Protein Alignment Cdk5 and KDX1

DIOPT Version :10

• Sequence 1: NP_477080.1
• Gene: Cdk5 / 36727
• FlyBaseID: FBgn0013762
• Length: 294
• Species: Drosophila melanogaster
• Sequence 2: NP_012761.1
• Gene: KDX1 / 853696
• SGDID: S000001644
• Length: 433
• Species: Saccharomyces cerevisiae
• Alignment Length: 301
• Identity: 102/301 - (33%)
• Similarity: 168/301 - (55%)
• Gaps: 31/301 - (10%)

  Fly     9 KIGEGTYGTV----FKGRNRDTMEIVALKRVRLDEDDEGVPSSALREICLLKELK-HKNIVRLID 68
            |||.|::..:    :...|.:|.  ||::::.....::......|||:.||:.|: |.|||.|.|
Yeast    28 KIGRGSHSLICSSTYTESNEETH--VAIRKIPNAFGNKLSCKRTLRELKLLRHLRGHPNIVWLFD 90

  Fly    69 ---VLHSDKKLTLVF---EHCDQDLKKYFDSLNGEIDMAVCRSFMLQLLRGLAFCHSHNVLHRDL 127
               |.:.:..|..|:   |..:.||.:...| ...::.|..:||:.|:|..|.:.||.||||.||
Yeast    91 TDIVFYPNGALNGVYLYEELMECDLSQIIRS-EQRLEDAHFQSFIYQILCALKYIHSANVLHCDL 154

  Fly   128 KPQNLLINKNGELKLADFGLARAF--------GIPVKCYSAEVVTLWYRPPDVLFGAKLYTTSID 184
            ||:|||:|.:.:||:.:|||:.::        |. :|.|   :.::||:.|::|...:..|.::|
Yeast   155 KPKNLLVNSDCQLKICNFGLSCSYSENHKVNDGF-IKGY---ITSIWYKAPEILLNYQECTKAVD 215

  Fly   185 MWSAGCILAELADAGR-PLFPGSDVLDQLMKIFRVLGTPNEDSWPGVSHLSDYVALPSFPAI--T 246
            :||.|||||||  .|| |:|.|.|.:|.|..|.::||||.|::...::....|..:..|..|  .
Yeast   216 IWSTGCILAEL--LGRKPMFEGKDYVDHLNHILQILGTPPEETLQEIASQKVYNYIFQFGNIPGR 278

  Fly   247 SWSQLVPRLNSKGRDLLQKLLICRPNQRISAEAAMQHPYFT 287
            |:..::|..|.:..:||:|:|...|.:||:.|.|::|||.:
Yeast   279 SFESILPGANPEALELLKKMLEFDPKKRITVEDALEHPYLS 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk5	NP_477080.1	STKc_CDK5	3..286	CDD:143344	101/298 (34%)
KDX1	NP_012761.1	STKc_MPK1	22..355	CDD:173750	102/301 (34%)