Protein Alignment Jhe and ace-4

DIOPT Version :10

• Sequence 1: NP_523758.3
• Gene: Jhe / 36780
• FlyBaseID: FBgn0010052
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_496962.1
• Gene: ace-4 / 175074
• WormBaseID: WBGene00000038
• Length: 602
• Species: Caenorhabditis elegans
• Alignment Length: 558
• Identity: 158/558 - (28%)
• Similarity: 238/558 - (42%)
• Gaps: 112/558 - (20%)

  Fly    29 VDQLTVCPPSV-----GCLKGTNLQGYQSERFEAFMGIPYALPPIGDLRFSNPKVMPKLLGMYDA 88
            :|.:....|.|     |.:|||.. .:.|::...|.|:|:|.|.:.|.||..|:...:..|:|||
 Worm    18 IDSVQAVHPVVLETKLGDIKGTEF-FFLSKKIRTFFGVPFAEPAVEDFRFRKPREKKQWRGLYDA 81

  Fly    89 SAPKMDCIQ--KNYLLPTPVVYG----------DEDCLYLNVYRPEIRKSALPVMVYIHGGGFFG 141
            :.|...|.|  .||   ....:|          .|||||||::.|....: |.|||:..||||:.
 Worm    82 TKPANACFQTRDNY---NTSFWGSEMWNANTQISEDCLYLNIWAPADAYN-LTVMVWFFGGGFYS 142

  Fly   142 GSAGPGVTGPEYFMDSGEVILVTMAYRLGPFGFLSTQDAVMSGNFGLKDQNLALRWVQRNIRFFG 206
            ||....:...:....:..||:|.:.|||||||||........||.||.||.|||.||::||..||
 Worm   143 GSPSLSIYDGKALTSTQNVIVVNINYRLGPFGFLYLGHPDAPGNMGLLDQQLALHWVRQNIVSFG 207

  Fly   207 GDPQRVTIFGQSAGGVAAHMHLLSPRSHGLFHRVISMSGT------ANVPFAIAEQPLEQARLLA 265
            |:|.:|.:||||||..:...||::|.|.|||...|..||:      .|.||. |:|..|:   |.
 Worm   208 GNPDKVAVFGQSAGAASIVAHLIAPGSRGLFKNAILQSGSLENTWAINSPFR-AKQKSEK---LL 268

  Fly   266 EFADVPDARNLSTVKLTKALRRINATKLLNAGDGLKYWDVDHMTNFR---PVVEEGLEVDAFLNA 327
            |....    |.:||..:.|..|:.:.:.|:    |..|::. :|...   .:|.........|:|
 Worm   269 ELVGC----NKTTVDTSMACLRLVSPEQLS----LSTWNIS-LTYLEFPFVIVSRDKHFFGHLDA 324

  Fly   328 HPMDMLAQG-MPTSIPLLLGTVPGEGAVRVVNILGNETLRQSFN---------LRFDELLQELLE 382
            |.  .|.:| ....:.|::|....||     |......|.|.|:         ..||.|:.....
 Worm   325 HA--ALREGDFNRDVNLMIGMNKDEG-----NYWNIYQLPQFFDKADPPELNRTEFDFLIDRTFS 382

  Fly   383 F---------------PASFSQDRREKMMDLLVEVYFQGQHEVNELTVQGFMNL----ISDRGFK 428
            .               |......|:.:        ::.||  :|::....|.:.    ::|:...
 Worm   383 IQPDIIRSAAKYIYSDPNCTDHGRKTR--------FYAGQ--MNQIVGDYFFSCDSLWLADQFRS 437

  Fly   429 QPLYNTIHKNVCHTPNPVYLYSFNYQGPLSYASAYTSANVTGKY-GVVHCDDLLYLFRSPLLFPD 492
            .|...:  .:....|..|::|.|...         :|||...|: |.:|..::.|:|..||   .
 Worm   438 IPRVKS--SSPQRKPGKVFVYHFTQS---------SSANPWPKWTGAMHGYEIEYVFGIPL---S 488

  Fly   493 FQRNSTEAKVIHS--FVDYFVHFAKFGKP-----RNSE 523
            :.:|....:.|.|  .:.::..|||.|.|     :|||
 Worm   489 YSKNYKRREQIFSRKIMQFWASFAKNGTPKLRVLKNSE 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhe	NP_523758.3	alpha/beta hydrolases	38..527	CDD:473884	156/549 (28%)
ace-4	NP_496962.1	COesterase	28..562	CDD:395084	156/548 (28%)