Protein Alignment Cdk5 and cdkl1

DIOPT Version :10

• Sequence 1: NP_477080.1
• Gene: Cdk5 / 36727
• FlyBaseID: FBgn0013762
• Length: 294
• Species: Drosophila melanogaster
• Sequence 2: NP_001003773.1
• Gene: cdkl1 / 445316
• ZFINID: ZDB-GENE-040808-34
• Length: 350
• Species: Danio rerio
• Alignment Length: 288
• Identity: 114/288 - (39%)
• Similarity: 165/288 - (57%)
• Gaps: 3/288 - (1%)

  Fly     1 MQKYDKMEKIGEGTYGTVFKGRNRDTMEIVALKRVRLDEDDEGVPSSALREICLLKELKHKNIVR 65
            |:||:|:.|||||:||.|||.||:||.:|||:|:....|||..:...|||||.:||:|||.|:|.
Zfish     1 MEKYEKISKIGEGSYGVVFKCRNKDTGQIVAIKKFVESEDDPIIKKIALREIRMLKQLKHPNLVN 65

  Fly    66 LIDVLHSDKKLTLVFEHCDQDLKKYFDSLNGEIDMAVCRSFMLQLLRGLAFCHSHNVLHRDLKPQ 130
            |::|....:||.||||:||..:....|.....:...:.:|.:.|.|:.:.|||..|.:|||:||:
Zfish    66 LMEVFRRKRKLHLVFEYCDHTVLNELDRYPRGVPEHMVKSIIWQTLQAVNFCHKQNCIHRDVKPE 130

  Fly   131 NLLINKNGELKLADFGLARAFGIPVKCYSAEVVTLWYRPPDVLFGAKLYTTSIDMWSAGCILAEL 195
            |:||.|:..:||.|||.||....|...|:..|.|.|||.|::|.|...|...:|:|:.||:.|||
Zfish   131 NILITKHQVIKLCDFGFARILTGPCDYYTDCVATRWYRAPELLVGDTQYGPPVDVWAVGCVFAEL 195

  Fly   196 ADAGRPLFPGSDVLDQLMKIFRVLG--TPNEDSWPGVSHLSDYVALPSFPAITSWSQLVPRLNSK 258
            . :|.||:||...:|||..|.:.||  .|........:.....|.:|....:.......|.|:.:
Zfish   196 L-SGAPLWPGKSDVDQLYLIRKTLGELIPRHQQVFSTNQFFSGVCVPEPQEMEPLELKYPNLSYQ 259

  Fly   259 GRDLLQKLLICRPNQRISAEAAMQHPYF 286
            ...|::..|...|.:|:|.|..::.|||
Zfish   260 ALSLMKGCLRMDPAERLSCEQLLEQPYF 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk5	NP_477080.1	STKc_CDK5	3..286	CDD:143344	111/284 (39%)
cdkl1	NP_001003773.1	STKc_CDKL1_4	2..287	CDD:270837	111/285 (39%)
		[NKR]KIAxRE	45..51		2/5 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	293..318