Protein Alignment Jhe and nlgn4x

DIOPT Version :10

• Sequence 1: NP_523758.3
• Gene: Jhe / 36780
• FlyBaseID: FBgn0010052
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: XP_017946613.1
• Gene: nlgn4x / 100329189
• XenbaseID: XB-GENE-6036018
• Length: 833
• Species: Xenopus tropicalis
• Alignment Length: 635
• Identity: 177/635 - (27%)
• Similarity: 269/635 - (42%)
• Gaps: 122/635 - (19%)

  Fly    24 AALAT----VD---QLTVCPPSVGCLKGT------NLQGYQSERFEAFMGIPYALPPIGDLRFSN 75
            ||||.    ||   |..:.|.:.|.::||      .:.|    ..|.::|:|||.||.|:.||..
 Frog    30 AALAVRFTIVDCQAQHPIVPTNYGKIRGTRTPLPIEILG----PVEQYLGVPYASPPTGERRFQP 90

  Fly    76 PKVMPKLLGMYDASAPKMDCIQ-------KNYLLP--------TPVVY---GDEDCLYLNVYRP- 121
            |:......|:.:|:.....|.|       .|.:||        |.|.|   .:|||||||:|.|
 Frog    91 PEPPSSWTGIKNATQFAPVCPQFLDERSLLNDMLPIWFTANLDTVVSYVQDQNEDCLYLNIYVPT 155

  Fly   122 ----EIRKSA--------------------LPVMVYIHGGGFFGGSAGPGVTGPEYFMDSGEVIL 162
                ..:|.|                    .|||||||||.:..|: |..:.| ......|.||:
 Frog   156 EDGATTKKQADDIANNDRGEDEDIHDPNNKKPVMVYIHGGSYMEGT-GNMIDG-SILASHGNVIV 218

  Fly   163 VTMAYRLGPFGFLSTQDAVMSGNFGLKDQNLALRWVQRNIRFFGGDPQRVTIFGQSAGGVAAHMH 227
            :|:.||||..|||||.|....||:||.||..||||::.||..|||||:||||||..||.....:.
 Frog   219 ITVNYRLGVLGFLSTGDQAAKGNYGLLDQIQALRWIEENIGAFGGDPKRVTIFGSGAGASCVSLL 283

  Fly   228 LLSPRSHGLFHRVISMSGTANVPFAIAEQPLEQARLLAEFADVPDARNLSTVKLTKALRRINATK 292
            .||..|.|||.:.|..||||...:|:..||.:..|:|   ||......|.|:.|.:.||..|..:
 Frog   284 TLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRIL---ADKVGCDMLDTIDLVECLRDKNYKE 345

  Fly   293 LLNAGDGLKYWDVDHMTNFRPVVEEGLEVDAFLNAHPMDMLAQGMPTSIPLLLGTVPGEGAVRVV 357
            |:..    ......:...|.||::..:..|     .|..::.||...:..::||...|||...|.
 Frog   346 LIQQ----SITPATYHIAFGPVIDGDVIPD-----DPQILMEQGEFLNYDIMLGVNQGEGLKFVD 401

  Fly   358 NILGNE--TLRQSFNLRFDELLQELLEFPASFSQDRREKMMDLLVEVYFQGQHEVN-ELTVQGFM 419
            .::.||  .....|:......:..|..:|     :.::.:.:.:..:|.....:.| |...:..:
 Frog   402 GMVDNEDGVSLSDFDFSVSNFVDNLYGYP-----EGKDTLRETIKFMYTDWADKENPETRRKTLV 461

  Fly   420 NLISDRGFKQPLYNT--IHKNVCHTPNPVYLYSFNYQGPLSYASAYTSANVTGKYGVVHCDDLLY 482
            .|.:|..:..|...|  :|   ....:|.|.|:|.:.........:..:        .|.|::.|
 Frog   462 ALFTDHQWVAPAVATADLH---ARYGSPTYFYAFYHHCQSEMKPTWADS--------AHGDEVPY 515

  Fly   483 LFRSPLLFP------DFQRNSTEAKVIHSFVDYFVHFAKFGKPRNSESLTPCSIEVLQSRPDGIC 541
            :|..|::.|      :|.:|......:  .:.|:.:|||.|.|...   .|...:.:.::|:
 Frog   516 VFGIPMIGPTELFNCNFSKNDVMLSAV--VMTYWTNFAKTGDPNKP---VPQDTKFIHTKPN--- 572

  Fly   542 DYHEFA----NAPD---AYQGFEVHVASEFQTDRVNLW------SHILNE 578
            .:.|.|    :..|   .:.|.:..|...::..:|..|      .|.|||
 Frog   573 RFEEVAWSKYDPKDQLYLHIGLKPRVRDHYRATKVAFWLELVPHLHNLNE 622

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jhe	NP_523758.3	alpha/beta hydrolases	38..527	CDD:473884	156/548 (28%)
nlgn4x	XP_017946613.1	COesterase	46..610	CDD:395084	165/605 (27%)