Protein Alignment Jhe and ces2.3

DIOPT Version :10

• Sequence 1: NP_523758.3
• Gene: Jhe / 36780
• FlyBaseID: FBgn0010052
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_001265277.1
• Gene: ces2.3 / 394897
• XenbaseID: XB-GENE-29209066
• Length: 565
• Species: Xenopus tropicalis
• Alignment Length: 613
• Identity: 174/613 - (28%)
• Similarity: 278/613 - (45%)
• Gaps: 112/613 - (18%)

  Fly     6 MLQLLLLGQLLAGPGPFCAAL---ATVDQLTVCPPSVGCLKGTNLQGYQSERF-EAFMGIPYALP 66
            ::::|||         .|..|   .|.|...:.....|.|.|..:...:::|. ..|||:|:|.|
 Frog    12 LIKVLLL---------CCVTLEIYGTEDARPLLTTKYGQLLGNTVGAKETDRLVHVFMGVPFAKP 67

  Fly    67 PIGDLRFSNPKVMPKLLGMYDASAPKMDCIQ-------------KNYLLPTPVVYGDEDCLYLNV 118
            |||.|||..|:.:.....:.:|:|....|:|             ..:..| ||   .||||||||
 Frog    68 PIGLLRFEAPQPLEPWSSVREATAAPPMCLQDKRGMEDLAEFFKAKFDFP-PV---SEDCLYLNV 128

  Fly   119 YRPEIR--KSALPVMVYIHGGGFFGGSA----GPGVTGPEYFMDSGEVILVTMAYRLGPFGFLST 177
            :.|..|  ...|||||:|||||...|.|    |..:...|      .|::|::.||||..||.|:
 Frog   129 FTPADRGENPELPVMVFIHGGGLTMGGASMFEGTALCAYE------NVVVVSIQYRLGIMGFFSS 187

  Fly   178 QDAVMSGNFGLKDQNLALRWVQRNIRFFGGDPQRVTIFGQSAGGVAAHMHLLSPRSHGLFHRVIS 242
            .|..:.||||..||..||:||:.||:.|||:||.|||||:|||||:....:|||.|.||||:.|:
 Frog   188 GDKEVRGNFGFLDQVAALQWVRDNIKDFGGNPQSVTIFGESAGGVSVSAQVLSPLSKGLFHKAIA 252

  Fly   243 MSGTANVPFAIAEQPLEQARLLAEFADVPDARNLSTVKLTKALRRINATKLLNAGDGLKYWDVDH 307
            .||.|.:|..:..:..|...||:..|::   .:.|...|...|::....:::.....:::
 Frog   253 ESGVAILPGLMTSKNEEILPLLSVVANI---SSCSVSDLVGCLKKKTEDEIVAITAAMRF----- 309

  Fly   308 MTNFRPVVEEGLEVDAFLNAHPMDMLAQGMPTSIPLLLGTVPGE-GAV--RVVNILGNETLRQSF 369
             ..| |.|.:|:    ||.....::||......:|.|:|....| |.:  ..:||.|   .|:..
 Frog   310 -VMF-PAVVDGV----FLPKPAEEILAAKESNPVPFLIGINNHEFGWILPLALNITG---YREGM 365

  Fly   370 NLRFDELLQELLEFPASFSQDRREKMMDLLVEVYFQGQHEVNELTVQGFMNLISDRGFKQPLYNT 434
            ..:..:.:...|....:.|     .::..::|.||...::..||. ..|::|:.|..|..|...|
 Frog   366 EKKDIQAILGALPLLKTVS-----NVIPFIMEEYFGDTNDPKELR-NNFLDLVGDIIFVIPALRT 424

  Fly   435 --IHKNVCHTPNPVYLYSFNYQGPLSYASA---YTSANVTGKYGVVHCDDLLYLFRSPLLFPD-- 492
              .|::   :..|||.|.|.:: |..:|.:   :..|:        |.|:|.::...|.|...
 Frog   425 AKYHRD---SGLPVYFYEFQHR-PSMFADSKDDFVKAD--------HGDELYFVVGGPFLKSGIL 477

  Fly   493 FQRNSTEAKVIHS--FVDYFVHFAKFGKPRNSESLTPCSIEVLQSRPDGICDYHEFANAPDAYQG 555
            |:.|.||.:.|.|  .:.|:.:||:.|.|...                |:.::.::....|.
 Frog   478 FKSNGTEEEKILSKTIMKYWANFARNGDPNGL----------------GLAEWPKYDEDEDY--- 523

  Fly   556 FEVHV----ASEFQTDRVNLWSHILNEK 579
            .|:::    :...:..|:..|:..|.:|
 Frog   524 LEINLTQKSSQRLKGGRLKFWTITLPDK 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhe	NP_523758.3	alpha/beta hydrolases	38..527	CDD:473884	160/520 (31%)
ces2.3	NP_001265277.1	COesterase	33..544	CDD:395084	164/574 (29%)