DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8299 and F9

DIOPT Version :9

Sequence 1:	NP_611066.1	Gene:	CG8299 / 36751	FlyBaseID:	FBgn0034052	Length:	260	Species:	Drosophila melanogaster
Sequence 2:	NP_032005.1	Gene:	F9 / 14071	MGIID:	88384	Length:	471	Species:	Mus musculus

Alignment Length:	266	Identity:	90/266 - (33%)
Similarity:	142/266 - (53%)	Gaps:	37/266 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 LTDSASIS------------THIVGGDQADIADFPYQVSV--RLETYMLLHICGGSIYAPRVVIT 68
            :||.|.::            |.:|||:.|.....|:||.:  .:|.:     |||:|...:.::|
Mouse   215 ITDGAILNNVTESSESLNDFTRVVGGENAKPGQIPWQVILNGEIEAF-----CGGAIINEKWIVT 274

  Fly    69 AAHCIKGRYASYIRIVAGQNSIADLE--EQGVKVSKLIPHAGYNK--KTYVNDIGLIITREPLEY 129
            ||||:|.  ...|.:|||:.:|...|  ||...|.:.|||..||.  ..|.:||.|:...:||..
Mouse   275 AAHCLKP--GDKIEVVAGEYNIDKKEDTEQRRNVIRTIPHHQYNATINKYSHDIALLELDKPLIL 337

  Fly   130 SALVQPIAVALEAPPS----GAQAVVSGWGKRAEDDEALPAMLRAVELQIIEKSTCGAQYLTKDY 190
            ::.|.||.||.....:    .....|||||| ..:.....::|:.:.:.:::::||   ..:..:
Mouse   338 NSYVTPICVANREYTNIFLKFGSGYVSGWGK-VFNKGRQASILQYLRVPLVDRATC---LRSTTF 398

  Fly   191 TVTDEMLCAGYLEGGKDTCNGDSGGP--LAVDGV--LVGVVSWGVGCGREGFPGVYTSVNSHIDW 251
            |:.:.|.||||.|||||:|.||||||  ..|:|.  |.|::|||..|..:|..|:||.|:.:::|
Mouse   399 TIYNNMFCAGYREGGKDSCEGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNW 463

  Fly   252 IEEQAE 257
            |:|:.:
Mouse   464 IKEKTK 469

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8299	NP_611066.1	Tryp_SPc	27..252	CDD:214473	83/238 (35%)
CG8299	NP_611066.1	Tryp_SPc	28..255	CDD:238113	85/240 (35%)
F9	NP_032005.1	GLA	28..92	CDD:214503
		EGF_CA	93..129	CDD:238011
		FXa_inhibition	134..170	CDD:291342
		Tryp_SPc	236..464	CDD:214473	83/238 (35%)
		Tryp_SPc	237..467	CDD:238113	85/240 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910