DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8299 and hgf

DIOPT Version :9

Sequence 1:	NP_611066.1	Gene:	CG8299 / 36751	FlyBaseID:	FBgn0034052	Length:	260	Species:	Drosophila melanogaster
Sequence 2:	XP_002933142.2	Gene:	hgf / 100495840	XenbaseID:	XB-GENE-999992	Length:	710	Species:	Xenopus tropicalis

Alignment Length:	270	Identity:	66/270 - (24%)
Similarity:	99/270 - (36%)	Gaps:	68/270 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 LTDSASISTHIVGGDQADIADFPYQ------VSVRLETYMLLHICGGSIYAPRVVITAAHCIKGR 76
            :|.|:|....:|.|       .|.|      ||||   |...|.|||::.....|:||..|
Frog   468 ITCSSSKQLRVVNG-------IPTQTRKVWMVSVR---YRNSHKCGGTLIKENWVLTARQC---- 518

  Fly    77 YASYIRIVAGQNSIADLE---------------EQGVKVSKLIPHA--GYNKKTYVNDIGLIITR 124
                  .::|.|.:.|.|               :|.:.:|:|: |.  |.|       :.|:...
Frog   519 ------FLSGDNDLKDYEAWLGVHNIYSTTEKHKQVLNISQLV-HGPKGSN-------LVLLKLS 569

  Fly   125 EPLEYSALVQPIAVALEAP------PSGAQAVVSGWGKRAEDDEALPAMLRAVELQIIEKSTCGA 183
            .|...:|.|..|    :.|      |......|.|||....:|  ....|:...|.|:....|..
Frog   570 RPATLNAYVDRI----KLPNYGCTIPENTMCSVYGWGHTGTND--YDGQLQEGTLHIVGNEKCNE 628

  Fly   184 QYLTKDYTVTDEMLCAGYLEGGKDTCNGDSGGPLAVD----GVLVGVVSWGVGCGREGFPGVYTS 244
            .:..| .||.:..:||.........|..|.||||..:    .::.||:..|.||..:..|.::..
Frog   629 HHKGK-ITVNESEICAMSETANIGPCERDYGGPLICEENRTHLVQGVIIPGRGCAIQKRPVIFVR 692

  Fly   245 VNSHIDWIEE 254
            |..:..||.:
Frog   693 VAYYAKWIHK 702

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8299	NP_611066.1	Tryp_SPc	27..252	CDD:214473	61/257 (24%)
CG8299	NP_611066.1	Tryp_SPc	28..255	CDD:238113	63/260 (24%)
hgf	XP_002933142.2	PAN_AP_HGF	26..109	CDD:238532
		KR	113..195	CDD:214527
		KR	197..275	CDD:214527
		Kringle	289..367	CDD:333799
		KR	373..454	CDD:238056
		Tryp_SPc	478..703	CDD:238113	63/260 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910