Protein Alignment Jhe and cest-7

DIOPT Version :10

• Sequence 1: NP_523758.3
• Gene: Jhe / 36780
• FlyBaseID: FBgn0010052
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_001257187.1
• Gene: cest-7 / 182819
• WormBaseID: WBGene00007693
• Length: 606
• Species: Caenorhabditis elegans
• Alignment Length: 571
• Identity: 141/571 - (24%)
• Similarity: 232/571 - (40%)
• Gaps: 110/571 - (19%)

  Fly    24 AALA-TVDQLTVCPPSVGCLKG-TNLQGYQSERFEAFMGIPYALPPIGDLRFSNPKVMPKLLGMY 86
            |.|| :|....|...:.|.::| |:....::.:: .|.|||:|.||:|.|||:.|:......|:.
 Worm    28 ALLALSVKSFKVLNTNYGKVRGITDFSDKRNHKY-IFKGIPFAKPPLGLLRFALPEEPNTWNGVL 91

  Fly    87 DASAPKMDCIQKNYLLPTPVVYGDEDCLYLNVYRPE-IRKSALPVMVYIHGGGFFGGSAG--PGV 148
            |.|.....|:..:.|.........|||||:|::..| ......||:||.|||.|...||.  |..
 Worm    92 DGSKYSAACLSNSSLASAQQENISEDCLYINIFTSEYCLAHKCPVLVYYHGGSFNLDSATMFPDK 156

  Fly   149 TGPEYFMDSGEVILVTMAYRLGPFG-FLSTQDAVMSGNFGLKDQNLALRWVQRNIRFFGGDPQRV 212
            ...|.::||| ::....|||||.|| |...:..::..|..:.|...:|.:|..||..|||||..|
 Worm   157 FILERYVDSG-IVFAIPAYRLGVFGQFYLGEQGIVPANLLIHDCIRSLNFVHDNIASFGGDPNYV 220

  Fly   213 TIFGQSAGG----VAAHMHLLSPRSHGLFHRVISMSGTANVPFAIAEQPLEQARL--LAEFADVP 271
            |:.|.|:||    .....:.:.|... ||.:.|.:|       :|.....|..::  ..|.|...
 Worm   221 TLMGHSSGGQLVNAMGFSNQIDPEKK-LFQQFIVLS-------SIGMYGFEDLQIGNSYEIARRH 277

  Fly   272 DARNLSTVKLTKALRRINATKLLNAGDGLKYWDVDHMTNFRPVVEEG--LEVDAFLNAHPMDMLA 334
            :..:.::.::...:|.|:|.:||.....:.  ||| :..|:.::...  ::|...|:....::.|
 Worm   278 NCTSENSQEIVDCMRNIDALQLLQTQTVMD--DVD-LLFFKAIIRAPPLMDVKQKLSEFKENVTA 339

  Fly   335 QGMPTSIPLLLGTVPGEGAVRVVNILGNETLRQSFNLRFDE---LLQELLEFPASFSQDRREKMM 396
            :.|      |.|....|..:                .::.:   :....|:|         |..:
 Worm   340 RNM------LCGVTDNEFTI----------------FKYPDGYYISATFLDF---------ENPV 373

  Fly   397 DLLVEVYFQGQHEVNELTVQGFMNLISDRGFKQPLYNTIHKNVCHTPNPVYLYSFNYQGPLSYAS 461
            | .|.||   :::...:| ..|:|..|...|....  |..:.:.:....|||:. :.|.|.|
 Worm   374 D-TVNVY---RNKFTNIT-PTFVNSDSSAVFVSAA--TYSEALTNAGGNVYLFE-SRQKPFS--- 427

  Fly   462 AYTSANVTGKYGVVHCDDLLY---LFRSPLLFPDFQRNSTEAKVIHSFVD-YFVHFAKFGKPR-N 521
                         :|..|:.|   :.|.       :.::|:..::.||.. ..|:|.|||.|. |
 Worm   428 -------------MHVTDMQYFIGIHRE-------KNHTTDMDILDSFYSKLLVNFTKFGSPSPN 472

  Fly   522 SESLTPCSIEVLQSRPDGICDYHEFANAPDAYQGFEVHVASEFQTDRVNLW 572
            .|...|..:..:             |...|..||.|..:.:.|..:.||.|
 Worm   473 WEKYDPSKMNFM-------------AMEIDTEQGIEPKMENGFHEELVNFW 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhe	NP_523758.3	alpha/beta hydrolases	38..527	CDD:473884	126/509 (25%)
cest-7	NP_001257187.1	alpha/beta hydrolases	38..510	CDD:473884	136/559 (24%)