Protein Alignment Jhe and Ces2c

DIOPT Version :10

• Sequence 1: NP_523758.3
• Gene: Jhe / 36780
• FlyBaseID: FBgn0010052
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_663578.1
• Gene: Ces2c / 234671
• MGIID: 2385905
• Length: 561
• Species: Mus musculus
• Alignment Length: 551
• Identity: 168/551 - (30%)
• Similarity: 246/551 - (44%)
• Gaps: 92/551 - (16%)

  Fly    58 FMGIPYALPPIGDLRFSNPKVMPKLLGMYDASAPKMDCIQ-------------KNYLLPTPVVYG 109
            |:|||:|.||:|.|||:.|:......|:.|.:|....|:|             |..|...|:
Mouse    60 FLGIPFAKPPVGPLRFAPPEAPEPWSGVRDGTAHPAMCLQNLDMLNEAGLPDMKMMLSSFPM--- 121

  Fly   110 DEDCLYLNVYRP--EIRKSALPVMVYIHGGGFFGGSA----GPGVTGPEYFMDSGEVILVTMAYR 168
            .|||||||:|.|  ....|.|||||:||||....|.|    |..:|..|      ::::||:.||
Mouse   122 SEDCLYLNIYTPAHAHEGSNLPVMVWIHGGALVIGMASMFDGSLLTVNE------DLVVVTIQYR 180

  Fly   169 LGPFGFLSTQDAVMSGNFGLKDQNLALRWVQRNIRFFGGDPQRVTIFGQSAGGVAAHMHLLSPRS 233
            ||..||.||.|....||:|..||..||||||:||..|||:|.||||||:||||.:...|::||.|
Mouse   181 LGVLGFFSTGDQHARGNWGYLDQAAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSHVVSPMS 245

  Fly   234 HGLFHRVISMSGTANVPFAIAEQPLEQARLLAEFADVPDARNLSTVKLTKALRRINATKLLNAGD 298
            .||||..|..||.|.:|..|:|   ....:....|.:.....:.:..|.:.||..:..::|
Mouse   246 QGLFHGAIMESGVALLPDLISE---TSEMVSTTVAKLSGCEAMDSQALVRCLRGKSEAEIL---- 303

  Fly   299 GLKYWDVDHMTNFRPVVEEGLEVDAFLNAHPMDMLAQGMPTSIPLLLGTVPGEGAVRVVNILGNE 363
                 .::.:....|.|.:|    .|...||.::||......:|.::|....|....:..::|:.
Mouse   304 -----AINKVFKMIPAVVDG----EFFPRHPKELLASEDFHPVPSIIGVNNDEFGWSIPVVMGSA 359

  Fly   364 TLRQSFNLRFDELLQELLEFPASFSQDRREKMM------DLLVEVYFQGQHEVNELTVQGFMNLI 422
            .:.:...   .|.||.:|       :|...:||      |||:|.|.....:...|.:| |..::
Mouse   360 QMIKGIT---RENLQAVL-------KDTAVQMMLPPECSDLLMEEYMGDTEDAQTLQIQ-FTEMM 413

  Fly   423 SDRGFKQPLYNTIHKNVCHTPNPVYLYSFNYQGPLSYASAYTSANVTGKYGVVHCDDLLYLFRSP 487
            .|..|..|.....|....|.  |||.|.|  |.|.||.......:|...    |.|::.::|.|
Mouse   414 GDFMFVIPALQVAHFQRSHA--PVYFYEF--QHPPSYFKDVRPPHVKAD----HADEIPFVFAS- 469

  Fly   488 LLFPDFQRNSTEAKVIHS--FVDYFVHFAKFGKPRNSESLTPCSIEVLQSRPDGICDYHEFANAP 550
             .|...:.:.||.:.:.|  .:.|:.:||:.|.| |||.|                .|....:..
Mouse   470 -FFWGMKLDFTEEEELLSRRMMKYWANFARHGNP-NSEGL----------------PYWPVMDHD 516

  Fly   551 DAYQGFEVH--VASEFQTDRVNLWSHILNEK 579
            :.|...::.  |....:..|:..|:..|.:|
Mouse   517 EQYLQLDIQPAVGRALKAGRLQFWTKTLPQK 547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhe	NP_523758.3	alpha/beta hydrolases	38..527	CDD:473884	161/495 (33%)
Ces2c	NP_663578.1	COesterase	32..540	CDD:395084	165/542 (30%)
		Prevents secretion from ER. /evidence=ECO:0000255	558..561