Protein Alignment CG8299 and KLK4

DIOPT Version :10

• Sequence 1: NP_611066.1
• Gene: CG8299 / 36751
• FlyBaseID: FBgn0034052
• Length: 260
• Species: Drosophila melanogaster
• Sequence 2: NP_004908.4
• Gene: KLK4 / 9622
• HGNCID: 6365
• Length: 254
• Species: Homo sapiens
• Alignment Length: 258
• Identity: 88/258 - (34%)
• Similarity: 136/258 - (52%)
• Gaps: 20/258 - (7%)

  Fly     5 LGLFLLAALGVVILTDSASISTHIVGGDQADIADFPYQVSVRLETYMLLHICGGSIYAPRVVITA 69
            ||..:|...|.::   |.|.| .|:.|:.......|:|.::.:|..:   .|.|.:..|:.|::|
Human    12 LGYLILGVAGSLV---SGSCS-QIINGEDCSPHSQPWQAALVMENEL---FCSGVLVHPQWVLSA 69

  Fly    70 AHCIKGRYASYIRIVAGQNSI-ADLE--EQGVKVSKLIPHAGYNKKTYVNDIGLIITREPLEYSA 131
            |||.:..|.    |..|.:|: ||.|  .|.|:.|..:.|..||:....||:.||...|.:..|.
Human    70 AHCFQNSYT----IGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESD 130

  Fly   132 LVQPIAVALEAPPSGAQAVVSGWGKRAEDDEALPAMLRAVELQIIEKSTCGAQYLTKDYTVTDEM 196
            .::.|::|.:.|.:|...:|||||..|  :..:|.:|:.|.:.::.:..|...|   |......|
Human   131 TIRSISIASQCPTAGNSCLVSGWGLLA--NGRMPTVLQCVNVSVVSEEVCSKLY---DPLYHPSM 190

  Fly   197 LCAGYLEGGKDTCNGDSGGPLAVDGVLVGVVSWG-VGCGREGFPGVYTSVNSHIDWIEEQAEA 258
            .|||..:..||:|||||||||..:|.|.|:||:| ..||:.|.|||||::....:|||:..:|
Human   191 FCAGGGQDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQA 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8299	NP_611066.1	Tryp_SPc	27..252	CDD:214473	77/228 (34%)
KLK4	NP_004908.4	Tryp_SPc	31..250	CDD:238113	80/230 (35%)