||:|.
Zfish   140 IHGGGLAMGGACMFKELCLYDGTPLAAYE------KVVVVVIQYRLGILGYFSTGDQHAKGNWGF 198

  Fly   189 KDQNLALRWVQRNIRFFGGDPQRVTIFGQSAGGVAAHMHLLSPRSHGLFHRVISMSGTANVPFAI 253
            .||..||:|||:||..||||||.|||.|:||||::|.:..|||.:.|||.|.|..||.|.|....
Zfish   199 LDQIAALQWVQQNIEAFGGDPQSVTIAGESAGGISASLLTLSPMTKGLFQRAIFQSGVATVKGYF 263

  Fly   254 AEQPLEQARLLAEFADVPDARNLSTVKLTKALRRINATKLLNAGDGLKYWDVDHMTNFRPVVEEG 318
            .:.|...|:::   |::.:....|:..|.|.:|.:...:::.|..             :..:..|
Zfish   264 VKDPSTHAQVI---ANITECDFSSSEVLVKCIREMTEEQIIKAAQ-------------KKGIFPG 312

  Fly   319 LEVDA-FLNAHPMDMLAQGMPTSIPLLLGTVPGEGAVRVVNILGNETLRQSFNLRFDELLQELLE 382
            ..||. |:.|.|.::|.......:|:|:||.                     |..|..:|
Zfish   313 AAVDGEFIKAQPEEILKSKDFQKVPILIGTT---------------------NHEFGWML----- 351

  Fly   383 FPASFSQDRREKMMD---------------------LLVEVYFQGQHEVNELTVQGFMNLISDRG 426
             |..|......|.||                     ::.:.||:......|:. ..|..|:.|..
Zfish   352 -PQIFLPKEWVKGMDTKAAKDRLGLLNADGASGANGIIADEYFKNAKTPEEIR-DAFTELLGDIF 414

  Fly   427 FKQPLYN--TIHKNVCHTPNPVYLYSFNYQGPLSYASAYTSANVTGKYGVVHCDDLLYLFRSPLL 489
            ...|...  :.|:   ....|||:|.|.: || |.|:.:..:.|...    |.||:.::|.:  .
Zfish   415 MVIPSITVASYHR---EAGVPVYMYEFQH-GP-STANKFRPSFVKAD----HADDVGFVFGA--C 468

  Fly   490 FPDFQ------RNSTEAKVIHSFVDYFVHFAKFGKP 519
            |.|..      ....|.::..:.:.|..:|.:.|.|
Zfish   469 FWDVHVKGLGTLTEEENQLCRTVMKYRANFIRTGSP 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhe	NP_523758.3	alpha/beta hydrolases	38..527	CDD:473884	151/541 (28%)
ces2a	NP_001070720.1	COesterase	25..541	CDD:395084	151/541 (28%)