Protein Alignment Jhe and Ces2e

DIOPT Version :10

• Sequence 1: NP_523758.3
• Gene: Jhe / 36780
• FlyBaseID: FBgn0010052
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_766347.1
• Gene: Ces2e / 234673
• MGIID: 2443170
• Length: 559
• Species: Mus musculus
• Alignment Length: 547
• Identity: 160/547 - (29%)
• Similarity: 237/547 - (43%)
• Gaps: 84/547 - (15%)

  Fly    58 FMGIPYALPPIGDLRFSNPKVMPKLLGMYDASAPKMDCIQKNYLLPT----------PVVYGDED 112
            |:|||:|.||:|.|||:.|:......|:.|.::....|:|.:.|:.:          |.:...||
Mouse    58 FLGIPFAKPPVGPLRFAPPEAPEPWSGVRDGTSHPNMCLQNDNLMGSEDLKMMNLILPPISMSED 122

  Fly   113 CLYLNVYRP--EIRKSALPVMVYIHGGGFFGGSA----GPGVTGPEYFMDSGEVILVTMAYRLGP 171
            |||||:|.|  ....|.|||||:||||....|.|    |..:...|      :|::|.:.||||.
Mouse   123 CLYLNIYVPAHAHEGSNLPVMVWIHGGALTVGMASMYDGSMLAATE------DVVVVAIQYRLGV 181

  Fly   172 FGFLSTQDAVMSGNFGLKDQNLALRWVQRNIRFFGGDPQRVTIFGQSAGGVAAHMHLLSPRSHGL 236
            .||.||.|....||:|..||..||||||:||..|||:|.||||||:||||.:...|::||.|.||
Mouse   182 LGFFSTGDQHAKGNWGYLDQVAALRWVQQNIVHFGGNPDRVTIFGESAGGTSVSSHVVSPMSQGL 246

  Fly   237 FHRVISMSGTANVPFAIAEQPLEQARLLAEFADVPDARNLSTVKLTKALRRINATKLLNAGDGLK 301
            ||..|..||.|.:|..|:.......|::|..:... |.|..|  |...||..|..::|
Mouse   247 FHGAIMESGVAVLPDLISSSSEMVHRIVANLSGCA-AVNSET--LMCCLRGKNEAEML------- 301

  Fly   302 YWDVDHMTNFRPVVEEGLEVDAFLNAHPMDMLAQGMPTSIPLLLGTVPGEGAVRVVNILGNETLR 366
              .::.:....|.|.:|    .||..||.:::|......:|.::|....|....:..|:....
Mouse   302 --AINKVFKIIPGVVDG----EFLPKHPQELMASKDFHPVPSIIGINNDEYGWILPTIMDPAQ-- 358

  Fly   367 QSFNLRFDELLQELLEFPASFSQDRREKMM-----DLLVEVYFQGQHEVNELTVQGFMNLISDRG 426
                 :.:|:.::.|  ||.......:.|:     |||:|.|.....:...|..| |..:..|..
Mouse   359 -----KIEEITRKTL--PAVLKSTALKMMLPPECGDLLMEEYMGDTEDPETLQAQ-FREMKGDFM 415

  Fly   427 FKQPLYNTIHKNVCHTPNPVYLYSFNYQGPL--SYASAYTSANVTGKYGVVHCDDLLYLFRSPLL 489
            |..|.....|....|.  |||.|.|.::...  .:...|..|:        |.|::..:|.....
Mouse   416 FVIPALQVAHFQRSHA--PVYFYEFQHRPSFFKDFRPPYVKAD--------HGDEIFLVFGYQFG 470

  Fly   490 FPDFQRNSTEAKVIHSFVDYFVHFAKFGKPRNSESLTPCSIEVLQSRPDGICDYHEFANAPDAYQ 554
            .........|.::....:.|:.:||:.|.| |||.|                .|....:..:.|.
Mouse   471 NIKLPYTEEEEQLSRRIMKYWANFARHGNP-NSEGL----------------PYWPVMDHDEQYL 518

  Fly   555 GFEVH--VASEFQTDRVNLWSHILNEK 579
            ..::.  |....:..|:..|:..|.:|
Mouse   519 QLDIQPSVGRALKARRLQFWTKTLPQK 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhe	NP_523758.3	alpha/beta hydrolases	38..527	CDD:473884	153/491 (31%)
Ces2e	NP_766347.1	COesterase	30..538	CDD:395084	157/538 (29%)