Protein Alignment Jhe and nlgn3a

DIOPT Version :10

• Sequence 1: NP_523758.3
• Gene: Jhe / 36780
• FlyBaseID: FBgn0010052
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: XP_005157256.1
• Gene: nlgn3a / 562702
• ZFINID: ZDB-GENE-071219-1
• Length: 878
• Species: Danio rerio
• Alignment Length: 604
• Identity: 158/604 - (26%)
• Similarity: 259/604 - (42%)
• Gaps: 125/604 - (20%)

  Fly    56 EAFMGIPYALPPIGDLRFSNPKVMPKLLGMYDASAPKMDCIQKNY-----------------LLP 103
            :.::|:|||.||:|:.||..|:......|:.:|:.....|.|..:                 ::.
Zfish    94 DQYLGVPYATPPVGEKRFLPPEPPSSWSGIKNATHFAPVCPQNIHNAVPEIMMPIWFTFNLDIVA 158

  Fly   104 TPVVYGDEDCLYLNVYRP-------------------------------------------EIRK 125
            |.:...:|||||||:|.|                                           :||.
Zfish   159 TSIQDQNEDCLYLNIYVPTEDVKRISKECTRKPNKKICRKGGTHSKKQGEDLSDNDGDEDEDIRD 223

  Fly   126 S-ALPVMVYIHGGGFFGGSAGPGVTGPEYFMDSGEVILVTMAYRLGPFGFLSTQDAVMSGNFGLK 189
            : |.|||||||||.:..|: |..:.| ......|.||::|:.:|:|..|||||.|....||:||.
Zfish   224 TGAKPVMVYIHGGSYMEGT-GNMIDG-SVLASYGNVIVITLNFRVGVLGFLSTGDQAAKGNYGLL 286

  Fly   190 DQNLALRWVQRNIRFFGGDPQRVTIFGQSAGGVAAHMHLLSPRSHGLFHRVISMSGTANVPFAIA 254
            ||..||||:..||.:||||..|:|:||...|.....:..||..|.|||||.|..||:|...:|:.
Zfish   287 DQIQALRWISENIGYFGGDSNRITVFGSGIGASCVSLLTLSHHSEGLFHRAIIQSGSALSSWAVN 351

  Fly   255 EQPLEQARLLAEFADVPDARNLSTVKLTKALRRINATKLLNAGDGLKYWDVD----HMTNFRPVV 315
            .||::..|||||..   ....|.|:.:...||:.:|.:|:..       |:.    |:. |.||:
Zfish   352 YQPVKYTRLLAEKV---GCNVLDTLDMVDCLRKKSARELVEQ-------DIQPARYHVA-FGPVI 405

  Fly   316 EEGLEVDAFLNAHPMDMLAQGMPTSIPLLLGTVPGEGAVRVVNILGNE--TLRQSFNLRFDELLQ 378
            :..:..|     .|..::.||...:..::||...|||...|.|::.:|  .....|:....:.:.
Zfish   406 DGDVIPD-----DPEILMEQGEFLNYDIMLGVNQGEGLRFVENVVDSEDGVSGNDFDFSVSDFVD 465

  Fly   379 ELLEFPASFSQDRREKMMDLLVEVYFQGQHEVN-ELTVQGFMNLISDRGFKQPLYNT--IHKNVC 440
            .|..:|     :.::.:.:.:..:|.......| |...:..:.|.:|..:.:|...|  :|   .
Zfish   466 SLYGYP-----EGKDTLRETIKFMYTDWADRDNPETRRKTLVALFTDHQWVEPSVVTADLH---A 522

  Fly   441 HTPNPVYLYSFNYQGPLSYASAYTSANVTGKYGVVHCDDLLYLFRSPL-----LFP-DFQRNSTE 499
            ...:|.|.|:|.:........|::.|        .|.|::.|:|..|:     ||| :|.:|...
Zfish   523 RYGSPTYFYAFYHHCQSLMKPAWSDA--------AHGDEVPYVFGIPMIGPTDLFPCNFSKNDIM 579

  Fly   500 AKVIHSFVDYFVHFAKFGKPRNSESLTPCSIEVLQSRPDGICDYHEFA----NAPD---AYQGFE 557
            ...:  .:.|:.:|||.|.|...   .|...:.:.::.:   .:.|.|    |..|   .:.|.:
Zfish   580 LSAV--VMTYWTNFAKTGDPNKP---VPQDTKFIHTKAN---RFEEVAWSKYNPQDQLYLHIGLK 636

  Fly   558 VHVASEFQTDRVNLWSHIL 576
            ..|...::..:|..|.|::
Zfish   637 PRVRDHYRATKVAFWKHLV 655

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhe	NP_523758.3	alpha/beta hydrolases	38..527	CDD:473884	148/546 (27%)
nlgn3a	XP_005157256.1	COesterase	69..651	CDD:395084	156/598 (26%)