DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8299 and CG18754

DIOPT Version :9

Sequence 1:	NP_611066.1	Gene:	CG8299 / 36751	FlyBaseID:	FBgn0034052	Length:	260	Species:	Drosophila melanogaster
Sequence 2:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster

Alignment Length:	247	Identity:	62/247 - (25%)
Similarity:	105/247 - (42%)	Gaps:	41/247 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 GGDQADIADFPYQVSVRLETYMLLHICGGSIYAPRVVITAAHCIKGRYASYIRIV-----AGQNS 89
            |.:.|::.::|:.|.:..|..:.|         .|.|:|||||:.|.|.:...:|     .|:::
  Fly   108 GAENAELNEYPWMVLLLYENRLSL---------IRYVLTAAHCVIGGYLTQNDLVLKSVRLGEST 163

  Fly    90 IADLEEQG------VKVSKLIPHAGYNKK--TYVNDIGLIITREPLEYSALVQPIAVA-LEAPPS 145
            ...:..:.      |:|.:...|.|:...  ||.|||.|:..:.|:.|:..:|||.:. .|.|..
  Fly   164 TDCITSESRCPHLDVEVGQTTVHQGFTSSGGTYRNDIALLRLQFPVRYTKKIQPICLLDAEFPLQ 228

  Fly   146 GAQAVVSGWGKRAEDDEALPAMLRAVELQIIEKSTCGAQYLTKDYTVTDEMLCAGYLEGGKDTCN 210
            .....:|||.........:.:.::       |::..........:....::...|..:|  |||.
  Fly   229 DLNLQISGWDPTKSSQTLITSTVK-------ERNPADCLNRYPSFRSASQVCAGGQRKG--DTCA 284

  Fly   211 GDSGGPL------AVDG--VLVGVVSWGVG-CGREGFPGVYTSVNSHIDWIE 253
            |.||.|:      .||.  .|.|:.|:|.. |...|.|||||.:....:||:
  Fly   285 GISGSPVMGIMGSGVDEFVFLAGIASYGQQYCYSAGIPGVYTKIGHFSEWIK 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8299	NP_611066.1	Tryp_SPc	27..252	CDD:214473	60/244 (25%)
CG8299	NP_611066.1	Tryp_SPc	28..255	CDD:238113	62/247 (25%)
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	62/247 (25%)
		Tryp_SPc	108..335	CDD:214473	60/244 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910