Protein Alignment CG8388 and LOC1274221

DIOPT Version :10

• Sequence 1: NP_611075.1
• Gene: CG8388 / 36763
• FlyBaseID: FBgn0034062
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: XP_562406.5
• Gene: LOC1274221 / 1274221
• VectorBaseID: AGAMI1_012130
• Length: 768
• Species: Anopheles gambiae
• Alignment Length: 767
• Identity: 161/767 - (20%)
• Similarity: 269/767 - (35%)
• Gaps: 267/767 - (34%)

  Fly     3 CFLCTQTVDDAAGNIEFASEEADSLGLRCIIEKHFWLQIPDSKRAGYVCGPCWEQLLLFHNFYLN 67
            |.||..|  :....::..:||.....:..:|.||.|::   ..:..|||..||:.|..||.||..
Mosquito     7 CVLCLTT--EPQSFLKVYNEEKQDTDIASVITKHLWVK---PAKDSYVCDECWKCLNDFHEFYTK 66

  Fly    68 VEQAH------------KALEQTVLKETSPPEVV-------------------ASALEEHIVKSE 101
            :|..|            |.:.| .|.|..|.|.|                   ..|..|..:::|
Mosquito    67 LENIHYPPDPEDASCNAKDIRQ-YLFEFHPVEDVKIEELSQNAEDMEEIEYEYLEACNEETIENE 130

  Fly   102 HDDSVAAAVKRRRGRPRKVAQQDAREELKSV-----LEQINLNEIKIEFPEADLTIADV---LED 158
            :       .:|..|||::.:...|..::::.     .:.:..||.:.:..:.|...||.   .::
Mosquito   131 N-------AERSSGRPKRASAAQANYKIEAAESEWEKDYLATNEDEYDDDDDDDDEADADYNGDE 188

  Fly   159 QEEQDFLPDDCISKE--GAEDPEVLEKKPPTLKRKVS------GRSRGR-----RRVQLAERPNT 210
            :||.|:|.:|....|  ..:.|...:::|.|.|...|      .|.|||     ..:::...|.:
Mosquito   189 KEEVDYLEEDNDDSEVINYDSPSKAKQEPGTKKEPASEPTSPPKRGRGRPPKAKPEIEIKPEPKS 253

  Fly   211 SCLPKIQK------------SQEFNDYI-REHYKVQ----------------------------- 233
            ....:.:|            ..:|:|:| .|.:|..
Mosquito   254 KLRRRGRKRKVSVSSSDSELESDFDDFIDGEDWKKYRNTSKDKGRRSLGFRQLQEKIFSYVDEFI 318

  Fly   234 CHIC--NLPMEDFSEMLAHVRREHKQRGYAMC--CNRKFLKRGVLVDHLRRHQDPETFKCSICGR 294
            |:.|  .:..|.|.....|.::.|.:..:..|  |.:|....|..|.|:..|:|||..||.|||:
Mosquito   319 CYYCPEKIVFERFHHANLHYKKVHNEPAFLRCPKCGKKCFTPGGFVSHMETHEDPERNKCKICGK 383

  Fly   295 VMGHRRSLELHMRMHE-------------------------------------IKSRGR------ 316
            |.....:|:.|||.|:                                     .|.:||
Mosquito   384 VTDQEITLKKHMRAHQENLEKDFPYPCSLCNRRFEEEEKREKHERLHGRKVIIKKEKGRDLELLE 448

  Fly   317 ----------------------------------------------------------------- 316
                                                                             
Mosquito   449 FYKRIYCEVCEEKKPESTSFDNFWDLKVHMGNEHNKTPFLKCPICFKKNVCRQQLMVHVDVHNNP 513

  Fly   317 -LYRCEQCSKAFYSAVVYERHKL------THIPREQWKVPCTHCEKTYPSQYTMQQHVKLVH--- 371
             .||||.|.:...:   .|:|.:      |.:|.|: ...|.||.|.:..|..::.|:..||
Mosquito   514 ENYRCEVCKEIHQN---LEKHMIKAHTPETSLPDEK-NYSCEHCGKMFKYQTNLKSHIDRVHGVK 574

  Fly   372 ---------------LNLYAK--------ICDVCGKSIRGREALARHMEEHTGGPQAAIKCHLCD 413
                           |:.:.:        :|:.|.|..:.|..|..|..:|....:.:::|.:|.
Mosquito   575 DVSCDICHKYFNSKALSAHKRSAHTDEMFMCEHCPKMFKTRSGLESHKSDHDETLRKSVQCLICG 639

  Fly   414 SMLTTKYGLARHIKMMHTAENLQPMQCEFCLKICPSLQAHQHHIKYTHNT------ARSHQCPMC 472
            ..:.....:|:|:|.:|:.|:  |:.|:.|.|:   .:...|.:::..||      :|.::|.:|
Mosquito   640 KEMRRGASMAKHMKTIHSQED--PVSCDLCGKV---FRTTFHMMRHRANTCSATIDSRPYKCEVC 699

  Fly   473 EKAFKRPNELKEHMTTHTGEVLYTCPHCPQTFNSNANMHAHRKKVHRKEWEE 524
            .|.|.....:.|||||||...||.|..|.:||...:|::.||||.|..||:|
Mosquito   700 GKGFAMKLTMTEHMTTHTRTSLYQCAFCFKTFGYISNLYKHRKKAHPLEWQE 751

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8388	NP_611075.1	zf-AD	3..78	CDD:462262	23/86 (27%)
		C2H2 Zn finger	264..281	CDD:275368	5/16 (31%)
		C2H2 Zn finger	289..309	CDD:275368	9/19 (47%)
		C2H2 Zn finger	320..340	CDD:275368	5/25 (20%)
		C2H2 Zn finger	350..369	CDD:275368	6/18 (33%)
		C2H2 Zn finger	440..461	CDD:275368	4/20 (20%)
		C2H2 Zn finger	469..489	CDD:275368	8/19 (42%)
		C2H2 Zn finger	497..515	CDD:275368	6/17 (35%)
LOC1274221	XP_562406.5	None