Protein Alignment Jhe and Ache

DIOPT Version :10

• Sequence 1: NP_523758.3
• Gene: Jhe / 36780
• FlyBaseID: FBgn0010052
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: XP_036020624.1
• Gene: Ache / 11423
• MGIID: 87876
• Length: 616
• Species: Mus musculus
• Alignment Length: 538
• Identity: 161/538 - (29%)
• Similarity: 233/538 - (43%)
• Gaps: 107/538 - (19%)

  Fly    42 LKGTNLQGYQSER----FEAFMGIPYALPPIGDLRFSNPKVMPKLLGMYDASAPKMDCIQ-KNYL 101
            ::|..|:|.:.:.    ..||:|||:|.||:|..||..|:......|:.||:..:..|.| .:.|
Mouse    43 VRGGQLRGIRLKAPGGPVSAFLGIPFAEPPVGSRRFMPPEPKRPWSGVLDATTFQNVCYQYVDTL 107

  Fly   102 LP--------TPVVYGDEDCLYLNVYRPEIR-KSALPVMVYIHGGGFFGGSAGPGVTGPEYFMDS 157
            .|        .|.....||||||||:.|..| .|..||:::|:||||:.|:|...|....:....
Mouse   108 YPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPASPTPVLIWIYGGGFYSGAASLDVYDGRFLAQV 172

  Fly   158 GEVILVTMAYRLGPFGFLS---TQDAVMSGNFGLKDQNLALRWVQRNIRFFGGDPQRVTIFGQSA 219
            ...:||:|.||:|.||||:   :::|  .||.||.||.|||:|||.||..|||||..||:||:||
Mouse   173 EGAVLVSMNYRVGTFGFLALPGSREA--PGNVGLLDQRLALQWVQENIAAFGGDPMSVTLFGESA 235

  Fly   220 GGVAAHMHLLSPRSHGLFHRVISMSGTANVPFAI--AEQPLEQARLLAEFADV-PDARNLSTVKL 281
            |..:..||:||..|..||||.:..|||.|.|:|.  |.:...:|.|||..... |.....:..:|
Mouse   236 GAASVGMHILSLPSRSLFHRAVLQSGTPNGPWATVSAGEARRRATLLARLVGCPPGGAGGNDTEL 300

  Fly   282 TKALRRINATKLLNAGDGLKYWDVDH-----------MTNFRPVVEEGLEVDAFLNAHPMDMLAQ 335
            ...||...|..|           |||           ..:|.|||:     ..||:..|..::..
Mouse   301 IACLRTRPAQDL-----------VDHEWHVLPQESIFRFSFVPVVD-----GDFLSDTPEALINT 349

  Fly   336 GMPTSIPLLLGTVPGEGAVRVV-NILGNETLRQSFNLRFDELLQELLEFPASFSQDRREKMMDLL 399
            |....:.:|:|.|..||:..:| .:.|.....:|...|...|....:..|         :..||.
Mouse   350 GDFQDLQVLVGVVKDEGSYFLVYGVPGFSKDNESLISRAQFLAGVRIGVP---------QASDLA 405

  Fly   400 VEV----YFQGQHEVNELTVQGFMN-LISDRGFKQPLYNTIHKNVCHTPN----------PVYLY 449
            .|.    |....|..:...::..|: ::.|           |..||....          .||.|
Mouse   406 AEAVVLHYTDWLHPEDPTHLRDAMSAVVGD-----------HNVVCPVAQLAGRLAAQGARVYAY 459

  Fly   450 SFNYQG-----PLSYASAYTSANVTGKYGVVHCDDLLYLFRSPLLFPDFQRNSTEAKVIHSFVDY 509
            .|.::.     ||             ..||.|..::.::|..| |.|.....:.|.......:.|
Mouse   460 IFEHRASTLTWPL-------------WMGVPHGYEIEFIFGLP-LDPSLNYTTEERIFAQRLMKY 510

  Fly   510 FVHFAKFG---KPRNSES 524
            :.:||:.|   .||:|:|
Mouse   511 WTNFARTGDPNDPRDSKS 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhe	NP_523758.3	alpha/beta hydrolases	38..527	CDD:473884	161/538 (30%)
Ache	XP_036020624.1	COesterase	37..563	CDD:395084	161/538 (30%)