Protein Alignment Jhe and LOC1273105

DIOPT Version :10

• Sequence 1: NP_523758.3
• Gene: Jhe / 36780
• FlyBaseID: FBgn0010052
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: XP_312052.3
• Gene: LOC1273105 / 1273105
• VectorBaseID: AGAMI1_000342
• Length: 554
• Species: Anopheles gambiae
• Alignment Length: 575
• Identity: 186/575 - (32%)
• Similarity: 259/575 - (45%)
• Gaps: 97/575 - (16%)

  Fly     4 QRMLQLLLLGQLLAGPGPFCAALATVDQLTVCPPSVGCLKGTNLQGYQSE-----RFEAFMGIPY 63
            ||...||||            |||:....:...|.:|...| .:||...:     .:.:|.||||
Mosquito     4 QRAPWLLLL------------ALASARGQSADRPIIGTSSG-QVQGTTEDCGLFCTYYSFKGIPY 55

  Fly    64 ALPPIGDLRFSNPKVMPKLLGMYDASAPKMDCIQKNYLLPTP--VVYGDEDCLYLNVYRPEIRKS 126
            |.||:|.|||::|.......|:.|||.....|       |||  :....|||||||||.|.: ..
Mosquito    56 AEPPVGALRFADPVPRAAWTGVRDASQHGSSC-------PTPDALPAEAEDCLYLNVYSPSL-VG 112

  Fly   127 ALPVMVYIHGGGFFGGSAGPGVTGPEYFMDSGEVILVTMAYRLGPFGFLSTQDAVMSGNFGLKDQ 191
            ..||||::|||.:.|||....:.|..|||.. .|::||:.||||..|||.|.|...|||:.:||.
Mosquito   113 TRPVMVFVHGGAYVGGSGDDALYGARYFMPE-NVVIVTLNYRLGVLGFLGTGDRSASGNWAIKDC 176

  Fly   192 NLALRWVQRNIRFFGGDPQRVTIFGQSAGGVAAHMHLLSPRSHGLFHRVISMSGTANVPFAIAEQ 256
            ..|||||||||..||||..|||||||||||...|...|||.:.|||.|.|:.||:|...:::...
Mosquito   177 VEALRWVQRNIGAFGGDAGRVTIFGQSAGGALVHFLTLSPLAVGLFERAITHSGSAINSWSLQPN 241

  Fly   257 PLEQARLLAEFADVPDARNLSTVKLTKALRRINATKLLNAGDGLKYWDVDHMT--------NFRP 313
            |.:||..:|....:   ....|..|..|||::....|::.         |..|        .|.|
Mosquito   242 PRQQAEKIAAELGI---HTTDTATLVSALRQVPYRDLISP---------DQTTLDELMVPLAFGP 294

  Fly   314 VVEEG-LEVDAFLNAHPMDMLAQGMPTSIPLLLGTVPGEGAV-RVVNILGNETLRQSFNLRFDEL 376
            |||.. ......|:..|::::..|...::||:.|....:..: ..|.::.|..:..:||.....|
Mosquito   295 VVEPADTPGQVALDRLPIELIESGSYRAVPLMAGFTDMDALLFSAVEMVTNPGIFDTFNNNPHLL 359

  Fly   377 LQELLEFPA------SFSQDRREKMMDLLVEVYFQGQHEVNELTVQGFMNLISDRGFKQPLYNTI 435
            :..:...||      :.||..|        :.|:|.|.....|..| |...::|..|..|.....
Mosquito   360 VPFVWNIPAGSAASSAVSQAFR--------QYYWQSQPLSPALLAQ-FSVYLTDLQFAYPQLEMA 415

  Fly   436 HKNVCHTPNPVYLYSFNYQGPLSYASAYTSANVTGKYGVVHCDDLLYLFRS--------PLLFPD 492
            .::.  :.:.||||.|.|.|.|:....:....:.   |.:|.|||.|||.:        |:
Mosquito   416 KRHA--SRSSVYLYQFKYDGDLNLVKQFAGIPLP---GAIHGDDLCYLFETKQFGGGELPI---- 471

  Fly   493 FQRNSTEAKVIHSFVDYFVHFAKFGKPRNSESLTPCSIEVLQS---RP--DGICD 542
               .|..|.|....:..:.:||:.|.|      ||.:..:||.   ||  .|:.|
Mosquito   472 ---TSHAATVRQRMLRLWTNFARDGNP------TPTADALLQGTLWRPLSPGMID 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhe	NP_523758.3	alpha/beta hydrolases	38..527	CDD:473884	168/519 (32%)
LOC1273105	XP_312052.3	COesterase	25..540	CDD:395084	177/542 (33%)