Protein Alignment Jhe and glit-1

DIOPT Version :10

• Sequence 1: NP_523758.3
• Gene: Jhe / 36780
• FlyBaseID: FBgn0010052
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_508807.1
• Gene: glit-1 / 180747
• WormBaseID: WBGene00018878
• Length: 730
• Species: Caenorhabditis elegans
• Alignment Length: 527
• Identity: 148/527 - (28%)
• Similarity: 216/527 - (40%)
• Gaps: 137/527 - (25%)

  Fly    58 FMGIPYALPPIGDLRFSNPKVM-------PKLLGMYDASAPKMDCIQKNYLLPTPVV------YG 109
            |:|:|||.||....||..|:.:       |.|...|.||     |.|.....|:|.|      ..
 Worm   109 FLGVPYAEPPTSQRRFKPPQQLTVFPGKQPYLAFNYAAS-----CAQDVEKSPSPFVDHPYPFMV 168

  Fly   110 DEDCLYLNVYRPEIRKSA---LPVMVYIHGGGFFGGSAGPGVTGPEYFMDSGEVILVTMAYRLGP 171
            ||||||||::.|:|.|:|   .||:|:.|||.|..|||.   ..|.:.:.|..:::||:.||||.
 Worm   169 DEDCLYLNIFSPDISKNAQTTYPVIVFFHGGNFQTGSAN---EWPAHGLASRGMVVVTVNYRLGA 230

  Fly   172 FGFLSTQDAVMSGNFGLKDQNLALRWVQRNIRFFGGDPQRVTIFGQSAGGVAAHMHLLSPRSHGL 236
            |||:|..|: .:||:||:||.|||.:|:.||..||||||.||:.|..||..:...|:.||.|..|
 Worm   231 FGFMSMGDS-ETGNYGLQDQRLALEFVKNNIVTFGGDPQAVTVVGHDAGAASIGFHMQSPYSRHL 294

  Fly   237 FHRVISMSGTANVPF-------AIA-------------EQPLEQAR----LLAEFADVPDARNLS 277
            |....:||| |.|.:       |:|             .|.:.|.|    |.....|:.||....
 Worm   295 FRSAATMSG-AEVSYHSYIGKTALAFNNTMKLGRYAGCTQAVAQHRWDCILTRSTGDIIDATRNI 358

  Fly   278 TVKLTKALRRINATKLLNAGDGLKYWDVDHMTNFRPVVEEGLEVDAFLNAHPMDML--AQGMPTS 340
            .::..:.|                         |.|.|:     ..:|..:|:..|  |....||
 Worm   359 PIEYNRYL-------------------------FMPTVD-----GKYLPGNPLWTLVNAPSGETS 393

  Fly   341 I----PLLLGTVPGEGAVRVVNILGNETLRQSFNLRFDELLQELLEFPASFSQD---------RR 392
            |    |:|:|....:|:..|:     |..|.....:|:::..|.|:   |:|.:         .|
 Worm   394 IMSPVPMLIGMNAQDGSEVVL-----EDRRLGEFSQFNDVDHEYLK---SYSLEYCYRHNYSMNR 450

  Fly   393 EKMMDLLVEVY-FQGQHEVNELTVQGFMNLISDRGFKQPLYNTIHKNVCHTPNPVYLYSFNYQGP 456
            |...|.::..| |...........:.|:...:|..:..|:..:.|           |:|.:....
 Worm   451 EATADAILSKYTFWPDRAAAWAIKENFIQFATDAYYTAPMQLSSH-----------LHSSSGSRV 504

  Fly   457 LSYASAYTSAN-------VTGKYGVVHCDDLLYLFRSPLL-------------FPDFQRNS--TE 499
            ..|.:.|..:.       :....||....||..:|..|.|             |.|..||:  |.
 Worm   505 FQYVNNYNFSRQHPNLLFIPDWMGVCRDCDLYLMFGYPFLPDELRPIGLRGINFTDTDRNASRTF 569

  Fly   500 AKVIHSF 506
            :.:|..|
 Worm   570 SNIIRRF 576

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhe	NP_523758.3	alpha/beta hydrolases	38..527	CDD:473884	148/527 (28%)
glit-1	NP_508807.1	alpha/beta hydrolases	98..629	CDD:473884	148/527 (28%)