DRSC/TRiP Functional Genomics Resources

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Protein Alignment Strn-Mlck and palld

DIOPT Version :10

Sequence 1:NP_001261019.1 Gene:Strn-Mlck / 36753 FlyBaseID:FBgn0265045 Length:8255 Species:Drosophila melanogaster
Sequence 2:XP_021324295.2 Gene:palld / 557660 ZFINID:ZDB-GENE-041014-252 Length:1401 Species:Danio rerio


Alignment Length:1445 Identity:296/1445 - (20%)
Similarity:477/1445 - (33%) Gaps:463/1445 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly  5575 DERVTKDARHKIYNINGAISLEIYDARVEDSGHYRCVVKNSRQTVESAGQLSVLDQSTGKLPESF 5639
            |..:...|.|.:...:|.:      |..:...::.|....|                    ||.|
Zfish   107 DHALPDSASHSVDATSGKV------ASSQSRQNHLCAASES--------------------PEKF 145

  Fly  5640 --SSGIIESYDDQRNEIVLSCQVIGRPSVSWMRDDHSICNNRYRTIEEPGGVRKLVIRNPISSDC 5702
              ...|...|...|..::.....:...:.|    ....|:.....|||...:.|...|.....| 
Zfish   146 VCQKSIAPVYKQDRPRLIHGGLELNERAAS----ATEFCSRAATFIEELSSIFKGSARVDPQGD- 205

  Fly  5703 GIFACYAEHEDRIDSTSITIKAADLKRLINVSQEEIPSIGDHESTPWSRSQSHLSSGSQVNGNGE 5767
                   |.....||..::.|:..|.    :.|.:.||.....|.|   .|..:..|....|:||
Zfish   206 -------EDSSSPDSGYLSPKSHRLA----MQQAQPPSSSSSSSEP---QQEGVLQGQADVGSGE 256

  Fly  5768 LHRAGDRVLRNVGKGKPLFHTLLHDRTVSEGANLRLVCSVSGDENTHIEWLKNHKPLPRSDNRYQ 5832
            |...|  |..:.....|.|...|..:.|:||:.:||.|.|:|:....:.|....:.|....:  .
Zfish   257 LQGGG--VSLDGPVAPPRFTQKLKSQEVAEGSPIRLECRVTGNPLPLVRWFCEGRELHHCPD--I 317

  Fly  5833 TVYLNGEA-SLEIFAAVADDSGNYTCCATNDFGESLTHAQ------------------------- 5871
            .:..:|:. :|.|..|..||:|.|||.|:|..|...|.|:                         
Zfish   318 QICRDGDLHTLVITEAFEDDTGRYTCVASNALGADNTSAEVYIEGASSSDSEGEGSVSKSRSGAM 382

  Fly  5872 -----------LRVYKNFKEAP-----------------------------------LPSTFTQP 5890
                       |.::.:..::|                                   .|.:||:.
Zfish   383 PQAQKKTSSVSLTIHTSSPKSPEAQPHRSTLVQPISTTPQRVQSPVSSLYAGDALAKAPPSFTKV 447

  Fly  5891 IRDTYSLNENELVLDCRVRGQPRPEIQWIKGTEPIEASEKF-----KPSDQA--DGYAKLVIVNP 5948
            ::|........:||:|||||.....:||.:..:.|:.|..|     ||...|  :....|||...
Zfish   448 LQDAQPSEGQVVVLECRVRGSLPLRVQWFREGQEIQDSPDFRILQKKPRSAAEPEEICTLVIAEA 512

  Fly  5949 TEKDSGIYWCVARNE-GAENKISHQVDFKGRQHYSLEKTHGFFHRDPNKPHFLLPLGNQTVCNGG 6012
            ..:|.|::.|.|.|| |:.|..:...                          :.|:..:...|| 
Zfish   513 FPEDGGLFCCTATNEYGSVNSTAQLT--------------------------VTPVAEEMPTNG- 550

  Fly  6013 TVAISAE---FMETST-------------PIEVKWLRDRRVVDGPNVKALADRGVYTLTIMNAGP 6061
               :|.:   |.:..:             |||:..|.     ..|.....|:  .:.:..::..|
Zfish   551 ---VSGDESVFEDNQSFPPPPPPLPPPPPPIEISLLE-----VPPKTPPSAE--AFQINELDIWP 605

  Fly  6062 EVEGTYTCRASNAFGRIESNVNVDVAVGAEK---DERP-----------PL--FLSRPDTEMKIA 6110
            .|..                  :.|.|..:|   :.||           ||  .||.|.:..:.|
Zfish   606 SVTA------------------LPVQVSTDKKPEESRPNKPLQNGQFTKPLDESLSSPSSVKETA 652

  Fly  6111 VGDPFSLSFR---IAGDPKPKLTFMKGTKDITQSDRVSKEVSDDYTRFSVQQAQISD-------- 6164
            ...|...:.|   :...|||||:       ..|:|.||.|      |.:||..|:.|        
Zfish   653 APPPSPSAVRAPPLPTKPKPKLS-------NEQADDVSNE------RNAVQLKQLQDQILLEQQQ 704

  Fly  6165 -----------------------SGTYFVVARNNFGTDRIFVT----------VTVNPRARSATP 6196
                                   ..:....:..|:...:.|:.          :..:.::.|::|
Zfish   705 LPAPQEVSPPSPPLPPPPSFQELESSTMQTSTFNYARPKQFIAAQSPTTSGAPIGYSSQSSSSSP 769

  Fly  6197 TQP--------RWGLP-------------LDSYSDTSYFRDPPGCISTEPLVVDSGPTHISLSWG 6240
            ..|        |..||             ::|.|..|:...||..:|:..|   |.|..:...:.
Zfish   770 LSPTTSHKPFSRVSLPPFHQQPLLSKSSSVESPSSPSFPPPPPPFLSSSNL---SSPAGLPQEFP 831

  Fly  6241 KPVSANSAPVMAYKVEAWVVGHEGGAYWRELGLTPINSFDAFNLKPNVEYHFRVTPKNRYGW--- 6302
            .|......||.:                     :|..|        :....|..||.:..|:   
Zfish   832 LPPPPPPPPVTS---------------------SPTRS--------DTSSPFTSTPHSPAGFLAS 867

  Fly  6303 -GPTVQTSSPLQV------GGVECLPEFVKILPGQAKALLGSSF---------TLQCNMRGAPRP 6351
             .||.....|:..      .|...||.  |..|...:.:..|..         .|:..:|     
Zfish   868 VLPTTPPPPPMNALGLPKGNGTVALPR--KTTPRTPRIISDSDIQGSKDAVIQDLERKLR----- 925

  Fly  6352 QVTWFKD-----GIQLSSSSERVKIRQIGSTCALTIATVSELDSGRYTCEATNSKG--------- 6402
                ||:     |.|..:..|::..|.:|:..|.|:....:::.     ||...:|         
Zfish   926 ----FKEERLSNGQQRLTYEEKMARRLLGADNAATVFNTQQVEE-----EANTQEGSADSESVPQ 981

  Fly  6403 ---RVSTFARLQVVSD-------SRIYEADSRLKEIAHGRNVADVGDSLPIFTMRLRDRRVQVTY 6457
               :||:|.: :::|:       |.:.|:|.   ::.|..:..  |:..|.|..:|:..:|....
Zfish   982 KEYKVSSFEQ-RLISEIEFRLERSPVEESDD---DVQHDEDAP--GEVAPSFDQKLKHYKVFEGM 1040

  Fly  6458 PVRLTCQIVGYPVPEILWYKDDELIHTDRKHL-ISAEGQ-FFTLEIAATTLDDSGTYTCLARNEL 6520
            ||..:|:::|.|.|::.|:||.:.|....:|. ||.:.. ..:|...|.:|||.|.||.:|.|..
Zfish  1041 PVTFSCKVMGDPKPKVYWFKDGKQISKRSEHYRISRDPDGTCSLHTTAASLDDDGNYTIMAGNPA 1105

  Fly  6521 GSVSCHCTLVV-------------------------DKG------IRAYISPDF-YVPLDPFYIF 6553
            |.|||...::|                         |.|      ...:..|.| ..|.|  .|.
Zfish  1106 GRVSCTGRMMVQAVNQRGRSQRSTPGHIRRPRSRSRDSGDENENIQERHFRPHFLQAPGD--LIV 1168

  Fly  6554 REGSEIRLSTKVEAYPSVGVTWHRNGMRLRPSRRLTATLDSNGYVELIIAEATVRDAGIYVCVAS 6618
            :||...|:..||...|:..:.|..||..:||.......:..||...|:|...|.||||:|.|:||
Zfish  1169 QEGKLCRMDCKVSGLPTPDLIWQLNGQTIRPDSFHKMLVRENGVHSLVIEPVTSRDAGVYTCIAS 1233

  Fly  6619 NVVGK----VETICRVAVEEAENKAVAPQRSLEIPSIKTDDLPYSKEPLFVVKPRSSEAYEGDNV 6679
            |..|:    :|.|  ||.:|..                       |.|.|:.|.:::...||..|
Zfish  1234 NRAGQNSFNLELI--VAAKEMH-----------------------KAPSFIEKLQNTSVAEGHPV 1273

  Fly  6680 IIFCEVVGDPKPEVVWLRDFLNPEYYKDAPHFRRIGDGPEYRLEI--PSAKLDFTGTYSVIASNC 6742
            .:.|.|.|.|.|::.|.::  |..:..:........|...|...|  |:.|.| .|.|:|.|.|.
Zfish  1274 RLECRVSGVPFPQIFWKKE--NESFTHNTDRISMHQDNFGYLCMIIQPALKED-AGWYTVSAKNE 1335

  Fly  6743 HGEAKAVISLQIFAK 6757
            .|...:...|.:.|:
Zfish  1336 AGIISSTARLDVHAQ 1350

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Strn-MlckNP_001261019.1 Ig_3 26..112 CDD:464046
Ig <70..112 CDD:472250
Ig strand E 92..96 CDD:409353
Ig strand F 106..111 CDD:409353
Ig 137..226 CDD:472250
Ig strand B 154..158 CDD:409353
Ig strand C 167..171 CDD:409353
Ig strand E 192..196 CDD:409353
Ig strand F 206..211 CDD:409353
Ig strand G 219..222 CDD:409353
Ig 235..314 CDD:472250
Ig strand B 251..255 CDD:409564
Ig strand C 264..268 CDD:409564
Ig strand E 280..284 CDD:409564
Ig strand F 294..299 CDD:409564
Ig strand G 307..310 CDD:409564
Ig_3 336..414 CDD:464046
Ig 438..513 CDD:472250
Ig strand B 454..458 CDD:409564
Ig strand C 467..471 CDD:409564
Ig strand E 483..487 CDD:409564
Ig strand F 493..498 CDD:409564
Ig strand G 506..509 CDD:409564
Ig 537..628 CDD:472250
Ig strand B 554..558 CDD:409353
Ig strand C 567..571 CDD:409353
Ig strand F 607..612 CDD:409353
Ig strand G 620..623 CDD:409353
Ig 636..713 CDD:472250
Ig strand B 652..656 CDD:409564
Ig strand C 665..669 CDD:409564
Ig strand E 681..685 CDD:409564
Ig strand F 695..700 CDD:409564
Ig strand G 708..711 CDD:409564
SMC_N <2131..2664 CDD:481474
PTZ00121 <2600..3256 CDD:173412
PTZ00121 <3635..4609 CDD:173412
PTZ00121 <4215..5072 CDD:173412
I-set 5300..5388 CDD:400151
Ig strand B 5317..5321 CDD:409353
Ig strand C 5329..5333 CDD:409353
Ig strand E 5354..5358 CDD:409353
Ig strand F 5368..5373 CDD:409353
Ig_3 5399..5477 CDD:464046
Ig 5542..5627 CDD:472250 7/51 (14%)
Ig strand B 5556..5560 CDD:409353
Ig strand C 5568..5572 CDD:409353
Ig strand E 5593..5597 CDD:409353 0/3 (0%)
Ig strand F 5607..5612 CDD:409353 1/4 (25%)
Ig 5654..5721 CDD:409353 11/66 (17%)
Ig strand B 5654..5658 CDD:409353 0/3 (0%)
Ig strand C 5665..5669 CDD:409353 1/3 (33%)
Ig strand E 5690..5694 CDD:409353 1/3 (33%)
Ig strand F 5704..5709 CDD:409353 0/4 (0%)
Ig strand G 5718..5721 CDD:409353 0/2 (0%)
I-set 5784..5874 CDD:400151 29/126 (23%)
Ig strand B 5801..5805 CDD:409353 2/3 (67%)
Ig strand C 5814..5818 CDD:409353 0/3 (0%)
Ig strand E 5840..5844 CDD:409353 1/4 (25%)
Ig strand F 5854..5859 CDD:409353 3/4 (75%)
Ig 5902..5963 CDD:409353 22/67 (33%)
Ig strand B 5902..5906 CDD:409353 2/3 (67%)
Ig strand C 5915..5919 CDD:409353 1/3 (33%)
Ig strand E 5941..5945 CDD:409353 1/3 (33%)
Ig strand F 5955..5960 CDD:409353 1/4 (25%)
Ig 5997..6086 CDD:472250 13/104 (13%)
Ig strand B 6014..6018 CDD:409353 0/3 (0%)
Ig strand C 6028..6032 CDD:409353 1/3 (33%)
Ig strand E 6050..6056 CDD:409353 0/5 (0%)
Ig strand F 6066..6071 CDD:409353 0/4 (0%)
Ig strand G 6079..6082 CDD:409353 0/2 (0%)
Ig 6107..6187 CDD:472250 20/123 (16%)
Ig strand B 6115..6119 CDD:409353 0/3 (0%)
Ig strand C 6128..6132 CDD:409353 2/3 (67%)
Ig strand E 6153..6157 CDD:409353 1/3 (33%)
Ig strand F 6167..6172 CDD:409353 0/4 (0%)
Ig strand G 6180..6183 CDD:409353 0/2 (0%)
FN3 6216..6310 CDD:238020 17/97 (18%)
I-set 6321..6412 CDD:400151 21/116 (18%)
Ig strand B 6339..6343 CDD:409353 1/12 (8%)
Ig strand C 6352..6356 CDD:409353 0/3 (0%)
Ig strand E 6375..6382 CDD:409353 2/6 (33%)
Ig strand F 6392..6397 CDD:409353 0/4 (0%)
Ig strand G 6405..6408 CDD:409353 1/2 (50%)
I-set 6442..6531 CDD:400151 31/90 (34%)
Ig strand B 6459..6463 CDD:409353 1/3 (33%)
Ig strand C 6472..6476 CDD:409353 0/3 (0%)
Ig strand E 6497..6501 CDD:409353 1/3 (33%)
Ig strand F 6511..6516 CDD:409353 2/4 (50%)
Ig strand G 6524..6527 CDD:409353 2/2 (100%)
Ig 6541..6632 CDD:472250 34/95 (36%)
Ig strand B 6559..6563 CDD:409353 1/3 (33%)
Ig strand C 6572..6576 CDD:409353 0/3 (0%)
Ig strand E 6598..6602 CDD:409353 1/3 (33%)
Ig strand F 6612..6617 CDD:409353 2/4 (50%)
Ig strand G 6625..6628 CDD:409353 1/2 (50%)
Ig 6662..6754 CDD:472250 26/93 (28%)
Ig strand B 6679..6683 CDD:409353 1/3 (33%)
Ig strand C 6692..6696 CDD:409353 0/3 (0%)
Ig strand E 6720..6724 CDD:409353 1/3 (33%)
Ig strand F 6734..6739 CDD:409353 2/4 (50%)
I-set 6779..6868 CDD:400151
Ig strand B 6796..6800 CDD:409353
Ig strand C 6809..6813 CDD:409353
Ig strand E 6834..6838 CDD:409353
Ig strand F 6848..6853 CDD:409353
I-set 6939..7028 CDD:400151
Ig strand B 6956..6960 CDD:409353
Ig strand C 6969..6973 CDD:409353
Ig strand E 6993..6998 CDD:409353
Ig strand F 7008..7013 CDD:409353
Ig strand G 7021..7024 CDD:409353
IG_like 7075..7140 CDD:214653
Ig strand C 7082..7086 CDD:409353
Ig strand E 7107..7111 CDD:409353
Ig strand F 7121..7126 CDD:409353
Ig strand G 7135..7138 CDD:409353
Ig 7173..7232 CDD:409353
Ig strand C 7184..7188 CDD:409353
Ig strand E 7210..7214 CDD:409353
Ig strand F 7224..7229 CDD:409353
IG_like 7406..7475 CDD:214653
Ig strand B 7413..7417 CDD:409353
Ig strand C 7426..7430 CDD:409353
Ig strand E 7451..7455 CDD:409353
Ig strand F 7465..7470 CDD:409353
FN3 7489..7588 CDD:238020
STKc_MLCK 7626..7876 CDD:271005
palldXP_021324295.2 None
Blue background indicates that the domain is not in the aligned region.

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