Protein Alignment Jhe and alpha-Est2

DIOPT Version :10

• Sequence 1: NP_523758.3
• Gene: Jhe / 36780
• FlyBaseID: FBgn0010052
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_524268.3
• Gene: alpha-Est2 / 40908
• FlyBaseID: FBgn0015570
• Length: 566
• Species: Drosophila melanogaster
• Alignment Length: 531
• Identity: 161/531 - (30%)
• Similarity: 254/531 - (47%)
• Gaps: 89/531 - (16%)

  Fly    50 YQSERFEAFMGIPYALPPIGDLRFSNPKVMPKLLGMYDASAPKMDCIQKNYLLPTPVVYGDEDCL 114
            |..|.:.||.|||||.||:|||||..|:......|:.:.:..:...:|:|.||  .:|.|.||||
  Fly    51 YDKEPYFAFEGIPYAKPPVGDLRFRAPQPPEPWQGVLNCTTNRSKPMQRNMLL--GIVEGSEDCL 113

  Fly   115 YLNVYRPEIR-KSALPVMVYIHGGGFFGGSAGPGVTGPEYFMDSGEVILVTMAYRLGPFGFLSTQ 178
            :||||...:: :..|||:|:|:||||..|.|...:..|:|||.. .|:.|.:.|||...||||.:
  Fly   114 HLNVYVKALKSEKPLPVIVWIYGGGFQKGEASRDIYSPDYFMKK-PVVFVAINYRLAALGFLSLK 177

  Fly   179 DAVMS--GNFGLKDQNLALRWVQRNIRFFGGDPQRVTIFGQSAGGVAAHMHLLSPRSHGLFHRVI 241
            |..:.  ||.|||||.:||||:.:||..|.|||..:|:.|:|||..:.|:.:.:.::.||||:.|
  Fly   178 DPKLDVPGNAGLKDQVMALRWISQNIAHFNGDPNNITLMGESAGSASVHVMMTTEQTRGLFHKAI 242

  Fly   242 SMSGTANVPFAIAEQPLEQARLLAEFADVPD-------ARNL------STVKLTKALRRINATKL 293
            ..||.|                |:|:.:.||       |:||      ....:...|.::.|.::
  Fly   243 MQSGCA----------------LSEWVESPDNNWAFRLAQNLGYKGDEKDADVLSFLSKVCARQI 291

  Fly   294 LNAGDGLKYWDVDHMTN-----FRPVVEEGLEVD-AFLNAHPMDMLAQGMPTSIPLLLGTVPGEG 352
              |.......::|.:.:     |.||:|. .|.| ..:.....|:|::.....||:::|....||
  Fly   292 --AAIDQDVINLDEVRSFLLFAFGPVIEP-YETDHCVVPKRHKDLLSEAWGNDIPVIVGGNSFEG 353

  Fly   353 --AVRVV-----------NILGNETLRQSFNLRFDELLQELLEFPASFSQDRREKMMDLLVEVYF 404
              :.::|           |||..| :|::.:|...:||...|:                  ::||
  Fly   354 LFSYQLVRKDPWALKNFHNILPRE-VRETSSLEGQDLLVRRLK------------------QLYF 399

  Fly   405 QGQHEVNELTVQGF--MNLISDRGFKQPLYNTIHKNVCHTP-NPVYLYSFNYQGPLSYASAYTSA 466
              .:|:.| :::.|  :|:.|.|......:..|.....:.| .|.|||.|::..|  :.:.:...
  Fly   400 --NNEMQE-SMEMFEALNIFSHRQIWHDTHRFILARQSYAPKTPTYLYRFDFDSP--HFNQFRRL 459

  Fly   467 NVTGK--YGVVHCDDLLYLFRSPLLFPDFQRNSTEAKVIHSFVDYFVHFAKFGKPRNSESLTPCS 529
             |.|.  .||.|.|:|.|||.: ::.....::|.|.|.|...|..:..||..|.| |...|....
  Fly   460 -VCGDRIRGVAHADELSYLFYN-IIASKLDKSSMEYKTIERMVGMWTSFASSGNP-NCPELGSAK 521

  Fly   530 IEVLQSRPDGI 540
            .|.:|.:.:.:
  Fly   522 WEAVQLKENAV 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhe	NP_523758.3	alpha/beta hydrolases	38..527	CDD:473884	159/516 (31%)
alpha-Est2	NP_524268.3	COesterase	34..556	CDD:395084	161/531 (30%)