Protein Alignment Jhe and cest-19

DIOPT Version :10

• Sequence 1: NP_523758.3
• Gene: Jhe / 36780
• FlyBaseID: FBgn0010052
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_509187.4
• Gene: cest-19 / 180973
• WormBaseID: WBGene00020125
• Length: 607
• Species: Caenorhabditis elegans
• Alignment Length: 521
• Identity: 148/521 - (28%)
• Similarity: 229/521 - (43%)
• Gaps: 92/521 - (17%)

  Fly    40 GCLKGTNLQGYQSERFEAFMGIPYALPPIGDLRFSNPKVMPKLLGMYDASAPKMDCIQ------- 97
            |.::|..|. ...:.:..|.|||:|:||:|.|||..||...|..|:.:|:.....|:|
 Worm    33 GAIRGERLL-TDGQDYSVFKGIPFAMPPVGYLRFQMPKEPAKWRGVMNATQYSAMCMQNIDENDA 96

  Fly    98 ---KNYLLPTPVVYGDEDCLYLNVYRP---EIRKSALPVMVYIHGGGFFGGSAGPGVTGPEYFMD 156
               :.|     |.:..||||||||:.|   :......||:|:||||.|   ..|.|...|:..:.
 Worm    97 GEPERY-----VAHVSEDCLYLNVFSPTPYQYTNDTYPVIVFIHGGRF---QTGSGSDIPQRAIL 153

  Fly   157 SG----EVILVTMAYRLGPFGFLSTQDAVMSGNFGLKDQNLALRWVQRNIRFFGGDPQRVTIFGQ 217
            |.    :::.||..|||||.||.||.|:|:.||.||.||..||:||:.|...|||||..:.:.|.
 Worm   154 SNFVSRKIVFVTFNYRLGPLGFASTGDSVLPGNIGLWDQIWALKWVKANAEVFGGDPSNILLMGH 218

  Fly   218 SAGGVAAHMHLLSPRSHGLFHRVISMSGTANVPFAIAEQPLEQARLLAEFADVPDARNLSTVKLT 282
            ..|..:|.:..||||:.|||.:|:.|||:|..|..:..   .|........|....|..::.:|.
 Worm   219 GTGAASASLLALSPRAEGLFQKVLLMSGSALQPGVVRN---TQVNATWNMNDRFGCRAFNSSELL 280

  Fly   283 KALRRINATKLLNAGDGLKYWDVDHMTNFRPVVEEGLEVDAFLNAHPMDMLAQGMPTSIPLLLGT 347
            ...|:.:..::..    .|....|....|.|:::   .|...|...|..:......|  |:::||
 Worm   281 DCARKRSKEEIFQ----YKRLHFDDYEEFVPIID---GVGGILPEPPEQLTLHRRKT--PIVIGT 336

  Fly   348 VPGEGAVRVVNILGNETLRQSFNLRFDELLQELLEFPASFSQDRREKMMDLLVEVYFQGQHEVNE 412
            ...|.::|:  :|.||.     :|.|           :|.:.:..|.:.|.|...:.|.|:  :.
 Worm   337 TKDESSLRI--LLLNEK-----DLNF-----------SSITWENGETLADNLTLGFKQFQN--HR 381

  Fly   413 LTVQG----FMNLISDRGFKQP-LYNTIHKNVCH----TPN------------PVYLYSFNYQGP 456
            |..||    ::....|..|.:. |:|::.|...|    .|.            |||||||:
 Worm   382 LISQGCKSEYVWTQVDPSFPESVLFNSLLKMYSHFWYDAPASQLATYYLKHDLPVYLYSFD---- 442

  Fly   457 LSYASAYTSANVTGKYGVVHCDDLLYLFRSPLLFPDFQRN---STEAKVIHSFVDYFVHFAKFGK 518
                  :.|.|........|..|.|::|.....|.:.:::   ..:.:|:..|.:...:||.:|.
 Worm   443 ------HISENFYDIDRAFHGVDKLHIFNVTPRFLNKRKDMNWQLDQRVVEIFSELVANFALYGT 501

  Fly   519 P 519
            |
 Worm   502 P 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhe	NP_523758.3	alpha/beta hydrolases	38..527	CDD:473884	148/521 (28%)
cest-19	NP_509187.4	alpha/beta hydrolases	24..544	CDD:473884	148/521 (28%)