Protein Alignment CG8414 and Nol9

DIOPT Version :9

• Sequence 1: NP_611084.2
• Gene: CG8414 / 36774
• FlyBaseID: FBgn0034073
• Length: 995
• Species: Drosophila melanogaster
• Sequence 2: NP_001365785.1
• Gene: Nol9 / 74035
• MGIID: 1921285
• Length: 715
• Species: Mus musculus
• Alignment Length: 586
• Identity: 130/586 - (22%)
• Similarity: 244/586 - (41%)
• Gaps: 131/586 - (22%)

  Fly   468 LKSNHVLAVIK--EDLEVYGTLVLTLLCGQISVNGYRARR----QEAITIYSPKGL--NWVSIS- 523
            |.|..||.::.  |.....|...:|.:.||:.|.|:...:    |:..::|:...|  |.|..:
Mouse   138 LGSGRVLMMLPPGEGFTFSGICRVTCVYGQLEVYGHIINQGQPPQDVFSVYTHSYLTINGVPYAE 202

  Fly   524 PTKTKKPVKDEV-------------NW--------------EELNKNFTRAQLDRIKTSFQRQTN 561
            |.|::|.::.|:             ||              |.:...|    :|.:||   .:.:
Mouse   203 PEKSEKAIRREIRALLKPYTKLDDRNWVVRYFPPLGSIMILERMQSRF----VDFLKT---YKCS 260

  Fly   562 AIVLLHRNTSAQQLVDTFGKHMAQNVFPLVNS---SNRPFG---QSETLLHCLIQSSDQSRTLQV 620
            :.|||..|...:                 |||   :.:..|   |......||    .:|....:
Mouse   261 SYVLLQENAPVR-----------------VNSEFTTLKKIGIRRQKRKKAICL----SESGLCAL 304

  Fly   621 PQVWNKLQMHATSRIIVAGGKGVGKSSLLRYLINRNLGQFPSMLLIDLDIGQPEIFVPQTISCTV 685
            .::.:...:.....|::.|...:|||:..|.|||:.|...|.:..::.|:||.|...|..::...
Mouse   305 EELVSVSCVDGCPVILLCGACDIGKSTFNRILINQLLNSIPGVDYLECDLGQTEFTPPGCVALLT 369

  Fly   686 IDEPLLGPGFLYNRQPEHAIVVGHTNIVLCAEQYARAVIQLVQNIQNDAKYSNIPWLINTMGYNK 750
            |.||||||.:.:.|:|:..:..|..|   |...|.. .|.:|:.:..|.| ...|.:|||||:..
Mouse   370 ITEPLLGPPYTHQRKPQRMVYYGKMN---CYNDYEN-YIDIVKYVFRDYK-REFPLIINTMGWVS 429

  Fly   751 GFGIELMALLVDRIRPTDLVQIAS------PIPINNF----DSVLDRNSLSQIK---------PI 796
            ..|:.|:..|:..:.|..:||:.|      |...:.:    |.:..::.:.:.:         .:
Mouse   430 DNGLRLLVDLIRVLSPNYVVQLYSDRCKFTPTLTSEYVELTDGLYTKSKIKRYRGFEIPEFGDNL 494

  Fly   797 IYSAEEFKINEIPKYTLHKL-------ISAVPAREKGTWSLSAKDMRYSNLLARLSSCLTGNAKS 854
            .::.||.:.:.:|.:|.|.|       :|:...:.:..::...:|:.....|::|...:..:...
Mouse   495 EFTYEEKESSPLPVFTGHVLLSVHSEFLSSKNEKNRAKYNRIFRDLAVLGYLSQLMLPVPESLSP 559

  Fly   855 LTDCQPLGV--SLESLKILH----PTSKNYSREELIRGMEANVVYLCH-------HGAG------ 900
            |....|..|  |..::::||    ||       .::..:.|:.|.||.       :..|
Mouse   560 LHSLTPYQVPFSAVAIRVLHADVAPT-------HILYAVNASWVGLCRIVDDMKGYTRGPILLAQ 617

  Fly   901 --LPQCLGIGVVRAIDYERKELYLVPAMPLQKMSLVDCLILGGEQSLPQGFLRDQGQGVSSSVPF 963
              :..|||.|:.|.||.:::..:::..:|.:::..|:||:: |..|:|....::| .|...|||:
Mouse   618 NPICDCLGFGICRGIDMDKRTYHILTPLPPEELKTVNCLLV-GSISIPHCIFQNQ-PGPEGSVPY 680

  Fly   964 V 964
            |
Mouse   681 V 681

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8414	NP_611084.2	HC2	41..>163	CDD:284736
		RNA_pol_3_Rpc31	<255..333	CDD:288542
		P-loop_NTPase	639..824	CDD:304359	54/210 (26%)
Nol9	NP_001365785.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	80..133
		Grc3	317..663	CDD:224260	83/358 (23%)
		CLP1_P	323..>455	CDD:406878	45/136 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167849767
Domainoid	1	1.000	75	1.000	Domainoid score	I9075
eggNOG	1	0.900	-	-		E1_COG1341
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005089
OrthoInspector	1	1.000	-	-		oto93344
orthoMCL	1	0.900	-	-		OOG6_103124
Panther	1	1.100	-	-	LDO	PTHR12755
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R523
SonicParanoid	1	1.000	-	-		X3611
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.730