Protein Alignment Cdk5 and HOG1

DIOPT Version :10

• Sequence 1: NP_477080.1
• Gene: Cdk5 / 36727
• FlyBaseID: FBgn0013762
• Length: 294
• Species: Drosophila melanogaster
• Sequence 2: NP_013214.1
• Gene: HOG1 / 850803
• SGDID: S000004103
• Length: 435
• Species: Saccharomyces cerevisiae
• Alignment Length: 287
• Identity: 99/287 - (34%)
• Similarity: 158/287 - (55%)
• Gaps: 11/287 - (3%)

  Fly     3 KYDKMEKIGEGTYGTVFKGRNRDTMEIVALKRVRLDEDDEGVPSSALREICLLKELKHKNIVRLI 67
            :|:.:..:|.|.:|.|....:..|.:.||:|::........:.....||:.|||.|:|:|::.|.
Yeast    22 RYNDLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTAVLAKRTYRELKLLKHLRHENLICLQ 86

  Fly    68 DVLHSD-KKLTLVFEHCDQDLKKYFDSLNGEIDMAVCRSFMLQLLRGLAFCHSHNVLHRDLKPQN 131
            |:..|. :.:..|.|....||.:...:  ..::....:.|:.|:||||.:.||..|:||||||.|
Yeast    87 DIFLSPLEDIYFVTELQGTDLHRLLQT--RPLEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSN 149

  Fly   132 LLINKNGELKLADFGLARAFGIPVKCYSAEVVTLWYRPPDVLFGAKLYTTSIDMWSAGCILAELA 196
            :|||:|.:||:.||||||.....:..|   |.|.:||.|:::...:.|...:|:||||||.||:.
Yeast   150 ILINENCDLKICDFGLARIQDPQMTGY---VSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMI 211

  Fly   197 DAGRPLFPGSDVLDQLMKIFRVLGTPNEDSWPGV---SHLSDYVALPSFPAITSWSQLVPRLNSK 258
            : |:|||||.|.:.|...|..:||:|.:|....:   :.|....:||....| .:|:....:...
Yeast   212 E-GKPLFPGKDHVHQFSIITDLLGSPPKDVINTICSENTLKFVTSLPHRDPI-PFSERFKTVEPD 274

  Fly   259 GRDLLQKLLICRPNQRISAEAAMQHPY 285
            ..|||:|:|:..|.:||:|..|:.|||
Yeast   275 AVDLLEKMLVFDPKKRITAADALAHPY 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk5	NP_477080.1	STKc_CDK5	3..286	CDD:143344	99/287 (34%)
HOG1	NP_013214.1	STKc_Sty1_Hog1	12..339	CDD:270843	99/287 (34%)