Protein Alignment Jhe and Ces2h

DIOPT Version :10

• Sequence 1: NP_523758.3
• Gene: Jhe / 36780
• FlyBaseID: FBgn0010052
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_001258974.1
• Gene: Ces2h / 436059
• MGIID: 3648740
• Length: 558
• Species: Mus musculus
• Alignment Length: 555
• Identity: 162/555 - (29%)
• Similarity: 251/555 - (45%)
• Gaps: 98/555 - (17%)

  Fly    57 AFMGIPYALPPIGDLRFSNPKVMPKLLGMYDASAPKMDCIQ-------------KNYLLPTPVVY 108
            :|:|||:|.||:|.|||:.|:......|:.|.::....|:|             |..|.|.|:
Mouse    56 SFLGIPFAKPPVGPLRFAPPEPPEPWGGVRDGTSHPAMCLQDITAMNMQAFKLLKLTLPPFPM-- 118

  Fly   109 GDEDCLYLNVYRPE--IRKSALPVMVYIHGGGFFGGSA----GPGVTGPEYFMDSGEVILVTMAY 167
             .|||||||:|.|:  ...|.|||||:||||....|.|    |..:...|      .|::||:.|
Mouse   119 -SEDCLYLNIYAPDHAHEGSNLPVMVWIHGGSLVIGMASMYDGSMLAAME------NVVVVTIQY 176

  Fly   168 RLGPFGFLSTQDAVMSGNFGLKDQNLALRWVQRNIRFFGGDPQRVTIFGQSAGGVAAHMHLLSPR 232
            |||..||.||.|....||:|..||..||||:|:||.:|||:|.||||||.||||.:....::||.
Mouse   177 RLGVLGFFSTGDERARGNWGYLDQVAALRWLQQNIAYFGGNPDRVTIFGTSAGGTSVSSLVVSPM 241

  Fly   233 SHGLFHRVISMSGTANVPFAIAEQPLEQARLLAEFADVPDARNLSTVKLTKALRRINATKLLNAG 297
            |.|||...|..||.|.:           :.|::..:||.    ..||.......::::..|:|..
Mouse   242 SQGLFRGAIMESGVALI-----------SSLISVSSDVV----YQTVANLSGCEQVDSEALVNCL 291

  Fly   298 DGLKYWDVDHMTN-FR--PVVEEGLEVDAFLNAHPMDMLAQGMPTSIPLLLGTVPGEGAVRVVNI 359
            .|....::..:.. |:  |.:.:|:    ||..||.:::|......:|.::|....|....:.:.
Mouse   292 RGKSEEEIMAINKAFKIIPGIVDGI----FLPRHPQELMASADFHPVPSIIGVNNDEYGWIIPSS 352

  Fly   360 LGNETLRQSFNLRFDELLQELLEFPASFSQDRREKMM------DLLVEVYFQGQHEVNELTVQGF 418
            :.....::..:   .:::|.:|       |.|..:||      |||:|.|.....:...|.|| |
Mouse   353 MSMIDSKKGMD---RQMVQAIL-------QRRATQMMWPPEVSDLLMEEYMGDNEDPQFLQVQ-F 406

  Fly   419 MNLISDRGFKQPLYNTIHKNVCHTPNPVYLYSFNYQGPLSYASAYTSANVTGKYGVVHCDDLLYL 483
            ..::.|..|..|..........|.  ||:.|.|.::.  |:......::|...:|    |::|::
Mouse   407 KEMMKDFTFVIPALQVAQFQRSHA--PVFFYEFQHRP--SFFKDSKPSHVKADHG----DEILFI 463

  Fly   484 FRSPLLFPDFQRNSTEAKVIHS--FVDYFVHFAKFGKPRNSESLTPCSIEVLQSRPDGICDYHEF 546
            |||  .:...|.:.||.:.:.|  .:.|:.:||:...| |||.|                .|...
Mouse   464 FRS--FWGGTQVDFTEEEELLSRRMMKYWANFARQRNP-NSEGL----------------PYWPM 509

  Fly   547 ANAPDAYQGFEVH--VASEFQTDRVNLWSHILNEK 579
            .:..:.|...:..  |....:|.|:..|:..|.||
Mouse   510 FDQDEQYLQLDTQPAVGRALKTRRLQFWTKTLPEK 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhe	NP_523758.3	alpha/beta hydrolases	38..527	CDD:473884	153/499 (31%)
Ces2h	NP_001258974.1	COesterase	30..537	CDD:395084	158/546 (29%)